-
1
-
-
0024722750
-
Towards generating cytotoxic agents at cancer sites
-
BAGSHAWE, K.D. (1989). Towards generating cytotoxic agents at cancer sites. Br. J. Cancer, 60, 275
-
(1989)
Br. J. Cancer
, vol.60
, pp. 275
-
-
Bagshawe, K.D.1
-
2
-
-
0024265081
-
Comparison of the pharmacokinetics and hepatotoxic effects of saporin and ricin A chain immunotoxins on murine liver parency- mal cells
-
BLAKEY, D C., SKILLETER, D.N., PRICE, R.J. & 4 others (1988a). Comparison of the pharmacokinetics and hepatotoxic effects of saporin and ricin A chain immunotoxins on murine liver parency- mal cells. Cancer Res., 48, 7072
-
(1988)
Cancer Res.
, vol.48
, pp. 7072
-
-
Blakey, D.C.1
Skilleter, D.N.2
Price, R.J.3
-
3
-
-
0023724114
-
Antibody-toxin conjugates: A perspective
-
Waldmann, H.Prog. Allergy, Karger: Basel
-
BLAKEY, D C., WAWRZYNCZAK, E.J., WALLACE, P.M. & THORPE, P.E. (1988b). Antibody-toxin conjugates: a perspective. In Monoclonal Antibody Therapy, Waldmann, H. (ed.) Prog. Allergy, Vol. 45, p. 50, Karger: Basel
-
(1988)
Monoclonal Antibody Therapy
, vol.45
, pp. 50
-
-
Blakey, D.C.1
Wawrzynczak, E.J.2
Wallace, P.M.3
Thorpe, P.E.4
-
4
-
-
0024950443
-
Realizing the full potential of immunotoxins
-
BLATTLER, W.A., LAMBERT, J.M. & GOLDMACHER, V.S. (1989). Realizing the full potential of immunotoxins. Cancer Cells, 1, 50
-
(1989)
Cancer Cells
, vol.1
, pp. 50
-
-
Blattler, W.A.1
Lambert, J.M.2
Goldmacher, V.S.3
-
5
-
-
85005061188
-
Intraperitoneal immunotoxin therapy: Two clinical studies. Antibody Immunoconj
-
BOOKMAN, M.A., FITZGERALD, D., FRANKEL, A. & 12 others (1990a). Intraperitoneal immunotoxin therapy: two clinical studies. Antibody Immunoconj. Radiopharm., 3, 70
-
(1990)
Radiopharm.
, vol.3
, pp. 70
-
-
Bookman, M.A.1
Fitzgerald, D.2
Frankel, A.3
-
6
-
-
79959683596
-
Antitransferrin receptor immunotoxin therapy: Phase I intraperitoneal trial
-
BOOKMAN, M.A., GODFREY, C., PADAVIC, H. & 5 others (1990b). Antitransferrin receptor immunotoxin therapy: phase I intraperitoneal trial. Proc. Annu. Meet. Am. Soc. Clin. Oncol., 9, 187
-
(1990)
Proc. Annu. Meet. Am. Soc. Clin. Oncol.
, vol.9
, pp. 187
-
-
Bookman, M.A.1
Godfrey, C.2
Padavic, H.3
-
7
-
-
0024437058
-
Phase I study of monoclonal antibody-ricin A chain immunotoxin XomaZyme-791 in patients with metastatic colon cancer
-
BYERS, V.S., RODVIEN, R., GRANT, H. & 4 others (1989). Phase I study of monoclonal antibody-ricin A chain immunotoxin XomaZyme-791 in patients with metastatic colon cancer. Cancer Res., 49, 6153
-
(1989)
Cancer Res.
