Effects of 4-hydroxynonenal, a product of lipid peroxidation, on cell proliferation and ornithine decarboxylase activity

Free Radical Research

Volumn 14, Issue 2, 1991, Pages 81-89

  Barrera, Giuseppina ^a   Brossa, Olga ^a   Fazio, Vito Michele ^b   Farace, Maria Giulia ^c   Paradisi, Luciana ^a   Gravela, Enrico ^a   Dianzani, Mario Umberto ^a  

^a Dipto di Med ed Oncol Sperim   (Italy)

^b CNR   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

4 hydroxynonenal; DNA synthesis; Leukemic cells; Ornithine decarboxylase

Indexed keywords

4 HYDROXYNONENAL; DNA; ENZYME INHIBITOR; ORNITHINE DECARBOXYLASE;

ARTICLE; CELL GROWTH; HUMAN; HUMAN CELL; LEUKEMIA CELL; LIPID PEROXIDATION;

ALDEHYDES; CELL DIVISION; DNA, NEOPLASM; HUMAN; LIPID PEROXIDATION; ORNITHINE DECARBOXYLASE; SUPPORT, NON-U.S. GOV'T; TUMOR CELLS, CULTURED;

EID: 0025803588     PISSN: 10715762     EISSN: None     Source Type: Journal    
DOI: 10.3109/10715769109094120     Document Type: Article

References (26)

1. Lipid peroxidation products: Formation, chemical properties and biological activities
2. Metabolism of the lipid peroxidation product 4-hydroxynonenal by isolated hepatocytes and by liver cytosolic fraction
3. Effects of the lipid peroxidation product 4-hydroxynonenal and related aldehydes on proliferation and viability of cultured Ehrlich ascites tumor cells
4. Aliphatic aldehydes inhibit the proliferation response of human peripheral blood lymphocytes to phytohemagglutinin and alloantigens
5. Effect of 4-hydroxynonenal on c-myc expression
6. The inhibitory effect of 4-hydroxy-nonenal on DNA polymerases alpha and beta from rat liver and rapidly dividing Yoshida ascites hepatoma
7. Hydroxyalkenals cytotoxic products of lipid peroxidation
8. Disturbance of cell proliferation by two model compounds of lipid peroxidation contradicts causative role in proliferative senescence
9. Polyamines
10. Ornithine decarboxilase - a key regulatory enzyme in normal and neoplastic growth
11. Retinol inhibition of ornithine decarboxylase induction and GI progression in chinese hamster ovary cells
12. Determination of protein: a modification of the Lowry method that gives a linear photometric response
13. Aldehydic products of lipid peroxidation
14. Mouse ornithine decarboxylase. Complete amino acid sequenced deduced from cDNA
15. Recent advances in the biochemistry of polyamines in eukaryotes
16. Measurement of the number of ornithine decarboxylase molecules in rate and mouse tissues under various physiological conditions by binding of radio-labelled alpha-difluoromethylornithine
17. Changes in mouse kidney ornithine decarboxylase activity are brought about by changes in amount of ornithine decarboxylase protein as measured by radioimmunoassay
18. Androgen-regulated ornithine decar-boxylase mRNAs of mouse kidney
19. The mechanism of action of 4-hydroxynonenal in cell injury
20. Differential effect of phorbol esters on c-fos, c-myc and ornithine decarboxylase gene expression in mouse skin in vivo
21. 4-hydroxyalkenals interaction with purified microtubular protein
22. Separation and characterization of the aldehydic products of lipid peroxidation stimulated by carbon tetrachloride or ADP-iron in isolated rat hepatocytes and rat liver microsomal suspension
23. Lipid peroxidation in hepatomas of different degrees of deviation
24. Occurrence of 4-hydroxyal-kenals in rat tissues determined as pentafluorobenzyl oxime derivatives by gas chromatography-mass spectrometry
25. Formation of aliphatic aldehydes in the plasma and liver of vitamin E deficient rats
26. Lipid peroxidation in animal tumours: a disturbance in the control of cell division?