Application of intermediate biomarkers to studies of cancer prevention in the gastrointestinal tract: Introduction and perspective

American Journal of Clinical Nutrition

Volumn 54, Issue SUPPL. 1, 1991, Pages

  Lipkin, Martin ^a,b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b NONE   (United States)

Author keywords

Biomarkers; Cancer prevention; Cell proliferation

Indexed keywords

CALCIUM;

CARCINOGENESIS; CONFERENCE PAPER; DIGESTIVE SYSTEM CANCER; HUMAN; NONHUMAN; PRIORITY JOURNAL;

ANIMAL; BIOLOGICAL MARKERS; EPITHELIUM; ESOPHAGEAL DISEASES; GASTROINTESTINAL DISEASES; GASTROINTESTINAL NEOPLASMS; GASTROINTESTINAL SYSTEM; HUMAN; HYPERPLASIA; INTESTINAL DISEASES; STOMACH DISEASES; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

RODENTIA;

EID: 0025880752     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/54.1.188S     Document Type: Article

References (55)

1. Lipkin M. Biomarkers of increased susceptibility to gastrointestinal cancer: new application to studies of cancer prevention in human subjects. Perspectives in cancer research. Cancer Res 1988;48:235-45.
2. Naef AP, Savary M, Ozzello L. Columnar lined lower esophagus: an acquired lesion with malignant predisposition. Report on 140 cases of Barrett's esophagus with 12 adenocarcinoma. J Thorac Cardiovasc Surg 1975;70:826-35.
3. Herbst JJ, Berenson MM, McCloskey DW, Wiser WC. Cell proliferation in esophageal columnar epithelium (Barrett's esophagus). Gastroenterology 1978;75:683-7.
4. Li JY. Epidemiology of esophageal cancer in China. Natl Cancer Inst Monogr 1981;62:113-20.
5. Yang GC, Lipkin M, Yang K et al. Proliferation of esophageal epithelial cells in individuals in Linxian, China. J Natl Cancer Inst 1987;79:1241-6.
6. Doran TI, Vidrich A, Sun T-T. Intrinsic and extrinsic regulation of the differentiation of skin, corneal and esophageal epithelial cells. Cell 1980;22:17-25.
7. Burg-Kurland CL, Purnell DM, Combs JW, Hillman EA, Harris CC, Trump BF. Immunocytochemical evaluation of human esophageal neoplasms and preneoplastic lesions for beta-chorionic gonadotropin, placental lactogen, alphafetoprotein, carcinoembryonic antigen, and nonspecific cross-reacting antigen. Cancer Res 1986;46: 2936-43.
8. Deschner E, Winawer SJ, Lipkin M. Patterns of nucleic acid and protein synthesis in normal human gastric mucosa and atrophic gastritis. J Natl Cancer Inst 1972;48:1567-74.
9. Sizikov AI, Azykbekov R. Histoautoradiographic study of gastric epithelial DNA synthesis in precancerous lesions of the stomach. Vopr Onkol 1981;27:19-22.
10. Lipkin M, Correa P, Mikol YB, et al. Proliferative and antigenic modifications in epithelial cells in chronic atrophic gastritis. J Natl Cancer Inst 1985;75:613-9.
11. Offerhaus GJA, van de Stadt J, Samson G, Tytgat GNJ. Cell proliferation kinetics in the gastric remnant. Eur J Cancer Clin Oncol 1985;21:73-9.
12. Correa P. Chronic gastritis as a cancer precursor. Scand J Gastroenterol 1984;19:131-6.
13. Lightdale C, Lipkin M, Deschner E. In vivo measurements in familial polyposis: kinetics and location of proliferating cells in colonic adenomas. Cancer Res 1982;42:4280-3.
14. Biasco G, Lipkin M, Minarini A, Higgins P, Miglioli M. Proliferative and antigenic properties of the rectal cells in patients with chronic ulcerative colitis. Cancer Res 1984;44:5450-4.
15. Friedman E, Gillin S, Lipkin M. 12-O-tetradecanoylphorbol-13-acetate stimulation of DNA synthesis in cultured preneoplastic familial polyposis colonic epithelial cells but not in normal colonic epithelial cells. Cancer Res 1984;44:4078-86.
