CD5+ B cells in autoimmune disease and lymphoid malignancy

Clinical Immunology and Immunopathology

Volumn 59, Issue 2, 1991, Pages 173-186

  Shirai, Toshikazu ^a   Hirose, Sachiko ^a   Okada, Takashi ^a   Nishimura, Hiroyuki ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; AUTOIMMUNITY; B LYMPHOCYTE; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; HUMAN; MOUSE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SHORT SURVEY; SJOEGREN SYNDROME; SYSTEMIC LUPUS ERYTHEMATOSUS;

EID: 0025869953     PISSN: 00901229     EISSN: None     Source Type: Journal    
DOI: 10.1016/0090-1229(91)90016-4     Document Type: Short Survey

References (80)

1. The “Ly-1 B” cell subpopulation in normal, immunodefective and autoimmune mice
2. Ly-1 B-cells: Functionally distinct lymphocytes that secrete IgM autoantibodies
3. Development and physiology of Ly-1 B and its human homolog, Leu-1 B
4. The Ly-1 B cell lineage
5. + (B′) cell in allotype-restricted antibody formation
6. Expression of Lyt-1 by a subset of B lymphocytes
7. Infrequent normal B lymphocytes express features of B-chronic lymphocytic leukemia
8. Phenotypic and functional characterization of human Leu 1 (CD5) B cells
9. Peritoneal Ly-1 B cells: Genetic control, autoantibody production, increased lambda light chain expression
10. Stable expression and somatic hypermutation of antibody V regions in B-cell developmental pathways
11. + B lymphocytes
12. + B lymphocytes, polyreactive antibodies and the human B-cell repertoire
13. + (CD5) B-cells that recognize phosphatidyl choline: Relationship to cells that secrete hemolytic antibody specific for autologous erythrocytes
14. Autoantibodies against mouse bromelain-modified RBC are specifically inhibited by a common membrane phospholipid, phosphatidylcholine
15. + B-cell are polyreactive
16. + B-cells upon transfer of peritoneal cells into allotype-congenic newborn mice
17. Changes in immunoglobulin class and subclass of anti-DNA antibodies with increasing age in NZB/W F1 hybrid mice
18. Immunological regulation of spontaneous antibodies to DNA and RNA. II. Sequential switch from IgM to IgG in NZB/NZW F1 mice
19. Genetic regulation of the class conversion of dsDNA-specific antibodies in (NZB × NZW) F1 hybrid
20. Immunologic regulation of spontaneous antibodies to DNA and RNA. I. Significance of IgM and IgG antibodies in SLE patients and asymptomatic relatives
21. Expression of Lyt-1 antigen on certain murine B-cell lymphoma
22. + lineage of B lymphocyte differentiation
23. Ly-1 as a differentiation antigen on normal and neoplastic B cells
24. Identification of a p69,71 complex expressed on human T-cells sharing determinants with B-type chronic lymphocytic leukemia cells
25. An antigen shared by a human T cell subset and B cell chronic lymphocytic leukemic cells
26. Human T-cell antigens defined by monoclonal antibodies: The 65,000-dalton antigen of T cells (T65) is also found on chronic lymphocytic leukemia cells bearing surface immunoglobulin
27. Interaction of rheumatoid factor with infectious herpes simplex virus-antibody complexes
28. Rheumatoid factor-like immunoglobulin M protects previously uninfected rat pups and dams from Trypanosoma lewisi
29. Polyspecific monoclonal autoantibodies reactive with both polynucleotides and phospholipids
30. Natural antibodies against tubulin, actin, myoglobin, thyroglobulin, fetuin, albumin and transferrin are present in normal human sera, and monoclonal immunoglobulinemia may express similar antibody specificities
31. Thirty-six human monoclonal immunoglobulins with antibody activity against cytoskeleton proteins, thyroglobulin and native DNA: Immunologic studies and clinical correlations
32. Murine hybridomas secreting natural monoclonal antibodies reacting with self antigens
33. Murine natural monoclonal autoantibodies: A study of their polyspecificities and their affinities
34. Origins of anti-DNA antibodies
35. Binding of cytoskeletal proteins by monoclonal anti-DNA lupus antibodies
36. A monoclonal anti-DNA antibody also binds to cell-surface protein(s)
37. Cross-reactivity of anti-DNA antibodies with proteoglycans
