A tobacco smoke-derived nitrosamine, 4-(methytnitrosamino)-1-(3-pyridyl)-1-butanone, is activated by multiple human cytocbrome p450s including the polymorphic human cytochrome p4502d6

Carcinogenesis

Volumn 12, Issue 7, 1991, Pages 1197-1201

  Crespi, Charles L ^a   Penman, Bruce W ^a   Gelboin, Harry V ^a,b   Gonzalez, Frank J ^a,b  

^a Gentest Corporation   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CYTOCHROME P450; NITROSAMINE;

ARTICLE; B LYMPHOBLAST; CELL LINE; LUNG CANCER; MICROSOME; MUTAGENICITY; PRIORITY JOURNAL; SMOKING;

BIOTRANSFORMATION; CARCINOGENS; CELL LINE; CYTOCHROME P-450 ENZYME SYSTEM; DIMETHYLNITROSAMINE; HUMAN; ISOENZYMES; MIXED FUNCTION OXYGENASES; MUTAGENS; NITROSAMINES; SUPPORT, U.S. GOV'T, P.H.S.; TRANSFECTION;

EID: 0025848338     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/12.7.1197     Document Type: Article

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