16. Sakamoto J, Furukawa K, Cordon-Cardo C, et al. Expression of Lewisa, Lewisb, X, and Y blood group antigens in human colonic tumors and normal tissue and in human tumor-derived cell lines. Cancer Res 1986;46:1553-61.
17. Kim YS, Yuan M, Itzkowitz SH, et al. Expression of LeY and extended LeY blood group-related antigens in human malignant, premalignant, and nonmalignant colonic tissues. Cancer Res 1986;46: 5985-92.
18. Bodmer WF, Bailey CJ, Bodmer J, et al. Localization of the gene for familial adenomatous polyposis on chromosome 5. Nature 1987;328:614-6.
19. Augenlicht LH, Wahrman MZ, Halsey H, Anderson L, Taylor J, Lipkin M. Expression of cloned sequences in biopsies of human colonic tissue and in colonic carcinoma cells induced to differentiate in vitro. Cancer Res 1987;47:6017-21.
20. Chesa PG, Rettig WJ, Melamed MR, Old LJ, Niman HL. Expression of p21 rats in normal and malignant tissues, lack of association with proliferation and malignancy. Proc Natl Acad Sci USA 1987;84: 3234-8.
21. Augenlicht LH, Augeron C, Yander G, Laboisse C. Overexpression of ras in mucus-secreting colon carcinoma cells of low tumorigenicity. Cancer Res 1987;47:3763-5.
22. Vogelstein B, Fearon ER, Hamilton SR, et al. Genetic alterations during colorectal-tumor development. New Engl J Med 1988;319: 525-32.
23. Telang NT, Basu A, Kurihara H, Osborne MP, Modak MJ. Modulation in the expression of murine mammary tumor virus, ras protooncogene, and of alveolar hyperplasia by fatty acids in mouse mammary explant cultures. Anticancer Res 1988;8:971-6.
24. Wattenberg LW. Chemoprevention of cancer. Cancer Res 1985;45: 1-8.
25. Lipkin M, Newmark H. Effect of added dietary calcium on colonic epithelial cell proliferation in subjects at high-risk for familial colon cancer. N Engl J Med 1985;313:1381-4.
26. Lipkin M, Friedman E, Winawer SJ, Newmark HL. Colonic epithelial cell proliferation in responders and nonresponders to supplemental dietary calcium. Cancer Res 1989;49:248-54.
27. Rozen P, Fireman Z, Fine N, Wax Y, Ron E. Oral calcium suppresses increased rectal epithelial proliferation of persons at risk of colorectal cancer. Gut 1989;30:650-5.
28. Isbell G, Hu P-J, Lanza F, et al. Modulation by calcium of colonic mucosal proliferation in patients with sporadic colonic adenomas and carcinomas. Gastroenterology 1989;96:A228(abstr).
29. Gregoire RC, Stern HS, Yeung KS, et al. Effect of calcium supplementation on mucosal cell proliferation in high risk patients for colon cancer. Gut 1989;30:376-82.
30. Buset M, Lipkin M, Winawer S, Swaroop S, Friedman E. Inhibition of human colonic epithelial cell proliferation in vivo and in vitro by calcium. Cancer Res 1986;46:5426-30.
31. Appleton GVN, Wheeler EE, Owen RW, Challecombe DN. Intralumenal calcium and colonic cancer: possible mechanism of action. Gastroenterology 1988;94:A10(abstr).
32. Arlow FL, Walczak SM, Majumdar APN. The role of calcium in deoxycholic acid-induced hyperproliferation of colonic mucosal explants. Gastroenterology 1988;94:A12(abstr).
33. Buset M, Lipkin M, Winawer S, Friedman E. Direct and indirect protection of human colonic epithelial cells by calcium. Gastroenterology 1987;92:1334.
34. Friedman E, Lipkin M, Winawer S, Buset M, Newmark H. Heterogeneity in the response of familial polyposis cells and adenomas to increasing levels of calcium in vitro. Cancer 1989;63:2486-91.
35. Buset M, Galand P, Lipkin M, Winawer S, Friedman E. Protection of human colonic epithelial cells from toxicity of biliary and fatty acids by calcium. Gastroenterology 1989;96:A66(abstr).