, vol.49
, pp. 6153
-
-
Byers, V.S.1
Rodvien, R.2
Grant, H.3
-
8
-
-
0025647893
-
A recombinant single-chain immunotoxin composed of anti-Tac variable regions and a truncated diphtheria toxin
-
CHAUDHARY, V.K., GALLO, M.G., FITZGERALD, D.J. & PASTAN, I. (1990a). A recombinant single-chain immunotoxin composed of anti-Tac variable regions and a truncated diphtheria toxin. Proc. Natl Acad. Sci. USA, 87, 9491
-
(1990)
Proc. Natl Acad. Sci. USA
, vol.87
, pp. 9491
-
-
Chaudhary, V.K.1
Gallo, M.G.2
Fitzgerald, D.J.3
Pastan, I.4
-
9
-
-
0025012987
-
Pseudomonas exotoxin contains a specific sequence at the carboxyl terminus that is required for cytotoxicity
-
CHAUDHARY, V.K., JINNO, Y., FITZGERALD, D. & Pastan I. (1990b). Pseudomonas exotoxin contains a specific sequence at the carboxyl terminus that is required for cytotoxicity. Proc. Natl Acad. Sci. USA, 87, 308
-
(1990)
Proc. Natl Acad. Sci. USA
, vol.87
, pp. 308
-
-
Chaudhary, V.K.1
Jinno, Y.2
Fitzgerald, D.3
Pastan, I.4
-
10
-
-
0025184862
-
Mutagenesis of Pseudomonas exotoxin in identification of sequences responsible for animal toxicity
-
CHAUDHARY, V.K., JINNO, Y., GALLO, M.G., FITZGERALD, D. & PASTAN, I. (1990c). Mutagenesis of Pseudomonas exotoxin in identification of sequences responsible for animal toxicity. J. Biol. Chem., 265, 16306
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 16306
-
-
Chaudhary, V.K.1
Jinno, Y.2
Gallo, M.G.3
Fitzgerald, D.4
Pastan, I.5
-
11
-
-
0024349836
-
A recombinant immunotoxin consisting of two antibody variable domains fused to Pseudomonas exotoxin
-
CHAUDHARY, V.K., QUEEN, C., JUNGHANS, R.P., WALDMANN, T.A., FITZGERALD, D.J. & PASTAN, I. (1989). A recombinant immunotoxin consisting of two antibody variable domains fused to Pseudomonas exotoxin. Nature, 339, 394
-
(1989)
Nature
, vol.339
, pp. 394
-
-
Chaudhary, V.K.1
Queen, C.2
Junghans, R.P.3
Waldmann, T.A.4
Fitzgerald, D.J.5
Pastan, I.6
-
12
-
-
0025363534
-
Carrier protein-monensin conjugates: Enhancement of immunotoxin cytotoxicity and potentiation in tumor treatment
-
COLOMBATTI, M., Dell’arciprete, L., Chignola, R. & Tridente, G. (1990). Carrier protein-monensin conjugates: enhancement of immunotoxin cytotoxicity and potentiation in tumor treatment. Cancer Res., 50, 1385
-
(1990)
Cancer Res.
, vol.50
, pp. 1385
-
-
Colombatti, M.1
Dell’arciprete, L.2
Chignola, R.3
Tridente, G.4
-
13
-
-
0024476964
-
The Aspergillus toxin restrictocin is a suitable cytotoxic agent for the generation of immunoconjugates with monoclonal antibodies directed against human carcinoma cells
-
CONDE, F.P., ORLANDI, R., CANEVARI, S. & 5 others (1989). The Aspergillus toxin restrictocin is a suitable cytotoxic agent for the generation of immunoconjugates with monoclonal antibodies directed against human carcinoma cells. Eur. J. Biochem., 178, 795
-
(1989)
Eur. J. Biochem.
, vol.178
, pp. 795
-
-
Conde, F.P.1
Orlandi, R.2
Canevari, S.3
-
14
-
-
0024536758
-
Humoral immune responses to XMMCO-791-RTA immunotoxin in colorectal cancer patients
-
DURRANT, L.G., BYERS, V.S., SCANNON, P.J. & 5 others (1989). Humoral immune responses to XMMCO-791-RTA immunotoxin in colorectal cancer patients. Clin. Exp. Immunol., 75, 258
-
(1989)
Clin. Exp. Immunol.
, vol.75
, pp. 258
-
-
Durrant, L.G.1
Byers, V.S.2
Scannon, P.J.3
-
15
-
-
0023158579
-
Drug-targeting by monoclonal antibodies
-
EMBLETON, M.J. (1987). Drug-targeting by monoclonal antibodies. Br. J. Cancer, 55, 227
-
(1987)
Br. J. Cancer
, vol.55
, pp. 227
-
-
Embleton, M.J.1
-
16
-
-
0025328975
-
Antitumor effects of ricin A chain immunotoxins prepared from intact antibodies and Fab' fragments on solid human Hodgkin’s disease tumors in mice
-
ENGERT, A., MARTIN, G., PFREUNDSCHUH, M. & 4 others (1990). Antitumor effects of ricin A chain immunotoxins prepared from intact antibodies and Fab' fragments on solid human Hodgkin’s disease tumors in mice. Cancer Res., 50, 2929
-
(1990)
Cancer Res.