38. CBA/N X-linked B cell defect prevents NZB B-cell hyperactivity in F1 mice
39. Localization of spontaneously hyperactive B cells of NZB mice to a specific B cell subset
40. Study of congenitally immunologic mutant New Zealand mice. V. B cell function of NZB-Xid mice
41. T cell abnormalities in NZB mice occur independently of autoantibody production
42. + B cells
43. A rheumatoid arthritis B-cell subset expresses a phenotype similar to that in chronic lymphocytic leukemia
44. Evaluation of CD5 positive B-cells in blood and synovial fluid of patients with rheumatic diseases
45. + B cells in rheumatic diseases
46. − B cells in systemic lupus erythematosus patients
47. + and CD5 B cells of patients with systemic lupus erythematosus
48. Distinct surface phenotypes of B cells responsible for spontaneous production of IgM and IgG anti-DNA antibodies in autoimmuneprone NZB × NZW F1 mice
49. Ly-1 B-cell clones similar to human chronic lymphocytic leukemias routinely develop in older normal mice and young autoimmune (New Zealand Black-related) animals
50. Germline antibody V regions as determinants of clonal persistence and malignant growth in the B cell compartment
51. Biased immunoglobulin variable gene expression by Ly-1 B cells due to clonal selection
52. Demonstration of activation of B lymphocytes in New Zealand black mice at birth by an immunoradiometric assay for murine IgM
53. Increased spontaneous polyclonal activation of B lymphocytes in mice with spontaneous autoimmune disease
54. Polyclonal B cell activation and autoimmunity in New Zealand mice. I. Natural thymocytotoxic autoantibody (NTA)
55. Are Lyl B cells responsible for the IL2-hyperresponsiveness of B cells in autoimmune-prone NZB × NZW F1 mice?
56. The novel murine B cell differentiation antigen Lp-3
57. Interleukin 2 is a proliferative signal for B cells from autoimmune mice
58. B cell hyperresponsiveness to interleukin 2 and the age-associated decline in murine lupus
59. Cellular basis of in vitro anti-DNA antibody production: Evidence for T cell dependence of IgG-class anti-DNA antibody synthesis in the (NZB × NZW)F1 hybrid
60. Class-specific regulation of anti-DNA antibody synthesis and the age-associated changes in (NZB × NZW)F1 hybrid mice
61. Induction of a cationic shift in IgG anti-DNA autoantibodies: Role of T helper cells with classical and novel phenotypes in three murine models of lupus nephritis
62. Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors)
63. k gene directly encodes rheumatoid factor light chains
64. H gene segment of normal A/J mice encodes autoantibodies characteristic of systemic lupus erythematosus
65. Novel V genes encode virtually identical variable regions of six murine monoclonal anti-bromelain-treated red blood cell autoantibodies
66. The heavy chain genes of a lupus anti-DNA autoantibody are encoded in the germ line of a nonautoimmune strain of mouse and conserved in strains of mice polymorphic for the gene locus
67. Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). II. Comparison of hybridomas derived by lipopolysaccharide stimulation and secondary protein immunization
68. A natural autoantibody is encoded by germline heavy and lambda light chain variable region genes without somatic mutation
69. The role of clonal selection and somatic mutation in autoimmunity
70. Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse
71. H 11 germ-line gene that encodes the heavy-chain variable region of antibodies to double-stranded DNA in (NZB × NZW)F1 mice
72. Evolutionary and somatic selection of the repertoire in the mouse
73. + B-cell lymphoma
74. Genetic and cellular basis of anti-DNA antibody synthesis in systemic lupus erythematosus of New Zealand mice
75. Requirement of H-2 heterozygosity for autoimmunity in (NZB × NZW)F1 hybrid mice
76. Does the deletion within T cell receptor beta chain gene of NZW mice contribute to autoimmunity in (NZB × NZW)F1 mice?
77. Autoimmune disease of NZB/B1 mice. II. Autoimmunity and malignant lymphoma
78. Immunopathology and neoplasms in New Zealand Black (NZB) and SJL-J mice