Mutant α subunits of Gi2 inhibit cyclic AMP accumulation

Nature

Volumn 351, Issue 6321, 1991, Pages 63-65

  Wong, Yung H ^a   Federman, Alex ^a   Pace, Ann M ^a   Zachary, Ian ^d   Evans, Tony ^b   Pouysségur, Jacques ^c   Bourne, Henry R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b GENENTECH INC   (United States)

^c CNRS   (France)

^d IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

AMINO ACID SEQUENCE; ANIMAL; ANTIBODIES; ARGININE; CELL LINE; CYCLIC AMP; CYSTINE; FORSKOLIN; GLUTAMINE; GTP-BINDING PROTEINS; IMMUNOBLOTTING; KINETICS; LEUCINE; MACROMOLECULAR SYSTEMS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANSFECTION; VIRULENCE FACTORS, BORDETELLA;

EID: 0025804127     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/351063a0     Document Type: Article

References (30)

1. Freissmuth, M., Casey, P. J. & Gilman, A. G. FASEB J. 3, 2125-2131 (1989).
2. Birnbaumer, L. A. Rev. Pharmac. Tox. 30, 675-705 (1990).
3. Bourne, H. R., Sanders, D. A. & McCormick, F. Nature 348, 125-132 (1990).
4. Masters, S. B. et al. J. biol. Chem. 264, 15467-15474 (1989).
5. Landis, C. A. et al. Nature 340, 692-696 (1989).
6. Graziano, M. P. & Gilman, A. G. J. biol. Cbem. 264, 15475-15482 (1989).
7. Freissmuth, M. & Gilman, A. G. J. biol. Chem. 264, 21907-21914 (1989).
8. Lyons, J. et al. Science 249, 655-659 (1990).
9. Seamon, K. & Daly, J. W. J. biol. Chem. 257, 9799-9801 (1981).
10. Murayama, T. & Ui, M. J. biol. Chem. 262, 5522-5529 (1987).
11. van Corven, E. J., Groenink, A., Jalink, K., Eichholtz, T. & Moolenaar, W. H. Cell 59, 45-54 (1989).
12. Zachary, I., Masters, S. B. & Bourne, H. R. Biochem. biophys. Res. Commun. 168, 1184-1193 (1990).
13. McFarland, K. C. et al. Science 245, 494-499 (1989).
14. Guyer, C. A. et al. J. biol. Chem. 265, 17307-17317 (1990).
15. Price, S. R., Barber, A. & Moss, J. in ADP-ribosylating Toxins and G Proteins. Insights into Signal Transduction (eds Moss, J. & Vaughan, M.) 397-424 (Am. Soc, Microbiology, Washington, DC, 1990).
16. Katada, T., Oinuma, M. & Ui, M. J. biol. Chem. 261, 5215-5221 (1986).
17. Gilman, A. G. A. Rev. Biochem. 56, 615-649 (1987).
18. Katada, T., Northup, J. K., Bokoch, G. M., Ui, M. & Gilman, A. G. J. biol. Chem. 259, 3578-3585 (1984).
19. Hildebrandt, J. D., Codina, J. & Birnbaumer, L. J. biol. Chem. 259, 13178-13185 (1984).
20. Kobayashi, I. et al. Eur. J. Biochem. 191, 499-506 (1990).
21. Hildebrandt, J. D., Hanoune, J. & Birnbaumer, L. J. biol. Chem. 257, 14723-14725 (1982).
22. Hildebrandt, J. D. et al. Nature 302, 706-709 (1983).
23. Jakobs, K. H., Aktories, K. & Schultz, G. Nature 303, 177-178 (1983).
24. Jakobs, K. H. & Schultz, G. Proc. natn. Acad. Sci. U.S.A. 80, 3899-3902 (1983).
25. Katada, T., Bockoch, G. M., Smigel, M. D., Ui, M. & Gilman, A. G, J. biol. Chem. 259, 3586-3595 (1984).
26. Sullivan, K. A., et al. Proc. natn. Acad. Sci. U.S.A. 83, 6687-6691 (1986).
27. Sullivan, K. A., et al. Nature 330, 758-760 (1987).
28. Salomon, Y., Londos, C. & Rodbell, M. Analyt. Biochem. 58, 541-548 (1974).
29. Evans, T., Fawzi, A., Fraser, E. D., Brown, M. L. & Northup, J. K. J. biol. Chem. 262, 176-181 (1987).
30. Chang, F.-H. & Bourne, H. R. Endocrinology 121, 1711-1715 (1987).