, vol.50
, pp. 2929
-
-
Engert, A.1
Martin, G.2
Pfreundschuh, M.3
-
17
-
-
0024603440
-
Monoclonal antibodies for imaging and therapy
-
EPENETOS, A.A. & KOSMAS, C. (1989). Monoclonal antibodies for imaging and therapy. Br. J. Cancer, 59, 152
-
(1989)
Br. J. Cancer
, vol.59
, pp. 152
-
-
Epenetos, A.A.1
Kosmas, C.2
-
18
-
-
0024426607
-
Targeted toxin therapy for the treatment of cancer
-
FITZGERALD, D. & PASTAN, I. (1989). Targeted toxin therapy for the treatment of cancer. J. Natl Cancer Inst., 81, 1455
-
(1989)
J. Natl Cancer Inst.
, vol.81
, pp. 1455
-
-
Fitzgerald, D.1
Pastan, I.2
-
20
-
-
0023890377
-
Pharmacokinetics of tumor-reactive immunotoxins in tumorbearing mice: Effect of antibody valency and deglycosylation of the ricin A chain on clearance and tumor localization
-
FULTON, R.J., TUCKER, T.F., VITETTA, E.S. & UHR, J.W. (1988a). Pharmacokinetics of tumor-reactive immunotoxins in tumorbearing mice: effect of antibody valency and deglycosylation of the ricin A chain on clearance and tumor localization. Cancer Res., 48, 2618
-
(1988)
Cancer Res.
, vol.48
, pp. 2618
-
-
Fulton, R.J.1
Tucker, T.F.2
Vitetta, E.S.3
Uhr, J.W.4
-
21
-
-
0023818404
-
Vivo therapy of the BCL1 tumor: Effect of immunotoxin valency and deglycosylation of the ricin A chain
-
1 tumor: effect of immunotoxin valency and deglycosylation of the ricin A chain. Cancer Res., 48, 2626
-
(1988)
Cancer Res
, vol.48
, pp. 2626
-
-
Fulton, R.J.1
Uhr, J.W.2
Vitetta, E.S.3
-
22
-
-
0023886893
-
Evaluation of ricin A chain-containing immunotoxins directed against CD 19 and CD22 antigens on normal and malignant human B cells as potential reagents for in vivo therapy
-
GHETIE, M.-A., MAY, R.D., TILL, M. & 10 others (1988). Evaluation of ricin A chain-containing immunotoxins directed against CD 19 and CD22 antigens on normal and malignant human B cells as potential reagents for in vivo therapy. Cancer Res., 48, 2610
-
(1988)
Cancer Res.
, vol.48
, pp. 2610
-
-
Ghetie, M.-A.1
May, R.D.2
Till, M.3
-
23
-
-
0025726426
-
Covalent binding of human α2-macroglobulin to deglycosylated ricin A chain and its immunotoxins
-
2-macroglobulin to deglycosylated ricin A chain and its immunotoxins. Cancer Res., 51, 1482
-
(1991)
Cancer Res.
, vol.51
, pp. 1482
-
-
Ghetie, M.-A.1
Uhr, J.W.2
Vitetta, E.S.3
-
24
-
-
0024411071
-
Phase I study of an anti-breast cancer immunotoxin by continuous infusion: Report of a targeted toxic effect not predicted by animal studies
-
GOULD, B.J., BOROWITZ, M.J., GROVES, E.S. & 4 others (1989). Phase I study of an anti-breast cancer immunotoxin by continuous infusion: report of a targeted toxic effect not predicted by animal studies. J. Natl Cancer Inst., 81, 775
-
(1989)
J. Natl Cancer Inst.
, vol.81
, pp. 775
-
-
Gould, B.J.1
Borowitz, M.J.2
Groves, E.S.3
-
25
-
-
0024849184
-
Immunotoxins: A clinical review of their use in the treatment of malignancies
-
HERTLER, A.A. & FRANKEL, A.E. (1989). Immunotoxins: a clinical review of their use in the treatment of malignancies. J. Clin. Oncol., 7, 1932
-
(1989)
J. Clin. Oncol.
, vol.7
, pp. 1932
-
-
Hertler, A.A.1
Frankel, A.E.2
-
26
-
-
0024556901
-
An anti-CD5 immunotoxin for chronic lymphyocytic leukemia: Enhancement of cytotoxicity with human serum albumin- monensin
-
HERTLER, A.A., SCHLOSSMAN, DM., BOROWITZ, M.J., BLYTH-MAN, H.E., CASELLAS, P. & FRANKEL, A.E. (1989a). An anti-CD5 immunotoxin for chronic lymphyocytic leukemia: enhancement of cytotoxicity with human serum albumin- monensin. Int. J. Cancer, 43, 215
-
(1989)
Int. J. Cancer
, vol.43
, pp. 215
-
-
Hertler, A.A.1
Schlossman, D.M.2
Borowitz, M.J.3
Blyth-Man, H.E.4
Casellas, P.5
Frankel, A.E.6
-
27
-
-
0024454978
-
An immunotoxin for the treatment of T-acute lymphoblastic leukemic meningitis: Studies in rhesus monkeys. Cancer Immunol
-
HERTLER, A.A., SCHLOSSMAN, D M., BOROWITZ, M.J., POPLACK, D.G. & FRANKEL, A.E. (1989b). An immunotoxin for the treatment of T-acute lymphoblastic leukemic meningitis: studies in rhesus monkeys. Cancer Immunol. Immunother., 28, 59
-
(1989)
Immunother.
