Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

Biochemical and Biophysical Research Communications

Volumn 175, Issue 3, 1991, Pages 880-885

  Artursson, P ^a   Karlsson, J ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALPRENOLOL; ARGIPRESSIN; ATENOLOL; CORTICOSTERONE; DESMOPRESSIN; DEXAMETHASONE; FELODIPINE; HYDROCORTISONE; MACROGOL; MANNITOL; METOPROLOL; OLSALAZINE; PRACTOLOL; PROPRANOLOL; SALAZOSULFAPYRIDINE; SALICYLIC ACID; TERBUTALINE; TESTOSTERONE; WARFARIN;

ARTICLE; DRUG ABSORPTION; HUMAN; HUMAN CELL; INTESTINE ABSORPTION; INTESTINE EPITHELIUM CELL; MEMBRANE PERMEABILITY; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL;

ADENOCARCINOMA; ADMINISTRATION, ORAL; ADRENERGIC BETA-ANTAGONISTS; CARBON RADIOISOTOPES; CELL LINE; CELL MEMBRANE PERMEABILITY; COLONIC NEOPLASMS; EPITHELIUM; HUMAN; INTESTINAL ABSORPTION; MODELS, BIOLOGICAL; PHARMACEUTICAL PREPARATIONS; SUPPORT, NON-U.S. GOV'T; TRITIUM;

EID: 0025804183     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/0006-291X(91)91647-U     Document Type: Article

References (37)

1. Pharmacokinetics of acetylsalicylic acid and salicylic acid after intravenous administration in man
2. Pharmacokinetic evaluation in man of terbutaline given as separate enantiomers and as the racemate.
3. Physicochemical factors affecting β-adrenergic antagonist permeation across cultured hamster pouch buccal epithelium
4. A practitioner's perspective of the role of quantitative structure-activity analysis in medicinal chemistry