The horizons of an interdisciplinary synthesis in experimental gerontology

Archives of Gerontology and Geriatrics

Volumn 12, Issue 2-3, 1991, Pages 329-349

  Zs Nagy, Imre ^a  

^a Fritz Verzár International Laboratory for Experimental Gerontology ^*  (Italy)

Author keywords

BCE 001; Centrophenoxine; Membrane hypothesis of aging; Oxygen free radicals; Theoretical gerontology

Indexed keywords

BCE 001; FREE RADICAL; MECLOFENOXATE; OXYGEN RADICAL; UNCLASSIFIED DRUG;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; CELL MEMBRANE; CONFERENCE PAPER; CONTROLLED STUDY; HYPOTHESIS; MEMBRANE PERMEABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; RNA SYNTHESIS;

ANIMALIA;

EID: 0025778703     PISSN: 01674943     EISSN: None     Source Type: Journal    
DOI: 10.1016/0167-4943(91)90038-R     Document Type: Article

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5. Kinetics of the lactate dehydrogenase reaction in high-viscosity media
6. Brain water and aging
7. Hydroxyl free radical formation from hydrogen peroxide by ferrous iron-nucleotide complexes
8. Formation of long-lived hydroxyl free radical adducts of proline and hydroxyproline in a Fenton reaction
9. The biology of oxygen radicals
10. Age-related changes in the function of somatic membrane potassium channels of neurons in the mollusc Lymnaea stagnalis
11. Regulation of glutamine synthetase, aspartokinase, and total protein turnover in Klebsiella aerogenes
12. Effects of centrophenoxine on body composition and some biochemical parameters of demented elderly people as revealed in a double blind clinical trial
13. + discrimination ratio
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15. Prolongation of the normal life span by radiation protection chemicals
16. The free radical theory of aging: the effect of age on serum mercaptan levels
17. Mutation, cancer and aging
18. Prolongation of the normal life span and inhibition of spontaneous cancer by antioxidants
19. The aging process
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23. Pressure volume relation for cylindrical tubes with elastometric walls: the human aorta
24. Correlation between the biliary excretion of ouabain and the lateral mobility of hepatocyte plasma membrane proteins in the rat
25. The striatal dopamine dependency of life span in male rats
26. Free radicals and inflammation: protection of synovial fluid by superoxide dismutase
27. Superoxide and inflammation: a mechanism for the anti-inflammatory activity of superoxide dismutase
28. Alterations in the molecular weight distribution of proteins in rat brain synaptosomes during aging and centrophenoxine treatment
29. Alterations of the synaptosomal membrane microviscosity in the brain cortex of rats during aging and centrophenoxine treatment
30. Spin label studies on synaptosomal membranes of rat brain cortex during aging
31. Do mitochondria produce oxygen radicals in vivo?
32. The metabolic fate of mitochondrial hydrogen peroxide
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35. Radiation carcinogenesis from a membrane perspective
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38. Effects of aging on neuronal electrical membrane properties
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40. Changes in expression of superoxide dismutase and catalase as a function of age and dietary restriction
41. Age differences in the water content of the body as related to basal oxygen consumption in males
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52. The theoretical background and cellular autoregulation of biological waste product formation
53. Functional consequences of free radical damage to cell membranes
54. On the role of intracellular physicochemistry in the quantitative gene expression during aging and the effect of centrophenoxine
55. Centrophenoxine as OH' free radical scavenger
56. A review on the recent advances in the membrane hypothesis of aging
57. Hydroxyl free radical reactions with amino acids and proteins studied by electron spin resonance spectroscopy and spin trapping
58. Electron spin resonance spectroscopic demonstration of the hydroxyl free radical scavenger properties of dimethylaminoethanol in spin trapping experiments confirming the molecular basis for the biological effects of centrophenoxine
59. ESR spin trapping studies on the OH' free radical reactions of idebenone
60. On the role of cross-linking of cellular proteins in aging
61. Centrophenoxine increases the rates of total and mRNA synthesis in the brain cortex of old rats: an explanation of its action in terms of the membrane hypothesis of aging
62. +-uptake and release
63. An automated method for measuring lateral mobility of proteins in the plasma membrane of cells in compact tissues by means of fluorescence recovery after photobleaching
64. Verification of the membrane hypothesis of aging on the identified giant neurons of the snail Lymnaea stagnalis L. (Gastropoda, Pulmonata) by a combined application of intracellular electrophysiology and X-ray microanalysis
65. Age-dependent decrease of the lateral diffusion constant of proteins in the plasma membrane of hepatocytes as revealed by fluorescence recovery after photobleaching in tissue smears
66. Age-estimations of rats based on the average lateral diffusion constant of hepatocyte membrane proteins as revealed by fluorescence recovery after photobleaching
67. Age-dependent changes in the osmometric behavior of rat brain and liver
68. Dysdifferentiation hypothesis of aging and cancer: a comparison with the membrane hypothesis of aging
69. Language Deficits in Depression: Comparisons with SDAT and Normal Aging
70. Effect of centrophenoxine and BCE-001 treatment on the lateral diffusion constant of proteins in the hepatocyte membrane as revealed by fluorescence recovery after photobleaching in rat liver smears