A possible procedure for reducing the immunogenicity of antibody variable domains while preserving their ligand-binding properties

Molecular Immunology

Volumn 28, Issue 4-5, 1991, Pages 489-498

  Padlan, Eduardo A ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIBODY; ANTIBODY;

ANIMAL TISSUE; ARTICLE; HUMAN; HUMAN TISSUE; IMMUNOGENICITY; IMMUNOGLOBULIN VARIABLE REGION; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMAL; ANTIBODIES, ANTI-IDIOTYPIC; BINDING SITES, ANTIBODY; COMPARATIVE STUDY; HUMAN; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOGLOBULINS, HEAVY-CHAIN; IMMUNOGLOBULINS, LIGHT-CHAIN; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; SOLVENTS; SPECIES SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA; MURINAE;

EID: 0025848797     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/0161-5890(91)90163-E     Document Type: Article

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