36. Boffa LC, Mariani MR, Newmark H, Lipkin M. Calcium as modulator of nucleosomal histones acetylation in cultured cells. Proc Am Assoc Cancer Res 1989;30:8.
37. Wargovich MJ, Eng VWS, Newmark HL, Bruce WR. Calcium ameliorates the toxic effects of deoxycholic acid on colonic epithelium. Carcinogenesis 1983;4:1205-7.
38. Wargovich MJ, Eng VWS, Newmark HL, Bruce WR. Calcium inhibits the damaging and compensating proliferative effects of fatty acids on mouse colon epithelium. Cancer Lett 1984;23:253-8.
39. Bird RP, Schneider R, Stamp D, Bruce WR. Effect of dietary calcium and cholic acid on the proliferative indices of murine colonic epithelium. Carcinogenesis 1986;7:1657-61.
40. Appleton GVN, Bristol JB, Williamson RCN. Increased dietary calcium and small bowel resection have opposite effects on colonic cell turnover. Br J Surg 1986;73:1018-21.
41. Appleton GVN, Davies PW, Bristol JB, Williamson RCN. Inhibition of intestinal carcinogenesis by dietary supplementation with calcium. Br J Surg 1987;74:523-5.
42. Pence BC, Buddingh F. Inhibition of dietary fat promotion of colon carcinogenesis by supplemental calcium or vitamin D. Proc Am Assoc Cancer Res 1987;28:154.
43. Skrypec DJ, Bursey RG. Effect of dietary calcium on azoxymethane-induced intestinal carcinogenesis in male F344 rats fed high fat diets. FASEB J 1988;2:A857(abstr).
44. Newmark H, Lipkin M, Maheshwari N. Colonic hyperplasia and hyperproliferation induced by a nutritional stress diet with four components of western-style diet. J Natl Cancer Inst 1990;82:491-6.
45. Reshef R, Rozen P, Fireman Z, et al. Effect of calcium administration on colonic epithelial cell proliferation in rats during cancer induction by MNNG. Proc Am Assoc Cancer Res 1989;30:179.
46. Wargovich MJ, Allnutt D, Palmer C, Anaya P, Stephens LC. Inhibition of the promotional phase of azoxymethane-induced colon carcinogenesis in the F344 rat by calcium lactate: effect of simulating 2 human nutrient density levels. Cancer Lett (in press).
47. Hu PJ, Baer AR, Wargovich MJ. Calcium and phosphate: effect of two dietary confounders on colonic epithelial cellular proliferation. Nutr Res 1989;9:545-53.
48. Arlow FL, Walczak S, Majumdar APN. Attenuation of azoxymethane (AOM)-induced colonic mucosal ornithine decarboxylase (ODC) and tyrosine kinase (TYR-K) activity by calcium in rats. Gastroenterology 1989;96:A14(abstr).
49. 3 (Vit D) inhibit colonic ornithine decarboxylase (ODC) activity induced by bile acids. FASEB J 1989;3:A469(abstr).
50. Cohen BI, Mosbach EM, McSherry CK, Matoba N, Stenger RJ. Dietary calcium ameliorates cholic acid toxicity in a hamster model of cholelithiasis. Gastroenterology 1989;58:A586(abstr).
51. Karkare M, Patrick PC, Glauert HP. Effect of dietary calcium and vitamin D on colon tumors induced by 1,2-dimethylhydrazine in Fischer-344 rats. FASEB J 1989;3:A472(abstr).
52. Kaup SM, Behling AR, Choquette LL, Greger JL. Colon tumor development in DMH-initiated rats fed varying levels of calcium and butterfat. FASEB J 1989;3:A469(abstr).
53. Zhang L, Bruce WR, Bird RP. Proliferative activity of murine mammary epithelium as affected by dietary fat and calcium. Cancer Res 1987;47:4905-8.
54. Carroll KK, Jacobson EA, Eckel LA, Newmark HL. Calcium and carcinogenesis of the mammary gland. Am J Clin Nutr (in press).
55. Telang NT, Bradlow HL, Kurihara H, Osborne MP. In vitro biotransformation of estradiol by explant cultures of murine mammary tissues. Breast Cancer Res Treat 1989;13:173-81.