, vol.28
, pp. 59
-
-
Hertler, A.A.1
Schlossman, D.M.2
Borowitz, M.J.3
Poplack, D.G.4
Frankel, A.E.5
-
28
-
-
0025924795
-
Preclinical assessments of 90Y-labelled Cl 10 anti- carcinoembryonic antigen immunotoxin: A therapeutic immuno- conjugate for human colon cancer
-
90Y-labelled Cl 10 anti- carcinoembryonic antigen immunotoxin: a therapeutic immuno- conjugate for human colon cancer. Cancer Res., 51, 255
-
(1991)
Cancer Res.
, vol.51
, pp. 255
-
-
Ito, T.1
Qiu, H.2
Collins, J.A.3
Brill, B.4
Johnson, D.K.5
Griffin, T.W.6
-
29
-
-
0025852415
-
Suppression of the immune response to immunotoxins with anti-CD4 monoclonal antibodies
-
JIN, F.-S., YOULE, R.J., JOHNSON, V.G. & 4 others (1991). Suppression of the immune response to immunotoxins with anti-CD4 monoclonal antibodies. J. Immunol., 146, 1806
-
(1991)
J. Immunol.
, vol.146
, pp. 1806
-
-
Jin, F.-S.1
Youle, R.J.2
Johnson, V.G.3
-
30
-
-
0023838032
-
The role of the diphtheria toxin receptor in cytosol translocation
-
JOHNSON, V.G., WILSON, D., GREENFIELD, L. & YOULE, R.J. (1988). The role of the diphtheria toxin receptor in cytosol translocation. J. Biol. Chem., 263, 1295
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 1295
-
-
Johnson, V.G.1
Wilson, D.2
Greenfield, L.3
Youle, R.J.4
-
31
-
-
0024552545
-
Improved tumor-specific immunotoxins in the treatment of CNS and leptomeningeal neoplasia
-
JOHNSON, V.G., WROBEL, C., WILSON, D. & 4 others (1989). Improved tumor-specific immunotoxins in the treatment of CNS and leptomeningeal neoplasia. J. Neurosurg., 70, 240
-
(1989)
J. Neurosurg.
, vol.70
, pp. 240
-
-
Johnson, V.G.1
Wrobel, C.2
Wilson, D.3
-
32
-
-
0025882239
-
The galactose-binding sites of the cytotoxic lectin ricin can be chemically blocked in high yield with reactive ligands prepared by chemical modification of glycopeptides containing triantennary N-linked oligosaccharides
-
LAMBERT, J.M., MCINTYRE, G., GAUTHIER, M.N. & 5 Others (1991). The galactose-binding sites of the cytotoxic lectin ricin can be chemically blocked in high yield with reactive ligands prepared by chemical modification of glycopeptides containing triantennary N-linked oligosaccharides. Biochemistry, 30, 3234
-
(1991)
Biochemistry
, vol.30
, pp. 3234
-
-
Lambert, J.M.1
McIntyre, G.2
Gauthier, M.N.3
-
33
-
-
0037723598
-
Pharmacokinetics and immune response to Xomazyme-Mel in melanoma patients. Antibody Immunoconj
-
LOBUGLIO, A.F., KHAZAELI, M.B., LEE, J. & 4 others (1988). Pharmacokinetics and immune response to Xomazyme-Mel in melanoma patients. Antibody Immunoconj. Radiopharm., 1, 305
-
(1988)
Radiopharm.
, vol.1
, pp. 305
-
-
Lobuglio, A.F.1
Khazaeli, M.B.2
Lee, J.3
-
34
-
-
0024240580
-
Cytotoxic effects of anti-CD5 radioimmunotoxins on human tumors in vitro and in a nude mouse model
-
MANSKE, J.M., BUCHSBAUM, D.J., HANNA, D.E. & VALLERA, D A. (1988). Cytotoxic effects of anti-CD5 radioimmunotoxins on human tumors in vitro and in a nude mouse model. Cancer Res., 48, 7107
-
(1988)
Cancer Res.
