Neuropsychological Function in Schizophrenia: Selective Impairment in Memory and Learning

Archives of General Psychiatry

Volumn 48, Issue 7, 1991, Pages 618-624

  Saykin, Andrew J ^a   Gur, Ruben C ^a   Gur, Raquel E ^a   Mozley, P David ^a   Mozley, Lyn H ^a   Resnick, Susan M ^a   Kester, D Brian ^a   Stafiniak, Paul ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; CLINICAL ARTICLE; CONFERENCE PAPER; HIPPOCAMPUS; HUMAN; LEARNING; MEMORY; PRIORITY JOURNAL; SCHIZOPHRENIA; TEMPORAL LOBE;

ADULT; ATTENTION; BRAIN; FEMALE; HIPPOCAMPUS; HUMAN; LATERALITY; LEARNING; MALE; MEMORY; NEUROPSYCHOLOGICAL TESTS; PSYCHOMETRICS; PSYCHOMOTOR PERFORMANCE; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; SUPPORT, U.S. GOV'T, P.H.S.; TEMPORAL LOBE;

EID: 0025879236     PISSN: 0003990X     EISSN: 15383636     Source Type: Journal    
DOI: 10.1001/archpsyc.1991.01810310036007     Document Type: Article

References (84)

1. Malec J. Neuropsychological assessment of schizophrenia versus brain damage: a review. J Nerv Ment Dis. 1978; 166:507-516.
2. Heaton RK, Baade LE, Johnson KL. Neuropsychological test results associated with psychiatric disorders in adults. Psychol Bull. 1978;85:141-162.
3. Goldstein G. The neuropsychology of schizophrenia. In: Grant I, Adams KM, eds. Neuropsychological Assessment of Neuropsychiatric Disorders. New York, NY: Oxford University Press; 1986.
4. Flor-Henry P, Fromm-Auch D, Schopflocher D. Neuropsychological dimensions in psychopathology. In: Laterality and Psychopathology. Amsterdam, the Netherlands: Elsevier Bio-Medical Press; 1983.
5. Levin S, Yurgelun-Todd D, Craft S. Contributions of clinical neuropsychology to the study of schizophrenia. J Abnorm Psychol. 1989;98:341-356.
6. Newlin DB, Carpenter B, Golden CJ. Hemispheric asymmetries in schizophrenia. Biol Psychiatry. 1981;16:561-582.
7. Seidman L. Schizophrenia and brain dysfunction: an integration of recent neurodiagnostic findings. Psychol Bull. 1983;94:195-238.
8. Robertson G, Taylor PJ. Laterality and psychosis: neuropsychological evidence. Br Med Bull. 1987;43:634-650.
9. Goldstein K. The organismic approach. In: Arieti S, ed. American Handbook of Psychiatry. New York, NY: Basic Books Inc Publishers; 1959;2:1333-1347.
10. Grant DA, Berg EA. A behavioral analysis of degree of reinforcement and ease of shifting to new responses in a Weigltype card-sorting problem. J Exp Psychol. 1948;38:404-411.
11. Reitan RM, Wolfson D. The Halstead-Reitan Neuropsychological Test Battery: Theory and Clinical Interpretation. Tucson, Ariz: Neuropsychology Press; 1985.
12. Flor-Henry P, Yeudall LT. Neuropsychological investigations of schizophrenia and manic-depressive psychoses. In: Gruzelier J, Flor-Henry P, eds. Hemispheric Asymmetries of Function in Psychopathology. Amsterdam, the Netherlands: Elsevier/North Holland; 1979.
13. Heaton RK. Wisconsin Card Sorting Test, Manual. Odessa, Fla: Psychological Assessment Resources; 1981.
14. Goldberg TE, Weinberger DR, Berman KF, Pliskin NH, Podd MH. Further evidence for dementia of the prefrontal type in schizophrenia? Arch Gen Psychiatry. 1987;44:1008-1014.
15. Kraepelin E; Barclay E, Barclay S, trans. Dementia Praecox. New York, NY: Churchill Livingstone Inc; 1919.
16. Shakow D. Psychological deficit in schizophrenia. Behav Sci. 1963;8:275-305.
17. Mirsky AF. Behavioral and electrographic measures of attention in children at risk for schizophrenia. J Abnorm Psychol. 1977;86:27-33.
