-
1
-
-
7144248725
-
Plant antitumor agents. I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptothcca acuminata
-
Wall ME, Wani MC, Cook CE, et al: Plant antitumor agents. I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptothcca acuminata. J Am Chem Soc 88:3888–3890, 1966
-
(1966)
J am Chem Soc
, vol.88
, pp. 3888-3890
-
-
Wall, M.E.1
Wani, M.C.2
Cook, C.E.3
-
2
-
-
0022340594
-
Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I
-
Hsiang YH, Hertzberg R, Hecht S, et al: Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J Biol Chem 260:14873–14878, 1985
-
(1985)
J Biol Chem
, vol.260
, pp. 14873-14878
-
-
Hsiang, Y.H.1
Hertzberg, R.2
Hecht, S.3
-
3
-
-
0023395222
-
Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I
-
Proc Natl Acad Sci USA
-
Andoh T, Ishii K, Suzuki Y, et al: Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I. Proc Natl Acad Sci USA 84:5565–5569, 1987
-
(1987)
, vol.84
, pp. 5565-5569
-
-
Andoh, T.1
Ishii, K.2
Suzuki, Y.3
-
4
-
-
0015451631
-
Action of camptothecin on mammalian cells in culture
-
Li LH, Fraser TJ, Oun EJ, et al: Action of camptothecin on mammalian cells in culture. Cancer Res 32:2643–2650, 1972
-
(1972)
Cancer Res
, vol.32
, pp. 2643-2650
-
-
Li, L.H.1
Fraser, T.J.2
Oun, E.J.3
-
5
-
-
0016052023
-
Lethal activity of camptothecin sodium on human lymphoma cells
-
Drewinko B, Freireich EJ, Gottlieb JA: Lethal activity of camptothecin sodium on human lymphoma cells. Cancer Res 34:747–750, 1974
-
(1974)
Cancer Res
, vol.34
, pp. 747-750
-
-
Drewinko, B.1
Freireich, E.J.2
Gottlieb, J.A.3
-
6
-
-
0015044313
-
Studies on the antitumor activity, mechanism of action, and cell cycle effects of camptothecin
-
Gallo RC, Whang-Peno J, Adamson RH: Studies on the antitumor activity, mechanism of action, and cell cycle effects of camptothecin. J Natl Cancer Inst 46:789–795, 1971
-
(1971)
J Natl Cancer Inst
, vol.46
, pp. 789-795
-
-
Gallo, R.C.1
Whang-Peno, J.2
Adamson, R.H.3
-
7
-
-
0014895176
-
Preliminary pharmacologic and clinical evaluation of camptothecin sodium (NSC-100880)
-
Gottueb JA, Guarino AM, Call JB, et al: Preliminary pharmacologic and clinical evaluation of camptothecin sodium (NSC-100880). Cancer Chemother Rep 54:461–470, 1970
-
(1970)
Cancer Chemother Rep
, vol.54
, pp. 461-470
-
-
Gottueb, J.A.1
Guarino, A.M.2
Call, J.B.3
-
8
-
-
0015378084
-
Phase I clinical trial of weekly and daily treatment with camptothecin (NSC-100880): Correlation with preclinical studies
-
Muogia FM, Creaven PJ, Hansen HH, et al: Phase I clinical trial of weekly and daily treatment with camptothecin (NSC-100880): Correlation with preclinical studies. Cancer Chemother Rep 56:515–521, 1972
-
(1972)
Cancer Chemother Rep
, vol.56
, pp. 515-521
-
-
Muogia, F.M.1
Creaven, P.J.2
Hansen, H.H.3
-
9
-
-
0015291595
-
Phase n study of camptothecin (NSC-100880) in the treatment of advanced gastrointestinal cancer
-
Moertel CG, Schutt AJ, Reitemeier RJ, et al: Phase n study of camptothecin (NSC-100880) in the treatment of advanced gastrointestinal cancer. Cancer Chemother Rep 56:95–101, 1972
-
(1972)
Cancer Chemother Rep
, vol.56
, pp. 95-101
-
-
Moertel, C.G.1
Schutt, A.J.2
Reitemeier, R.J.3
-
10
-
-
0015292126
-
Treatment of malignant melanoma with camptothecin (NSC-100880)
-
Gottueb JA, Luce JK: Treatment of malignant melanoma with camptothecin (NSC-100880). Cancer Chemother Rep 56:103–105, 1972
-
(1972)
Cancer Chemother Rep
, vol.56
, pp. 103-105
-
-
Gottueb, J.A.1
Luce, J.K.2
-
11
-
-
0015407723
-
Plasma camptothecin (NSC-100880) levels during a 5-day course of treatment: Relation to dose and toxicity
-
Creaven PJ, Allen LM, Muggia FM: Plasma camptothecin (NSC-100880) levels during a 5-day course of treatment: Relation to dose and toxicity. Cancer Chemother Rep 56:573–578, 1972
-
(1972)
Cancer Chemother Rep
, vol.56
, pp. 573-578
-
-
Creaven, P.J.1
Allen, L.M.2
Muggia, F.M.3
-
12
-
-
0019207756
-
Distribution and excretion of 10-hydroxycamptothecin and its influence on immune response
-
Yang J, Han J, Xu B: Distribution and excretion of 10-hydroxycamptothecin and its influence on immune response. Acta Pharmacol Sin 1:44–48, 1980
-
(1980)
Acta Pharmacol Sin
, vol.1
, pp. 44-48
-
-
Yang, J.1
Han, J.2
Xu, B.3
-
13
-
-
0020522548
-