, vol.48
, pp. 7107
-
-
Manske, J.M.1
Buchsbaum, D.J.2
Hanna, D.E.3
Vallera, D.A.4
-
35
-
-
0025253402
-
Evaluation of ricin A chain-containing immunotoxins directed against different epitopes on the δ-chain of cell surface-associated IgD on murine B cells
-
MAY, R.D., FINKELMAN, F.D., WHEELER, H.T., UHR, J.W. & VITETTA, E.S. (1990). Evaluation of ricin A chain-containing immunotoxins directed against different epitopes on the δ-chain of cell surface-associated IgD on murine B cells. J. Immunol., 144, 3637
-
(1990)
J. Immunol.
, vol.144
, pp. 3637
-
-
May, R.D.1
Finkelman, F.D.2
Wheeler, H.T.3
Uhr, J.W.4
Vitetta, E.S.5
-
36
-
-
0025441143
-
Human antibody responses to components of the monoclonal antimelanoma antibody ricin A chain immunotoxin XomaZyme MEL
-
MISCHAK, R.P., FOXALL, C., ROSENDORF, L.L., KNEBEL, K., SCAN-NON, P.J. & SPITLER, L.E. (1990). Human antibody responses to components of the monoclonal antimelanoma antibody ricin A chain immunotoxin XomaZyme MEL. Mol. Biother., 2, 104
-
(1990)
Mol. Biother.
, vol.2
, pp. 104
-
-
Mischak, R.P.1
Foxall, C.2
Rosendorf, L.L.3
Knebel, K.4
Scan-Non, P.J.5
Spitler, L.E.6
-
37
-
-
0025243542
-
Processing of Pseudomonas exotoxin by a cellular protease results in the generation of a 37, 000 Da toxin fragment that is translocated to the cytosol
-
OGATA, M., CHAUDHARY, V.K., PASTAN, I. & FITZGERALD, D.J. (1990). Processing of Pseudomonas exotoxin by a cellular protease results in the generation of a 37, 000 Da toxin fragment that is translocated to the cytosol. J. Biol. Chem., 265, 20678
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 20678
-
-
Ogata, M.1
Chaudhary, V.K.2
Pastan, I.3
Fitzgerald, D.J.4
-
38
-
-
0025119680
-
Cytotoxicity of a recombinant ricin A chain fusion protein containing a proteolytically-cleavable spacer sequence
-
O’hare, M., Brown, A.N., Hussain, K. & 6 others (1990). Cytotoxicity of a recombinant ricin A chain fusion protein containing a proteolytically-cleavable spacer sequence. FEBS Lett., 273, 200
-
(1990)
FEBS Lett.
, vol.273
, pp. 200
-
-
O’hare, M.1
Brown, A.N.2
Hussain, K.3
-
39
-
-
0025180502
-
Antimelanoma monoclonal antibody-ricin A chain immunocon- jugate (XMMME-001-RTA) plus cyclophosphamide in the treatment of metastatic malignant melanoma: Results of a phase II trial
-
ORATZ, R., SPEYER, J.L., WERNZ, J.C. & 4 others (1990). Antimelanoma monoclonal antibody-ricin A chain immunocon- jugate (XMMME-001-RTA) plus cyclophosphamide in the treatment of metastatic malignant melanoma: results of a phase II trial. J. Biol. Resp. Modif., 9, 345
-
(1990)
J. Biol. Resp. Modif.
, vol.9
, pp. 345
-
-
Oratz, R.1
Speyer, J.L.2
Wernz, J.C.3
-
40
-
-
0023919605
-
Immunoconjugate generation between the ribosome-inactivating protein restrictocin and an anti-human breast carcinoma MAB. Cancer Immunol
-
ORLANDI, R., CANEVARI, S., CONDE, F.P. & 4 others (1988). Immunoconjugate generation between the ribosome-inactivating protein restrictocin and an anti-human breast carcinoma MAB. Cancer Immunol. Immunother., 26, 114
-
(1988)
Immunother.
, vol.26
, pp. 114
-
-
Orlandi, R.1
Canevari, S.2
Conde, F.P.3
-
41
-
-
0024355411
-
Chemo- immunotoxin therapy against a human colon tumor (HT-29) xenografted into nude mice
-
PEARSON, J.W., FITZGERALD, D.J.P., WILLINGHAM, M.C., WIL-TROUT, R.H., PASTAN, I. & LONGO, D.L. (1989a). Chemo- immunotoxin therapy against a human colon tumor (HT-29) xenografted into nude mice. Cancer Res., 49, 3562
-
(1989)
Cancer Res.
