Low growth hormone levels are related to increased body mass index and do not reflect impaired growth in luteinizing hormone-releasing hormone agonist-treated children with precocious puberty

Journal of Clinical Endocrinology and Metabolism

Volumn 72, Issue 2, 1991, Pages 301-307

  Kamp, Gerdine A ^a,b   Manasco, Penelope K ^b   Barnes, Kevin M ^a,b   Jones, Janet ^a   Rose, Susan R ^a,b   Hill, Suvimol C ^a   Cutler, Gordon B ^a,b  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ETHINYLESTRADIOL; GONADORELIN DERIVATIVE; GROWTH HORMONE;

ADOLESCENT; ARTICLE; BODY WEIGHT; CHILD; CONTROLLED STUDY; FEMALE; GROWTH RATE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRECOCIOUS PUBERTY; PRIORITY JOURNAL;

ADOLESCENT; AGE DETERMINATION BY SKELETON; ARGININE; BODY HEIGHT; BODY MASS INDEX; CHILD; CHILD, PRESCHOOL; CIRCADIAN RHYTHM; FEMALE; GONADORELIN; GROWTH; GROWTH HORMONE; HUMAN; INSULIN; LEVODOPA; MALE; PUBERTY, PRECOCIOUS; SUPPORT, NON-U.S. GOV'T;

EID: 0025845741     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jcem-72-2-301     Document Type: Article

References (39)