18. Mirsky AF. From Worcester to Haifa: fifty years of attention research in neuropsychiatry. Presented at the American Psychological Association meeting; August 1986; Washington, DC.
19. Schwartz S. Is there a schizophrenic language? Behav Brain Sci. 1982;5:579-626.
20. Andreasen NC, Grove W. The relationship between schizophrenic language, manic language and aphasia. In: Gruzelier J, Flor-Henry P, eds. Hemisphere Asymmetries in Function Psychopathology. Amsterdam, the Netherlands: Elsevier/North Holland; 1979.
21. Silverberg-Shalev R, Gordon HW, Bentin S, Aranson A. Selective language deterioration in chronic schizophrenia. J Neurol Neurosurg Psychiatry. 1981;44:547-551.
22. Koh SD. Remembering of verbal materials by schizophrenic young adults. In: Schwartz S, ed. Language and Cognition in Schizophrenia. Hillsdale, NJ: Lawrence Earlbaum; 1978:55-99.
23. CalevA, Venables PH, Monk AF. Evidencefor distinctverbal memory pathologies in severely and mildly disturbed schizophrenics. Schizophr Bull. 1983;9:247.
24. Sengel RA, Lovallo WR. Effects of cueing on immediate and recent memory in schizophrenics. J Nerv Ment Dis. 1983;171:426-430.
25. Calev A. Recall and recognition in chronic nondemented schizophrenics. J Abnorm Psychol. 1984;93:172-177.
26. Calev A, Berlin H, Lerer B. Remote and recent memory in long-hospitalized chronic schizophrenics. Biol Psychiatry. 1987;22:79-85.
27. Kolb B, Whishaw IQ. Performance of schizophrenic patients on tests sensitive to left or right frontal, temporal, or parietal function in neurological patients. J Nerv Ment Dis. 1983;171:435-443.
28. Calev A, Korin Y, Kugelmass S, Lerer B. Performance of chronic schizophrenics on matched word and design recall tasks. Biol Psychiatry. 1987;22:699-709.
29. Frith CD. Schizophrenia, memory and anticholinergic drugs. J Abnorm Psychol. 1984;98:341-356.
30. Spohn HE, Strauss ME. Relation of neuroleptic and anticholinergic medication to cognitive functions in schizophrenia. J Abnorm Psychol. 1989;98:367-380.
31. Mesulam M-M, ed. Principles of Behavioral Neurology. Philadelphia, Pa: FA Davis; 1985.
32. Flor-Henry P. Lateralized temporal-limbic dysfunction and psychopathology. Ann N Y Acad Sci. 1976;280:777-795.
33. Gur RE. Motoric laterality imbalance in schizophrenia. Arch Gen Psychiatry. 1977;34:33-37.
34. Gur RE. Left hemisphere dysfunction and left hemisphere overactivation in schizophrenia. J Abnorm Psychol. 1978; 87:226-238.
35. Weinberger DR, Berman KF, Zec RF. Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia, I: regional cerebral blood flow evidence. Arch Gen Psychiatry. 1986;43:114-125.
36. Stuss DT, Kaplan EF, Benson DF, Weir WS, Chiulli S, Sarazin FF. Evidence for the involvement of orbitofrontal cortex in memory functions: an interference effect. J Comp Physiol Psychol. 1982;96:913-925.
37. Milner B. Psychological aspects of focal epilepsy and its neurosurgical management. Adv Neurol. 1975;8:299-321.
38. Squire LR, Butters N. Neuropsychology of Memory. New York, NY: Guilford Press; 1984.
39. Signoret JL. Memory and amnesias. In: Mesulam M-M, ed. Principles of Behavioral Neurology. Philadelphia, Pa: FA Davis; 1985.
40. Chapman LJ, Chapman JP. The measurement of differential deficits. J Psychiatr Res. 1978;14:303-311.
41. Chapman LJ, Chapman JP. Strategies for resolving the heterogeneity of schizophrenics and their relatives using cognitive measures. J Abnorm Psychol. 1989;98:357-366.