, vol.49
, pp. 3562
-
-
Pearson, J.W.1
Fitzgerald, D.J.P.2
Willingham, M.C.3
Wil-Trout, R.H.4
Pastan, I.5
Longo, D.L.6
-
42
-
-
0025082853
-
Enhanced therapeutic efficacy against ovarian tumor xenograft of immunotoxins used in conjunction with recombinant a-interferon
-
PEARSON, J.W., HEDRICH, E., FOGLER, W.E. & 8 others (1990). Enhanced therapeutic efficacy against ovarian tumor xenograft of immunotoxins used in conjunction with recombinant a-interferon. Cancer Res., 50, 6379
-
(1990)
Cancer Res.
, vol.50
, pp. 6379
-
-
Pearson, J.W.1
Hedrich, E.2
Fogler, W.E.3
-
43
-
-
0024420679
-
Enhanced therapeutic efficacy of an immunotoxin in combination with chemotherapy against an intraperitoneal tumour xenograft in athymic mice
-
PEARSON, J.W., SIVAM, G., MANGER, R., WILTROUT, R.H., MORGAN, A.C. Jr & LONGO, D.L. (1989b). Enhanced therapeutic efficacy of an immunotoxin in combination with chemotherapy against an intraperitoneal tumour xenograft in athymic mice. Cancer Res., 49, 4990
-
(1989)
Cancer Res.
, vol.49
, pp. 4990
-
-
Pearson, J.W.1
Sivam, G.2
Manger, R.3
Wiltrout, R.H.4
Morgan, A.C.5
Longo, D.L.6
-
44
-
-
0024227006
-
Ricin A chain-containing immunotoxins directed against different epitopes on the CD2 molecule differ in their ability to kill normal and malignant T cells
-
PRESS, O.W., MARTIN, P.J., THORPE, P.E. & VITETTA, E.S. (1988). Ricin A chain-containing immunotoxins directed against different epitopes on the CD2 molecule differ in their ability to kill normal and malignant T cells. J. Immunol., 141, 4410
-
(1988)
J. Immunol.
, vol.141
, pp. 4410
-
-
Press, O.W.1
Martin, P.J.2
Thorpe, P.E.3
Vitetta, E.S.4
-
45
-
-
0024545945
-
Cure of experimental human malignant mesothelioma in athymic mice by diphtheria toxin
-
RASO, V. & MCGRATH, J. (1989). Cure of experimental human malignant mesothelioma in athymic mice by diphtheria toxin. J. Natl Cancer Inst., 81, 623
-
(1989)
J. Natl Cancer Inst.
, vol.81
, pp. 623
-
-
Raso, V.1
McGrath, J.2
-
46
-
-
0025365573
-
Parameters affecting tumor-specific delivery of anti-CD5 antibody-ricin A chain immunotoxins in vivo
-
Rostaing-Capaillon, O. & Casellas, P. (1990). Parameters affecting tumor-specific delivery of anti-CD5 antibody-ricin A chain immunotoxins in vivo. Cancer Res., 50, 2909
-
(1990)
Cancer Res.
, vol.50
, pp. 2909
-
-
Rostaing-Capaillon, O.1
Casellas, P.2
-
47
-
-
45249130552
-
Therapy of metastatic malignant melanoma using Xomazyme-Mel, a murine monoclonal anti-melanoma ricin A chain immunotoxin
-
SPITLER, L.E., MISCHAK, R. & SCANNON, P. (1989). Therapy of metastatic malignant melanoma using Xomazyme-Mel, a murine monoclonal anti-melanoma ricin A chain immunotoxin. Nucl. Med. Biol., 16, 625
-
(1989)
Nucl. Med. Biol.
, vol.16
, pp. 625
-
-
Spitler, L.E.1
Mischak, R.2
Scannon, P.3
-
48
-
-
0025484221
-
The effects of cyclophosphamide on the toxicity and immunogenicity of ricin A chain immunotoxin in rats
-
STOUDEMIRE, J.B., MISCHAK, R., FOXALL, C., HARKONEN, W.S., DEL RIO, M. & SPITLER, L.E. (1990). The effects of cyclophosphamide on the toxicity and immunogenicity of ricin A chain immunotoxin in rats. Mol. Biother., 2, 179
-
(1990)
Mol. Biother.
, vol.2
, pp. 179
-
-
Stoudemire, J.B.1
Mischak, R.2
Foxall, C.3
Harkonen, W.S.4
Del Rio, M.5
Spitler, L.E.6
-
49
-
-
0025200957
-
Pharmacokinetic analysis of immunotoxin uptake in solid tumors: Role of plasma kinetics, capillary permeability and binding
-
SUNG, C., YOULE, R.J. & DEDRICK, R.L. (1990). Pharmacokinetic analysis of immunotoxin uptake in solid tumors: role of plasma kinetics, capillary permeability and binding. Cancer Res., 50, 7382
-
(1990)
Cancer Res.
