Evaluation of the antimicrobial activity of methylglyoxal bis(guanylhydrazone) analogues, the inhibitors for polyamine biosynthetic pathway

Journal of Applied Bacteriology

Volumn 70, Issue 4, 1991, Pages 291-293

  Midorikawa, Y ^a   Hibasami, H ^b   Gasaluck, P ^a   Yoshimura, H ^a   Masuji, A ^a   Nakashima, K ^a   Imai, M ^a  

^a MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b MIE UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGUAZONE; POLYAMINE;

AEROMONAS; AEROMONAS HYDROPHILA; ANTIMICROBIAL ACTIVITY; ARTICLE; ESCHERICHIA COLI; NONHUMAN; POLYAMINE SYNTHESIS; SHIGELLA SONNEI; VIBRIO CHOLERAE;

BACTERIA; BACTERIAL PROTEINS; BIOGENIC POLYAMINES; ESCHERICHIA COLI; MITOGUAZONE;

AEROMONAS HYDROPHILA; AEROMONAS SOBRIA; ESCHERICHIA COLI; SHIGELLA SONNEI; VIBRIO CHOLERAE;

EID: 0025872945     PISSN: 00218847     EISSN: 13652672     Source Type: Journal    
DOI: 10.1111/j.1365-2672.1991.tb02938.x     Document Type: Article

References (16)

1. A putrescine‐requiring mutant of
2. Mutants of Escherichia coli that do not contain 1,4‐diaminobutane (putrescine) or spermidine
3. Putrescine as a growth factor for
4. Antitumor effect of methylglyoxal bis(butylamidinohydrazone), a new inhibitor of S‐adenosylmethionine decarboxylase
5. Methylglyoxal bis (butylamidinohydrazone), a new inhibitor of polyamine biosynthesis that simultaneously inhibits ornithine decarboxylase, adenosylmethionine decarboxylase and spermidine synthase
6. Antitumor effect of a new multienzyme inhibitor of polyamine synthetic pathway, methylglyoxal bis(cyclopentylamidinohydrazone), against human and mouse leukemia cells
7. Polyamines in rapid growth and cancer
8. Potential of ornithine decarboxylase inhibitors as therapeutic agents.
9. Induction of spermidine/spermine N'‐acetyltransferase in needle‐punctured rat lens as a model of traumatic cataract
10. Methylglyoxal bis(guanylhydrazone) analogs multifunctional inhibitors for polyamine enzymes
11. Inhibition of S‐adenosylmethionine decarboxylase as an approach in cancer therapeutics
12. Adenosylmethionine decarboxylase from various organisms: relation of the putrescine activation of the enzyme to the ability of the organism to synthesize spermine
13. Suicide enzyme inhibitors as potential drugs
14. Putrescine as an essential growth factor for a mutant of
15. Polyamines
16. Escherichia coli mutants completely deficient in adenosylmethioine decarboxylase and in spermidine biosynthesis