Anti–B-cell monoclonal antibodies in the treatment of severe B-cell lymphoproliferative syndrome following bone marrow and organ transplantation

New England Journal of Medicine

Volumn 324, Issue 21, 1991, Pages 1451-1456

  Fischer, Alain ^a   Blanche, Stéphane ^a   le Deist, Françoise ^a   Griscelli, Claude ^a   le Bidois, Jérôme ^b   Niaudet, Patrick ^c   Fischer, Anne Marie ^d   Bordigoni, Pierre ^e   Garnier, Jane Luce ^f   Morinet, Frederic ^g   Hirn, Michel ^h  

^a INSERM   (France)

^b Unité de Néphrologie ^*  (France)

^c Départment d'Hématologie ^*  (France)

^d Département d hématologie   (France)

^e HÔPITAL NECKER ENFANTS MALADES   (France)

^f EDOUARD HERRIOT HOSPITAL   (France)

^g SAINT LOUIS HOSPITAL   (France)

^h Immunotech   (France)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE ANTIBODY; MONOCLONAL ANTIBODY;

ADOLESCENT; ADULT; ARTICLE; B LYMPHOCYTE; BONE MARROW TRANSPLANTATION; CHILD; CLINICAL ARTICLE; DRUG EFFICACY; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INFANT; INTRAVENOUS DRUG ADMINISTRATION; LYMPHOPROLIFERATIVE DISEASE; NEUTROPENIA; ORGAN TRANSPLANTATION; PRIORITY JOURNAL; SIDE EFFECT; TRANSPLANTATION;

ADOLESCENT; ADULT; ANTIBODIES, MONOCLONAL; ANTIGENS, DIFFERENTIATION; ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE; B-LYMPHOCYTES; BONE MARROW TRANSPLANTATION; CHILD; CHILD, PRESCHOOL; GRAFT REJECTION; GRAFT VS HOST DISEASE; HUMAN; IMMUNOSUPPRESSION; INFANT; INJECTIONS, INTRAVENOUS; LYMPHOPROLIFERATIVE DISORDERS; MIDDLE AGE; ORGAN TRANSPLANTATION; POSTOPERATIVE COMPLICATIONS;

EID: 0025794063     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM199105233242102     Document Type: Article

References (26)