Action of (S)-10-hydroxycamptothecin on P388 leukemia and distribution of the drug in mice
-
Creasey WA, Richards M, Gil D, et al: Action of (S)-10-hydroxycamptothecin on P388 leukemia and distribution of the drug in mice. Cancer Treat Rep 67:179–182, 1983
-
(1983)
Cancer Treat Rep
, vol.67
, pp. 179-182
-
-
Creasey, W.A.1
Richards, M.2
Gil, D.3
-
14
-
-
0023243513
-
Action of 7-ethylcamptothecin on tumor cells and its disposition in mice
-
Nagata H, Kaneda N, Furuta T, et al: Action of 7-ethylcamptothecin on tumor cells and its disposition in mice. Cancer Treat Rep 71:341–348, 1987
-
(1987)
Cancer Treat Rep
, vol.71
, pp. 341-348
-
-
Nagata, H.1
Kaneda, N.2
Furuta, T.3
-
15
-
-
0023280232
-
Antitumor activity of a new camptothecin derivative, SN-22, against various murine tumors
-
Kunimoto T, Nitta K, Tanaka T, et al: Antitumor activity of a new camptothecin derivative, SN-22, against various murine tumors. J Pharmacobiodyn 10:148–151, 1987
-
(1987)
J Pharmacobiodyn
, vol.10
, pp. 148-151
-
-
Kunimoto, T.1
Nitta, K.2
Tanaka, T.3
-
16
-
-
0023552964
-
Antitumor activity of 7-ethyl-10-[4-(L-piperidino)-1-piperidino]carbonyloxy-camptothecin, a novel water-soluble derivative of camptothecin, against murine tumors
-
Kunimoto T, Nitta K, Tanaka T, et al: Antitumor activity of 7-ethyl-10-[4-(l-piperidino)-1-piperidino]carbonyloxy-camptothecin, a novel water-soluble derivative of camptothecin, against murine tumors. Cancer Res 47:5944–5947, 1987
-
(1987)
Cancer Res
, vol.47
, pp. 5944-5947
-
-
Kunimoto, T.1
Nitta, K.2
Tanaka, T.3
-
17
-
-
0023904035
-
Inhibition of spontaneous and experimental metastasis by a new derivative of camptothecin, CPT-11, in mice
-
Matsuzaki T, Yokokura T, Mutai M, et al: Inhibition of spontaneous and experimental metastasis by a new derivative of camptothecin, CPT-11, in mice. Cancer Chemother Pharmacol 21:308–312, 1988
-
(1988)
Cancer Chemother Pharmacol
, vol.21
, pp. 308-312
-
-
Matsuzaki, T.1
Yokokura, T.2
Mutai, M.3
-
18
-
-
0025266608
-
Phase I clinical study of CPT-11. Research group of CPT-11
-
Taguchi T, Wakui A, Hasegawa K, et al: Phase I clinical study of CPT-11. Research group of CPT-11. Gan To Kagaku Ryoho 17:115–120, 1990
-
(1990)
Gan to Kagaku Ryoho
, vol.17
, pp. 115-120
-
-
Taguchi, T.1
Wakui, A.2
Hasegawa, K.3
-
19
-
-
0025129894
-
An early phase n study of CPT-11: A new derivative of camptothecin, for the treatment of leukemia and lymphoma
-
Ohno R, Okada K, Masaoka T, et al An early phase n study of CPT-11: A new derivative of camptothecin, for the treatment of leukemia and lymphoma. J Clin Oncol 8:1907–1912, 1990
-
(1990)
J Clin Oncol
, vol.8
, pp. 1907-1912
-
-
Ohno, R.1
Okada, K.2
Masaoka, T.3
-
20
-
-
0023554687
-
Flow cytometric analysis of the effect of an antitumor alkaloid, camptothecin on cell cycle progression of KB cell
-
Nagata H: Flow cytometric analysis of the effect of an antitumor alkaloid, camptothecin on cell cycle progression of KB cell. J Aichi Med Univ Assoc 15:683–699, 1987
-
(1987)
J Aichi Med Univ Assoc
, vol.15
, pp. 683-699
-
-
Nagata, H.1
-
21
-
-
0025366634
-
Effect of administration schedules on the antitumor activity of CPT-11, a camptothecin derivative
-
Furuta T, Yokokura T: Effect of administration schedules on the antitumor activity of CPT-11, a camptothecin derivative. Gan To Kagaku Ryoho 17:121-130, 1990
-
(1990)
Gan to Kagaku Ryoho
, vol.17
, pp. 121-130
-
-
Furuta, T.1
Yokokura, T.2
-
22
-
-
0019365237
-
Reporting results of cancer treatment
-
Miller AB, Hoogstraten B, Staquet M, et al: Reporting results of cancer treatment. Cancer 47:207–214, 1981
-
(1981)
Cancer
, vol.47
, pp. 207-214
-
-
Miller, A.B.1
Hoogstraten, B.2
Staquet, M.3
-
23
-
-
0025272187
-
Metabolism and pharmacokinetics of the camptothecin analogue CPT-11 in the mouse
-
Kaneda N, Nagata H, Furuta T, et al: Metabolism and pharmacokinetics of the camptothecin analogue CPT-11 in the mouse. Cancer Res 50:1715–1720, 1990
-
(1990)
Cancer Res
, vol.50
, pp. 1715-1720
-
-
Kaneda, N.1
Nagata, H.2
Furuta, T.3
-
24
-
-
0025342506
-
Nonlinear pharmacokinetics of CPT-11 in rats
-
Kaneda N, Yokokura T: Nonlinear pharmacokinetics of CPT-11 in rats. Cancer Res 50:1721–1725, 1990
-
(1990)
Cancer Res
, vol.50
, pp. 1721-1725
-
-
Kaneda, N.1
Yokokura, T.2
|