42. Lord FM. Elementary models for measuring change. In: Harris CW, ed. Problems in Measuring Change. Madison, Wis: University of Wisconsin Press; 1963:21-38.
43. Lieberman JA, Bowers MB. Substance abuse comorbidity in schizophrenia: editor's introduction. Schizophr Bull. 1990;16:29-30.
44. Mueser KT, Yarnold PR, Levinson DF, Singh H, Bellack AS, Kee K, Morrison RL, Yadalam KG. Prevalence of substance abuse in schizophrenia: demographic and clinical correlates. Schizophr Bull. 1990;16:31-56.
45. Dohrenwend BP, Dohrenwend BS. Social Status and Psychological Disorder: A Causal Inquiry. New York, NY: John Wiley & Sons Inc; 1969.
46. Meehl PE. Nuisance variable and the ex post facto design. In: Radner M, Winokur S, eds. Minnesota Studies in the Philosophy of Science. Minneapolis, Minn: University of Minnesota Press; 1970:373-402.
47. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Revised Third Edition. Washington, DC: American Psychiatric Association; 1987.
48. Oldfield RC. The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia. 1971;9:97-113.
49. Spitzer RL, Williams JB, Gibbon M. Instruction Manual for the Structured Clinical Interview for DSM-III-R (SCID). New York, NY: Biometrics Research Department, New York State Psychiatric Institute; 1987.
50. Wechsler D. Wechsler Adult Intelligence Scale-Revised, Manual. Cleveland, Ohio: The Psychological Corp; 1981.
51. Wechsler D. A standardized memory scale for clinical use. J Psychol. 1945;19:87-95.
52. Russell EW. A multiple scoring method for assessment of complex memory functions. J Consult Clin Psychol. 1975; 43:800-809.
53. Gangarosa ME, Saykin AJ, Malamut BL, Gur RC. New scoring systems for Wechsler Memory Scale: inter-rater reliability. J Clin Exp Neuropsychol. 1988;10:1-43.
54. Delis DC, Kramer JH, Kaplan E, Ober BA. California Verbal Learning Test, Research Edition. Cleveland, Ohio: The Psychological Corp; 1983.
55. Benton AL, Hamsher K. Multilingual Aphasia Examination. Iowa City, Iowa: University of Iowa; 1976.
56. Goodglass H, Kaplan E. The Assessment of Aphasia and Related Disorders. 2nd ed. Philadelphia, Pa: Lea& Febiger; 1983.
57. Jastak S, Wilkinson GS. Wide Range Achievement Test-Revised, Manual. Wilmington, Del: Jastak Associates Inc, 1984.
58. Golden CJ. Stroop Color and Word Test: A Manual for Clinical and Experimental Uses. Chicago, III: Stoelting Co; 1978.
59. Golden CJ, Hammeke TA, Purisch AD. Luria-Nebraska Neuropsychological Battery, Manual. Los Angeles, Calif: Western Psychological Services; 1980.
60. Gordon M. Manual, Gordon Diagnostic System. New York, NY: Gordon Diagnostic Systems Inc; 1986.
61. Benton AL, Hamsher K, Varney N, Spreen O. Contributions to Neuropsychological Assessment: A Clinical Manual. New York, NY: Oxford University Press; 1983.
62. Heaton RK, Grant I, Matthews CG. Differences in neuropsychological test performance associated with age, education and sex. In: Grant I, Adams KM, eds. Neuropsychological Assessment of Neuropsychiatric Disorders. New York, NY: Oxford University Press; 1986.
63. SAS Institute Inc. SAS/STAT software, version 6.03. Cary, NC: SAS Institute Inc; 1987.
64. Goldstein G, Shelly C. Statistical and normative studies of the Halstead Neuropsychological Test Battery relevant to a neuropsychiatric hospital setting. Percept Mot Skills. 1972; 34:603.
65. Shelly C, Goldstein G. Psychometric relations between the Halstead-Reitan and Luria-Nebraska Neuropsychological Test Batteries in a neuropsychiatric setting. Clin Neuropsychol. 1982;4:128-133.