1. Hanto D.W., Frizzera G., Gajl-Peczalska K.J., Simmons R.L. Epstein–Barr virus, immunodeficiency, and B cell lymphoproliferation. Transplantation 1985; 39:461-472
2. Frizzera G., Hanto D.W., Gajl-Peczalska K.J., et al. Polymorphic diffuse B cell hyperplasias and lymphomas in renal transplant recipients. Cancer Res 1981; 41:4262-4279
3. Schubach W.H., Miller G., Thomas E.D. Epstein–Barr virus genomes are restricted to secondary neoplastic cells following bone marrow transplantation. Blood 1985; 65:535-538
4. Young L., Alfieri C., Hennessy K., et al. Expression of Epstein–Barr virus transformation—associated genes in tissues of patients with EBV lymphoproliferative disease. N Engl J Med 1989; 321:1080-1085
5. Hanto D.W., Birkenbach M., Frizzera G., Gajl-Peczalska K.J., Simmons R.L., Schubach W.H. Confirmation of the heterogeneity of posttransplant Epstein–Barr virus-associated B cell proliferations by immunoglobulin gene rearrangement analyses. Transplantation 1989; 47:458-464
6. Crawford D.H., Mulholland N., Iliescu V., Hawkins R., Powles R. Epstein–Barr virus infection and immunity in bone marrow transplant recipients. Transplantation 1986; 42:50-54
7. Deeg H.J., Storb R., Thomas E.D. Bone marrow transplantation: a review of delayed complications. Br J Haematol 1984; 57:185-208.
8. Shapiro R.S., McClain K., Frizzera G., et al. Epstein–Barr virus associated B cell lymphoproliferative disorders following bone marrow transplantation. Blood 1988; 71:1234-1243
9. Zutter M.M., Martin P.J., Sale G.E., et al. Epstein–Barr virus lymphoproliferation after bone marrow transplantation. Blood 1988; 72:520-529
10. Ash R.C., Casper J.T., Chitambar C.R., et al. Successful allogeneic transplantation of T-cell–depleted bone marrow from closely HLA-matched unrelated donors. N Engl J Med 1990; 322:485-494
11. Fischer A., Griscelli C., Friedrich W., et al. Bone marrow transplantation for immunodeficiencies and osteopetrosis: European survey, 1968–1985. Lancet 1986; 2:1080-1084
12. Ho M., Jaffe R., Miller G., et al. The frequency of Epstein–Barr virus infection and associated lymphoproliferative syndrome after transplantation and its manifestations in children. Transplantation 1988; 45:719-727
13. Starzl T.E., Nalesnick M.A., Porter K.A., et al. Reversibility of lymphomas after lymphoproliferative lesions developing under cyclosporin-steroid therapy. Lancet 1984; 1:583-587
14. Hanto D.W., Frizzera G., Gajl-Peczalska K.J., Balfour H.H. Jr., Simmons R.L., Najarian J.S. Acyclovir therapy of Epstein–Barr virus-induced posttransplant lymphoproliferative diseases. Transplant Proc 1985; 17:89-92.
15. Pirsch J.D., Stratta R.J., Sollinger H.W., et al. Treatment of severe Epstein–Barr virus-induced lymphoproliferative syndrome with ganciclovir: two cases after solid organ transplantation. Am J Med 1989; 86:241-244
16. Shapiro R.S., Chauvenet A., McGuire W., et al. Treatment of B-cell lymphoproliferative disorders with interferon alpha and intravenous gamma globulin. N Engl J Med 1988; 318:1334.
17. Blanche S., Le Deist F., Veber F., et al. Treatment of severe Epstein–Barr virus-induced polyclonal B-lymphocyte proliferation by anti-B-cell monoclonal antibodies. Ann Intern Med 1988; 108:199-203.
18. Fischer A.M., Simon F., Le Deist F., Blanche S., Griscelli C., Fischer A. Prospective study of the occurrence of monoclonal gammapathies following bone marrow transplantation in young children. Transplantation 1990; 49:731-735
19. Jarry A., Cerf-Bensussan N., Brousse N., Guy-Grand D., Muzeau F., Potet F. Same peculiar subset of HML-1( + ) lymphocytes present within normal intestinal epithelium is associated with tumor epithelium of gastrointestinal carcinomas. Gut 1988; 29:1632-1638
20. Perez N., Le Deist F., Chatenoud L., Chanteloup N., Fischer A. In vitro infusion of anti-LFA-1 antibody in HLA nonidentical bone marrow transplantation in children: serum concentrations and biological effects. Bone Marrow Transplant 1989; 4:379-384
21. Fermand J.-P., Gozlan J., Bendelac A., Delauche-Cavallier M.-C., Brouet J.-C., Morinet F. Detection of Epstein–Barr virus in epidermal skin lesions of an immunocompromised patient. Ann Intern Med 1990; 112:511-515
22. Boucheix C., Perrot J.Y., Mirshahi M., et al. A new set of monoclonal antibodies against acute lymphoblastic leukemia. Leuk Res 1985; 9:597-604.
23. Brochier J., Magaud J.P., Cordier G. A monoclonal antibody reactive with non circulating human B lymphocytes. J Immunol Methods 1983; 58:M4. abstract.
24. Fingeroth J.D., Weis J.J., Tedder T.F., et al. Epstein–Barr virus receptor of human B lymphocytes is the C3d receptor CR2. Proc Natl Acad Sci U S A 1984; 81:4510-4514
25. Meyers J.D., Reed E.C., Shepp D.H., et al. Acyclovir for prevention of cytomegalovirus and disease after allogeneic marrow transplantation. N Engl J Med 1988; 318:70-75
26. Thomas J.A., Hotchin N.A., all-day M.J., et al. Immunohistology of Epstein–Barr virus-associated antigens in B cell disorders from immunocompromised individuals. Transplantation 1990; 49:944-953