Modulation of immune function by intestinal neuropeptides

Acta Oncologica

Volumn 30, Issue 4, 1991, Pages 509-517

  Sirinek, L P ^a   O'dorisio, M S ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

Immunomodulators; Neuroimmune axis; Neuropeptides

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CHOLECYSTOKININ; GASTROINTESTINAL HORMONE; LEUCINE ENKEPHALIN; METENKEPHALIN; NEUROPEPTIDE Y; SUBSTANCE P; VASOACTIVE INTESTINAL POLYPEPTIDE;

ANIMAL EXPERIMENT; CONFERENCE PAPER; CONTROLLED STUDY; HUMAN; IMMUNOMODULATION; PRIORITY JOURNAL;

CALCITONIN GENE-RELATED PEPTIDE; CHOLECYSTOKININ; ENDORPHINS; GASTROINTESTINAL SYSTEM; IMMUNE SYSTEM; LYMPHOCYTES; NEUROPEPTIDE Y; SOMATOSTATIN; SUBSTANCE P; VASOACTIVE INTESTINAL PEPTIDE;

EID: 0025827365     PISSN: 0284186X     EISSN: None     Source Type: Journal    
DOI: 10.3109/02841869109092410     Document Type: Article

References (96)

1. Immunomodulation by tachykinin neuropeptides
2. Hormones of the gastrointestinal tract
3. Ultrastructural localisation of substance P, vasoactive intestinal polypeptide, somatostatin and neuropeptide Y immunoreactivity in perivascular nerve plexuses of the gut
4. Substance P and substance K receptor binding sites in the human gastrointestinal tract: localization by autoradiography
5. Neuropeptide innervation of lymphoid organs
6. Binding charcteristics and affinity labeling of protein constituents of the human IM-9 lumphoblast receptor for substance P
7. Substance P recognition by subset of human T lymphocytes
8. Immunoaffinity purification of membrane protein constituents of the IM-9 lymphoblast receptor for substance P
9. Stereospecific receptors for substance P on cultured human IM-9 lymphoblasts
10. Processing of the human IM-9 lymphoblast substance P receptor. Biosynthetic and degradation studies using a monoclonal antibody
11. Molecular characterization of a functional cDNA for rat substance P receptor
12. Molecular characterization of a functional cDNA encoding the rat substance P receptor
13. The differential effect with time of neuropeptides on the proliferative responses of murine Peyer’s patch and splenic lymphocytes
14. Specific stimulation of human T lymphocytes by substance P
15. Differential effects of vasoactive intestinal peptide, substance P, and somatostatin on immunoglobulin synthesis and proliferations by lymphocytes from Peyer’s patches, mesenteric lymph nodes, and spleen
16. Substance P enhances interferon-gamma production by human blood mononuclear cells
17. In vivo immunomodulation by the neuropeptide substance P
18. Activation of macrophages by substance P: induction of oxidative burst and thromboxane release
19. Substance P: binding properties and studies on cellular responses in guinea pig macrophages
20. Neuropeptides modulating macrophage function
21. The neuropeptide substance P stimulates production of inter-leukin 1 in human blood monocytes: activated cells are preferentially influenced by the neuropeptide
22. Effect of neuropeptides on production of inflammatory cytokines by human monocytes
23. Substance P receptor-mediated chemotaxis of human monocytes
24. Activation of human neutrophils by substance P. Effect on oxidative metabolism, exocytosis, cytosolic Ca2 ’ concentration and inositol phosphate formation
25. Substance P activates and modulates neutrophil oxidative metabolism and aggregation
26. Sensory neuropeptides (substance P) and 4–11 SP enhance human neutrophils chemiluminescence; the role of L-arginine
27. Comparsion of the histamine-releasing action of substance P on mast cells and basophils from different species and tissues
28. Pathophysiological significance of the distribution of histamine receptor sub-types: a proposed dual role for histamine in inflammation and type I hypersensitivity reactions
29. Enhancement of phagocytosis—a newly found activity of substance P residing in its n-terminal tetrapeptide sequence
30. Somatostatin
31. Distribution of somatostatin receptors on murine spleen and Peyer’s patch T and B lymphocytes
32. Identification of human mononuclear leukocytes bearing receptors for somatostatin and glucagon
33. Distinct subsets of somatostatin receptors on cultured human lymphocytes
34. Gastrointestinal regulatory peptides modulate in vitro immune reactions of mouse lymphoid cells
35. Immunomodulatory action of somatostatin
36. Effect of somatostatin on the proliferation of mouse spleen lymphocytes in vitro
37. Effect of the neuropeptides beta-MSH, neurotensin, NPY, PHI, somatostatin and substance P on proliferation of lymphocytes in vitro
38. Inhibition by somatostatin of the proliferation of T-lymphocytes and Molt-4 lymphoblasts
39. Short-term somatostatin infusion affects T lymphocyte responsiveness in humans
40. Suppressed colony formation of peripheral blood lymphocytes in a patient with somatostatinoma
41. The mechanism of anit-body-dependent cellular cytotoxicity stimulation by somatostatin in rat peritoneal macrophages
42. Modulation of hepatic reticuloendothelial system phagocytosis by pancreatic hormones
43. Inhibition by somatostatin of the release of mediators from human basophils and rat leukemic basophils
44. Neuropeptide regulation of the expression of immediate hypersensitivity