, vol.50
, pp. 7382
-
-
Sung, C.1
Youle, R.J.2
Dedrick, R.L.3
-
50
-
-
0023689869
-
Improved antitumor effects of immunotoxins prepared with deglycosylated ricin A chain and hindered disulphide linkages
-
THORPE, P.E., WALLACE, P.M., KNOWLES, P.P. & 5 others (1988). Improved antitumor effects of immunotoxins prepared with deglycosylated ricin A chain and hindered disulphide linkages. Cancer Res., 48, 6396
-
(1988)
Cancer Res.
, vol.48
, pp. 6396
-
-
Thorpe, P.E.1
Wallace, P.M.2
Knowles, P.P.3
-
51
-
-
0023832767
-
An assay that predicts the ability of monoclonal antibodies to form potent ricin A chain-containing immunotoxins
-
TILL, M., MAY, R.D., UHR, J.W., THORPE, P.E. & VITETTA, E.S. (1988). An assay that predicts the ability of monoclonal antibodies to form potent ricin A chain-containing immunotoxins. Cancer Res., 48, 1119
-
(1988)
Cancer Res.
, vol.48
, pp. 1119
-
-
Till, M.1
May, R.D.2
Uhr, J.W.3
Thorpe, P.E.4
Vitetta, E.S.5
-
52
-
-
0023485290
-
Redesigning nature’s poisons to create anti-tumor agents
-
VITETTA, E.S., FULTON, R.J., MAY, R.D., TILL, M. & UHR, J.W. (1987). Redesigning nature’s poisons to create anti-tumor agents. Science, 238, 1098
-
(1987)
Science
, vol.238
, pp. 1098
-
-
Vitetta, E.S.1
Fulton, R.J.2
May, R.D.3
Till, M.4
Uhr, J.W.5
-
53
-
-
0025341724
-
Expression and functional properties of genetically engineered ricin B chain lacking galactosebinding ability
-
VITETTA, E.S. & YEN, N. (1990). Expression and functional properties of genetically engineered ricin B chain lacking galactosebinding ability. Biochim. Biophys. Acta, 1049, 151
-
(1990)
Biochim. Biophys. Acta
, vol.1049
, pp. 151
-
-
Vitetta, E.S.1
Yen, N.2
-
54
-
-
0023689010
-
Immunotherapy in patients with advanced malignant melanoma using a monoclonal anti-melanoma antibody ricin A chain immunotoxin
-
VON WUSSOW, P., SPITLER, L., BLOCH, B. & DEICHER, H. (1988). Immunotherapy in patients with advanced malignant melanoma using a monoclonal anti-melanoma antibody ricin A chain immunotoxin. Eur. J. Cancer Clin. Oncol., 24, Suppl. 2, S69
-
(1988)
Eur. J. Cancer Clin. Oncol., 24, Suppl
, vol.2
, pp. 569
-
-
Von Wussow, P.1
Spitler, L.2
Bloch, B.3
Deicher, H.4
-
55
-
-
0026057053
-
Comparative biochemical, cytotoxic and pharmacokinetic properties of immunotoxins made with native ricin A chain, ricin A, chain and recombinant ricin A chain
-
WAWRZYNCZAK, E.J., CUMBER, A.J., HENRY, R.V. & PARNELL, G.D. (1991a). Comparative biochemical, cytotoxic and pharmacokinetic properties of immunotoxins made with native ricin A chain, ricin A, chain and recombinant ricin A chain. Int. J. Cancer, 47, 130
-
(1991)
Int. J. Cancer
, vol.47
, pp. 130
-
-
Wawrzynczak, E.J.1
Cumber, A.J.2
Henry, R.V.3
Parnell, G.D.4
-
56
-
-
84966144656
-
Pharmacokinetics of recombinant monoclonal antibodies with different biological properties
-
WAWRZYNCZAK, E.J., CUMBER, A.J., PARNELL, G.D., DENHAM, S., JONES, P.T. & WINTER, G. (1991b). Pharmacokinetics of recombinant monoclonal antibodies with different biological properties. Br. J. Cancer, 63 (Suppl_XIII), 72
-
(1991)
Br. J. Cancer
, vol.63
, pp. 72
-
-
Wawrzynczak, E.J.1
Cumber, A.J.2
Parnell, G.D.3
Denham, S.4
Jones, P.T.5
Winter, G.6
-
57
-
-
0025685603
-
Pharmacokinetics in the rat of a panel of immunotoxins made with abrin A chain, ricin A chain, gelonin and momordin
-
WAWRZYNCZAK, E.J., CUMBER, A.J., HENRY, R.V. & 5 others (1990). Pharmacokinetics in the rat of a panel of immunotoxins made with abrin A chain, ricin A chain, gelonin and momordin. Cancer Res., 50, 7519
-
(1990)
Cancer Res.