1. Comité F, Cassorla F, Barnes KM, et al. Luteinizing hormone releasing hormone analogue therapy for central precocious puberty: long-term effect on somatic growth, bone maturation, and predicted height. JAMA. 1986;255:2613-2616
2. Mansfield MJ, Rudlin CR, Crigler JF, et al. Changes in growth and serum growth hormone and plasma somatomedin-C levels during suppression of gonac al sex steroid secretion in girls with central precocious puberty. J Clin Endocrinol Metab. 1988;66:3-9.
3. Stanhope R, Pringle PJ, Brook CGD. Growth, growth hormone and sex steroid secretion in girls with central precocious puberty treated with a gonadotrophin releasing hormone (GnRH) analogue. Acta Paediatr Scand. 1988;77:525-30.
4. Odink RJH, Delemarre-van cle Waal HA, Herdes E, Salomon RHP. Gonadotropin and growth hormone secretion during treatment with a GnRH analog in 2 girls with central precocious puberty [Abstract 33]. Proc of thee 3rd Int Conf on the Control of the Onset of Puberty. 1989.
5. DiMartino-Nardi J, Patel U, Wu R, Sobel EH, Saenger P. LHRH analogue treatment for precocious puberty lowers nocturnal growth hormone levels [Abstract 482]. Pediatr Res. 1989;25:83.
6. Abe K, Matsuura N. Impaired GH secretion due to prolonged treatment with cyproterone acetate. Endocrinol Jpn. 1982;29:27-9.
7. Sklar C, Rothenberg S, Blumberg D, Oberfield S, Levine L, David R. Suppression of gonadal s ex steroids in central precocious puberty (CPP): effect on growth, growth hormone (GH) and prolactin (PRL) secretion [Abstract 230]. Horm Res. 1989;31:58.
8. Mansfield MJ, Beardsworth DE, Loughlin JS, et al. Long-term treatment of central precocious puberty with a long-acting analogue of luteinizing hormone-releasing hormone: effects on somatic growth and skeletal maturation. N Engl J Med. 1983;309:1286-90.
9. Manasco PK, Pescovitz OH, Hill SC, et al. Six-year results of luteinizing hormone releasing hormone (LHRH) agonist treatment in children with LHRH-dependent precocious puberty. J Pediatr. 1989;115;105-8.
10. Boepple PA, Mansfield MJ, Wierman ME, et al. Use of a potent, long acting agonist of gonadotropin-releasing hormone in treatment of precocious puberty. Endocr Rev. 1986;7:24-33.
11. Ross JL, Pescovitz OH, Barnes K, Loriaux DL, Cutler Jr GB. Growth hormone secretory dynamics in children with precocious puberty. J Pediatr. 1987;110:369-72.
12. Pescovitz OH, Comité F, Hench K, et al. The NIH experience with precocious puberty: diagnostic subgroups and response to shortterm luteinizing hormone releasing hormone analogue therapy. J Pediatr. 1986;108:47-54.
13. Pescovitz OH, Cutler Jr GE, Loriaux DL. Management of precocious puberty. J Pediatr Endocrinol. 1985;1:85-94.
14. Frasier SD. A review of growth hormone stimulation tests in children. Pediatrics. 1974;53:929-37.
15. Moll Jr G, Rosenfield RC, Fang VS. Administration of low-dose estrogen rapidly and directly stimulates growth hormone production. Am J Dis Child. 1986;140:124-7.
16. Gourmelen M, Pham-Huu-Trung MT, Girard F. Transient partial hGH deficiency in prepubertal children with delay of growth. Pediatr Res. 1979;13:221-4.
17. Rose SR, Ross JL, Uriarte M, Barnes KM, Cassorla FG, Cutler Jr GB. The advantage of measuring stimulated as compared with spontaneous growth hormone levels in the diagnosis of growth hormone deficiency. N Engl J Med. 1988;319:201-7.
18. Rose SR, Uriarte MM, Barnes KM, Ross JL, Cassorla F, Cutler Jr GB. Spontaneous growth hormone secretion in normal puberty [Abstract 10]. Proc of the 8th Int Congr of Endocrinol. 1988.
19. Cameron N. The methods of auxological anthropometry. In: Falkner F, Tanner JM, eds. Human growth: a comprehensive treatise, 2nd ed. New York: Plenum Press; 1986;3:3-46.
20. Greulich WW, Pyle SI. Radiographic atlas of skeletal development of the hand and wrist, 2nd ed. Stanford: Stanford University Press; 1959.
21. Tanner JM, Davis PSW. Clinical longitudinal standards for height and height velocity for North American children. J Pediatr. 1985;107:317-29.
22. Zachmann M, Sobradillo B, Frank M, et al. Bayley-Pinnau, Roch-Wainer-Thissen, and Tanner height predictions in normal children and in patients with various pathologic conditions. J Pediatr. 1978;93:749-55.
23. Najjar MF, Rowland M. National Center of Health Statistics: anthropometric reference data and prevalence of overweight, United States, 1976-80. Vital and Health Statistics, ser 11, no. 238. DHHS publication (PHS) 87-1688. Washington DC: USPHS.
24. Rolland-Cachera MF, Sempé M, Guilloud-Bataille M, Patois E, Péquignot-Guggenbuhl F, Fautrad V. Adiposity indices in children. Am J Clin Nutr. 1982:36:178-84.
25. Odell WD, Rayford PL, Ross GT. Simplified, partially automated method for radioimmunoassay of human thyroid-stimulating, growth, luteinizing, and follicle stimulating hormones. J Lab Clin Med. 1967;70:973-80.
26. Snedecor GW, Cochran WG. Statistical methods, 7th ed. Ames: Iowa State University Press; 1987;56-9.
27. Costin G. Effects of low-dose cranial radiation on growth hormone secretory dynamics and hypothalamic-pituitary function. Am J Dis Child. 1988;142:847-52.
28. Rappaport R, Brauner R. Growth and endocrine disorders secondary to cranial irradiation. Pediatr Res. 1989;25:561-7.
29. Martin JB, Reichlin S. Clinical neuroendocrinology, 2nd ed. Philadelphia: Davis; 1987.
30. Williams T, Berelowitz M, Joffe SN, et al. Impaired growth hormone responses to growth hormone-releasing factor in obesity. N Engl J Med. 1984;311:1403-7.
31. Kopelman PG, Noonan K, Goulton R, Forrest AJ. Impaired growth hormone response to growth hormone releasing factor and insulin-induced hypoglycaemia. Clin Endocrinol (Oxf). 1985;23:87-94.
32. Quabbe HJ, Helge H, Kubicki S. Nocturnal growth hormone secretion: correlation with sleeping EEG in adults and pattern in children and adolescents with non pituitary dwarfism, overgrowth with obesity. Acta Endocrinol (Copenh). 1971;67:767-83.
33. Laurian L, Oberman Z, Hoerer E, Wiznitzer T, Harrell A. Growth hormone responses to L-dopa in the thinned obese. Isr J Med Sci. 1982;120:624-8.
34. Bercu BB, Shulman DI, Root AW. Obesity decreases endogenous growth hormone (GH) secretion in children with normal growth velocities [Abstract 428]. Pediatr Res. 1988;23:272.
35. Loche S, Cappa M, Borreli P, et al. Reduced growth hormone response to growth hormone-releasing hormone in children with simple obesity: evidence for somatomedin-C midiated inhibition. Clin Endocinol (Oxf). 1987;27:145-53.
36. Cordido F, Casanueva FF, Dieguez C. Cholinergic receptor activation by pyridostigmine restores growth hormone (GH) responsiveness to GH-releasing hormone administration in obese subjects: evidence for hypothalamic somatostatinergic participation in the blunted GH release of obesity. J Clin Endocrinol Metab. 1989;68:290-3.
37. Cara JF, Burstein S, Cutler L, Moll Jr GW, Rosenfield RL. Growth hormone deficiency impedes the rise in plasma insulin-like growth factor 1 levels associated with precocious puberty. J Pediatr. 1989:115:64-8.
38. Attie KM, Nelson RR, Conte FA, Kaplan SL, Grumbach MM. Growth pattern in precocious puberty with growth hormone deficiency [Abstract 427]. Pediatr Res. 1988;23:272.
39. Manasco PK, Pescovitz OH, Feuillan PP, et al. Resumption of puberty after long term luteinizing hormone-releasing hormone agonist treatment of central precocious puberty. J Clin Endocrinol Metab. 1988;67:368-72.