Probing the Mechanism and Improving the Rate of Substrate-Assisted Catalysis in Subtilisin BPN′

Biochemistry

Volumn 30, Issue 25, 1991, Pages 6142-6148

  Carter, Paul ^a   Abrahmsén, Lars ^a   Wells, Janies A ^a  

^a GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MUTANT ENZYME; SUBTILISIN; UNCLASSIFIED DRUG;

ARTICLE; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE; NONHUMAN; PRIORITY JOURNAL;

ACYLATION; BASE SEQUENCE; BINDING SITES; CATALYSIS; HYDROLYSIS; IMIDAZOLES; KINETICS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; SUBTILISINS;

EID: 0025874449     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi00239a009     Document Type: Article

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