SCOPUS 정보 검색 플랫폼

Volumn 2, Issue 4, 1991, Pages 235-238

Stereocontrolled synthesis of 4,4,4-trifluorothreonine

Author keywords

[No Author keywords available]

Indexed keywords

4,4,4 TRIFLUOROTHREONINE; ANTINEOPLASTIC AGENT; FLUOROURACIL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHEMICAL STRUCTURE; CYTOTOXICITY; DRUG SYNTHESIS; LEUKEMIA L 1210; MOUSE; NONHUMAN; TUMOR CELL;

EID: 0025822430 PISSN: 09574166 EISSN: 1362511X Source Type: Journal
DOI: 10.1016/S0957-4166(00)80041-5 Document Type: Article

Times cited : (38)

References (11)

1
- 0003828324
- G.C. Barrett, Chapman and Hall Ltd, London
- (1985) Chemistry and Biochemistry of Amino Acids
- Hunt¹

2
- 0001055167
- Stereospecific synthesis of racemic daunosamine. Diastereofacial selectivity in a nitrone cycloaddition
- (1983) Journal of the American Chemical Society , vol.105 , pp. 1986
- Deshong¹ Leginus²

3
- 0020558592
- (1983) Tetrahedron Lett. , vol.24 , pp. 4637
- Heathcock¹ Montgomery²

4
- 0001763618
- Carbamate-mediated functionalization of unsaturated alcohols. 3. Intramolecular Michael addition of O-carbamates to .alpha.,.beta.-unsaturated esters. A new diastereoselective amination in an acyclic system
- (1985) Journal of the American Chemical Society , vol.107 , pp. 1797
- Hiyama¹ Sugimoto² Yamazaki³ Ito⁴

7
- 0000189243
- (1988) Tetrahedron , vol.44 , pp. 5553
- Guanti¹ Banfi² Narisano³

9
- 84912871199
- Asymmetric hydrolysis: A suspension of lipase MY (Meito Sangyo Co. Ltd., 6.0 g), and syn-(3) (5.7 g) in a buffer solution (pH 7.3, 120 ml) was stirred at 40–41°C. After 96h of stirring, the mixture was acidified with 1N HCl and oily materials was extracted with ethyl acetate. After determining the hydrolysis conversion (37%) by 19F NMR signal intensities, the products were separated by column chromatography on silica gel, producing syn-2R,3R-(4a) (86% ee, 1.6 g) and syn (3)(3.2 g). Further, syn-2R,3R-(4a)(86% ee) was converted to the acetate by AcC and then enzymatic resolution with lipase MY was carried out. After determining the hydrolysis conversion (41%), the mixture was worked up similarly, giving syn-2R,3R-(4a)(97% ee).

10
- 0343221213
- (1987) J. Org. Chem. , vol.52 , pp. 3211
- Lin¹ Yamazaki² Kitazume³

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.