, vol.50
, pp. 7519
-
-
Wawrzynczak, E.J.1
Cumber, A.J.2
Henry, R.V.3
-
59
-
-
0023694143
-
Ricin B chain-containing immunotoxins prepared with heat-denatured B chain lacking galactose-binding ability potentiate the cytotoxicity of a cell-reactive ricin A chain immunotoxin
-
WAWRZYNCZAK, E.J., DRAKE, A.F., WATSON, G.J., THORPE, P.E. & VITETTA, E.S. (1988). Ricin B chain-containing immunotoxins prepared with heat-denatured B chain lacking galactose-binding ability potentiate the cytotoxicity of a cell-reactive ricin A chain immunotoxin. Biochim. Biophys. Acta, 971, 55
-
(1988)
Biochim. Biophys. Acta
, vol.971
, pp. 55
-
-
Wawrzynczak, E.J.1
Drake, A.F.2
Watson, G.J.3
Thorpe, P.E.4
Vitetta, E.S.5
-
60
-
-
0026035077
-
Biochemical, cytotoxic and pharmacokinetic properties of an immunotoxin composed of a mouse monoclonal antibody Fib75 and the ribosome-inactivating protein α-sarcin from Aspergillus giganteus
-
WAWRZYNCZAK, E.J., HENRY, R.V., CUMBER, A.J., PARNELL, G.D., DERBYSHIRE, E.J. & ULBRICH, N. (1991c). Biochemical, cytotoxic and pharmacokinetic properties of an immunotoxin composed of a mouse monoclonal antibody Fib75 and the ribosome-inactivating protein α-sarcin from Aspergillus giganteus. Eur. J. Biochem., 196, 203
-
(1991)
Eur. J. Biochem.
, vol.196
, pp. 203
-
-
Wawrzynczak, E.J.1
Henry, R.V.2
Cumber, A.J.3
Parnell, G.D.4
Derbyshire, E.J.5
Ulbrich, N.6
-
61
-
-
0025970022
-
Blocked and non-blocked ricin immunotoxins against the CD4 antigen exhibit higher cytotoxic potency than a ricin A chain immunotoxin potentiated with ricin B chain or with a ricin B chain immunotoxin. Cancer Immunol
-
WAWRZYNCZAK, E.J., WATSON, G.J., CUMBER, A.J. & 4 others (1991d). Blocked and non-blocked ricin immunotoxins against the CD4 antigen exhibit higher cytotoxic potency than a ricin A chain immunotoxin potentiated with ricin B chain or with a ricin B chain immunotoxin. Cancer Immunol. Immunother., 32, 289
-
(1991)
Immunother.
, vol.32
, pp. 289
-
-
Wawrzynczak, E.J.1
Watson, G.J.2
Cumber, A.J.3
-
62
-
-
0024383404
-
Phase I evaluation of an anti-breast carcinoma monoclonal antibody 260F9-recombinant ricin A chain immunoconjugate
-
WEINER, L.M., O’dwyer, J., Kitson, J. & 5 others (1989). Phase I evaluation of an anti-breast carcinoma monoclonal antibody 260F9-recombinant ricin A chain immunoconjugate. Cancer Res., 49, 4062
-
(1989)
Cancer Res.
, vol.49
, pp. 4062
-
-
Weiner, L.M.1
O’dwyer, J.2
Kitson, J.3
-
63
-
-
0025331660
-
Diphtheria toxin effects on brain-tumor xenografts: Implications for protein-based brain-tumor chemotherapy
-
WROBEL, C.J., WRIGHT, DC., DEDRICK, R.L. & YOULE, R.J. (1990). Diphtheria toxin effects on brain-tumor xenografts: implications for protein-based brain-tumor chemotherapy. J. Neurosurg., 72, 946
-
(1990)
J. Neurosurg.
, vol.72
, pp. 946
-
-
Wrobel, C.J.1
Wright, D.C.2
Dedrick, R.L.3
Youle, R.J.4
-
64
-
-
0025128963
-
Synergistic potentiation of in vivo antitumor activity of anti-human T- leukemia immunotoxins by recombinant a-interferon and daunorubicin
-
YOKOTA, S., HARA, H., LUO, Y. & SEON, B.K. (1990). Synergistic potentiation of in vivo antitumor activity of anti-human T- leukemia immunotoxins by recombinant a-interferon and daunorubicin. Cancer Res., 50, 32
-
(1990)
Cancer Res.
, vol.50
, pp. 32
-
-
Yokota, S.1
Hara, H.2
Luo, Y.3
Seon, B.K.4
|