45. Endogenous somatostatin-like peptides of rat basophilic leukemia cells
46. Vasoactive intestinal pep-tide-containing nerves in Peyer’s patches
47. Demonstration of a functional receptor for vasoactive intestinal polypeptide on Molt 4b T lymphoblasts
48. Specific binding sites for vasoactive intestinal polypeptide on nonadherent peripheral blood lymphocytes
49. Interaction of vasoactive intestinal peptide with mouse lymphocytes: specific binding and the modulation of mitogen responses
50. Identification of high affinity receptors for vasoactive intestinal peptide on human lymphocytes of B cell lineage
51. Selective effects of vasoactive intestinal peptide on the mitogenic response of murine T cells
52. In vitro alteration of receptors for vasoactive intestinal peptide changes the in vivo localization of mouse T cells
53. Modification of lymphocyte traffic by vasoactive neurotransmitter substances
54. Depression of lymphocyte traffic in sheep by vasoactive intestinal peptide (VIP)
55. The effects of vasoactive intestinal peptide on human natural killer cell function
56. Vasoactive intestinal polypeptide modulation of lymphocyte adenylate cyclase
57. Interaction of vasoactive intestinal peptide (VIP) with human peripheral blood lymphocytes: specific binding and cyclic AMP production
58. Cyclic AMP-dependent protein kinase in Molt 4b lymphoblasts: identification by photoaffinity labeling and activation in intact cells by vasoactive intestinal polypeptide (VIP) and peptide histidine isoleucine (PHI)
59. Binding of vasoactive intestinal polypeptide (VIP) by human blood monocytes: demonstration of specific binding sites
60. Effect of VIP on the respiratory burst in human monocytes ex vivo during prolonged strain and energy deficiency
61. Vasoactive intestinal peptide inhibits the respiratory burst in human monocytes by a cyclic AMP-mediated mechanism
62. Biochemistry and the central nervous system
63. Noradrenergic and peptidergic innervation of lymphoid tissue
64. Immunologic patterns of methionine-enkephalin, and therapeutic implications in AIDS, ARC, and cancer
65. Opiate receptors on lymphocytes and platelets in man
66. Methionine-enkephalin stimulates in vitro proliferation of human peripheral lymphocytes via delta-opioid receptors
67. The effect of the stimulation of opioid receptors on lymphocyte functional activity in vivo
68. Methionine-enkephalin alteration of mito-genic and mixed lymphocyte culture responses in zinc-deficient mice
69. Enkephalins as immunomodula-tors
70. Importance of opiate receptor ligands in regulating lymphocyte proliferative activity
71. Neuroimmunomodulation with enkephalins: in vitro enhancement of natural killer cell activity in peripheral blood lymphocytes from cancer patients
72. Modulation of lymphocyte motility by beta-endorphin and met-enkephalin
73. Enkephalins: immunomodulators
74. Evidence for an inhibitory role of beta-endorphin and other opioids on human total T rosette formation
75. Enkephalins and immunity I: in vivo suppression and potentiation of humoral immune response
76. Enkephalins and immunity. II: in vivo modulation of cell-mediated immunity
77. Bidirectional effect of met-enkephalin on macrophage effector functions
78. Combinative ligand-receptor interactions: epinephrine depresses RAW264 macrophage antibody-dependent phagocytosis in the absence and presence of met-enkephalin
79. Metenkephalin induced alterations of macrophage functions
80. Enhancement of interleukin-1 production in mouse peritoneal macrophages by methionine-enkephalin
81. Enhanced oxygen metabolism of peritoneal macrophages in the presence of murine neuroblastoma cells is partly caused by enkephalins
82. Effect of neuropeptides on macrophage mediated cytotoxicity in normal donors and cancer patients
83. Opioid peptides modulate the organization of vimentin filaments, phagocytic activity, and expression of surface molecules in monocytes
84. The effect of enkephalins and prostaglandins on O-2 release by neutrophils
85. Modulation of human neutrophil adherence by beta-endorphin and met-enkephalin
86. Calciton In: physiology, biosynthesis, secretion, metabolism, and mode of action
87. Intestinal mucosal mast cells in normal and nematode-infected rat intestines are in intimate contact with peptidergic nerves
88. Characterization of the calcitonin gene-related peptide receptor in mouse T lymphocytes
89. Inhibition of mitogen-stimulated T lymphocyte proliferation by calcitonin gene-related peptide
90. Peptides encoded by the calcitonin gene inhibit macrophage function
91. Identification of high affinity calcitonin gene-related peptide receptors on a murine macrophage-like cell line
92. Eosinophil chemotactic response to rat CGRP-1 is increased after exposure to trypsin or guinea-pig lung particulate fraction
93. Neuropeptide regulation of human thymocyte, guinea pig T lymphocyte and rat B lymphocyte mitogenesis
94. Neuropeptide Y modulates t cell proliferation in vitro: A new interaction of the immune and neuroendocrine systems
95. The neuroendocrine-immune network in the gastrointestinal tract
96. Cholecystokinin mediates a calcium signal in human peripheral blood mononuclear cells and is a co-mitogen