66. Swiercinsky DP, Howard ME. Programmatic series of factor analyses for evaluating the structure of neuropsychological test batteries. Clin Neuropsychol. 1983;4:147-152.
67. Ernst J, Warner MH, Hochberg M, Townes B. Factor analysis of the Halstead-Reitan Neuropsychological Battery including the WAIS and replications using the WAIS-R. Int J Clin Neuropsychol. 1988;10:103-105.
68. Shakow D. Segmental set: a theory of the formal psychological deficit in schizophrenia. Arch Gen Psychiatry. 1962;6:17-33.
69. McGhie A, Chapman J. Disorders of attention and perception in early schizophrenia. Br J Med Psychol. 1961;34:103-116.
70. Mirsky AF, Duncan CC. Etiology and expression of schizophrenia: neurobiological and psychosocial factors. Ann Rev Psychol. 1986;37:291-319.
71. Medalia A, Gold J, Merriam A. The effects of neuroleptics on neuropsychological test results of schizophrenics. Arch Clin Neuropsychol. 1988;3:249-271.
72. Carlin AS. Neuropsychological consequences of drug abuse. In: Grant I, Adams KM, eds. Neuropsychological Assessment of Neuropsychiatric Disorders. New York, NY: Oxford University Press; 1986.
73. Gur RE, Skolnick BE, Gur RC, Caroff S, Rieger W, Obrist WD, Younkin D, Reivich M. Regional brain function in psychiatric disorders, I: regional cerebral blood flow in medicated schizophrenics. Arch Gen Psychiatry. 1983;40:1250-1254.
74. Gur RE, Gur RC, Skolnick BE, Caroff S, Obrist WD, Resnick SM, Reivich M. Regional brain function in psychiatric disorders, III: regional cerebral blood flow in unmedicated schizophrenics. Arch Gen Psychiatry. 1983;42:329-334.
75. Gur RE, Resnick SM, Alavi A, Gur RC, Caroff S, Dann R, Silver F, Saykin AJ, Chawluk JB, Kushner M, Reivich M. Regional brain function in schizophrenia, I: a positron emission tomography study. Arch Gen Psychiatry. 1987;44:119-125.
76. Luria AR. The Neuropsychology of Memory. New York, NY: John Wiley & Sons Inc; 1976.
77. Janowsky JS, Shimamura AP, Kritchevsky M, Squire L. Cognitive impairment following frontal lobe damage and its relevance to human amnesia. Behav Neurosci. 1989;103:548-560.
78. Bemdt RS, Caramazza A, Zurif E. Language functions: syntax and semantics. In: Segalowitz H, ed. Language Functions and Brain Organization. Orlando, Fla: Academic Press Inc; 1983.
79. Jeste DV, Lohr JB. Hippocampal pathologic findings in schizophrenia: a morphometric study. Arch Gen Psychiatry. 1989;46:1019-1024.
80. Suddath RL, Casanova MF, Goldberg TE, Daniel DG, Kelsoe JR, Weinberger DR. Temporal lobe pathology in schizophrenia: a quantitative magnetic resonance imaging study. Am J Psychiatry. 1989;146:464-472.
81. McCarley RW, Faux SF, Shenton M, LeMay M, Cane M, Ballinger R, Duffy F. CT abnormalities in schizophrenia: a preliminary study of their correlations with P300/P200 electrophysiological features and positive/negative symptoms. Arch Gen Psychiatry. 1989;46:698-708.
82. Pfefferbaum A, Ford JM, White PM, Roth WT. p3 in schizophrenia is affected by stimulus modality, response requirements, medication status, and negative symptoms. Arch Gen Psychiatry. 1989;46:1035-1044.
83. Saykin AJ, Gur RC, Sussman NM, Gur RE. Memory deficits before and after temporal lobectomy: effect of laterality and age of onset. Brain Lang. 1989;9:191-200.
84. Gruzelier J, Seymour K, Wilson L, Jolley A, Hirsch S. Impairments on neuropsychological tests of temporohippocampal and fronto-hippocampal functions and word fluency in remitting schizophrenia and affective disorders. Arch Gen Psychiatry. 1988;45:623-629.