Organization and structure of wild rabbit χ2 genes: implications for regulation of kappa expression

Research in Immunology

Volumn 142, Issue 3, 1991, Pages 191-197

  Ayadi, H ^a,b   Marche, P N ^a   El Gaaied, A ^c   Liebe Gris, C ^a   Cazenave, P A ^a  

^a SORBONNE UNIVERSITÉ   (France)

^b UNIVERSITY OF SFAX   (Tunisia)

^c FACULTÉ DES SCIENCES DE TUNIS   (Tunisia)

Author keywords

Allotypy; basMutant; Evolution; Genome; Immunoglobulin; Kappa chain; Kappa 2 genes; Rabbit

Indexed keywords

IMMUNOGLOBULIN KAPPA CHAIN;

ARTICLE; EVOLUTION; FEMALE; GENE EXPRESSION REGULATION; GENE STRUCTURE; GENETIC CONSERVATION; IMMUNOGLOBULIN GENE; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT;

AMINO ACID SEQUENCE; ANIMAL; ANIMALS, WILD; BASE SEQUENCE; CHROMOSOME MAPPING; DNA; EVOLUTION; GENE EXPRESSION REGULATION; GENES, IMMUNOGLOBULIN; IMMUNOGLOBULINS, KAPPA-CHAIN; MOLECULAR SEQUENCE DATA; RABBITS; SUPPORT, NON-U.S. GOV'T;

EID: 0025777614     PISSN: 09232494     EISSN: None     Source Type: Journal    
DOI: 10.1016/0923-2494(91)90058-Q     Document Type: Article

References (25)

1. Identification of genes for the constant region of rabbit T cell receptor β-chains
2. Rabbit immunoglobulin allotypy: a sixth allele at the b locus (b 95)
3. Genetic polymorphism of rabbit immunoglobulins: description of b98, a ninth allele at the χ b-locus
4. A second rabbit kappa isotype
5. Screening λ gt recombinant clones by hybridization to single plaques in situ
6. Sequence of a cDNA encoding basilea kappa light chains (χ2 isotype) suggests a possible relationship of protein structure to limited expression
7. Presence of χ2 light chain in normal rabbit and as induced auto-anti-allotype antibody in χ1 light chain suppressed subjects
8. Immunoglobulin genes in the feral rabbit
9. A “new” allotypic specificity (A9) of rabbit immunoglobulin
10. Structural analysis of a rabbit immunoglobulin χ2 J-C locus reveals multiple deletions
11. Rabbit immunoglobulin χ gene: structure of a germline b4 allotype J-C locus and evidence for several b4-related sequences in the rabbit genome
12. A genomic gene encoding the b5 rabbit immunoglobulin kappa constant region: implication for latent allotype phenomenon
13. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
14. Multiplicity of constant kappa light chain genes in the rabbit genome: a b4 b4 homozygous rabbit contains a χ-bas gene
15. Cloned human and mouse χ immunoglobulin constant and J regions gene conserve homology in functional segments
16. Variant strain of rabbits lacking immunoglobulin kappa polypeptide
17. The isolation of structural genes from libraries of eucaryotic DNA
18. A variable region gene subfamily encoding T cell receptor β chains is selectively conserved among mammals
19. Interallelic and intergenic conversion events could induce differential evolution of the two rabbit immunoglobulin χ light chain genes
20. Allotypy of the rabbit χ2 light chain: evidence that the χ2 isotype is expressed by all members of the rabbit species
21. χ chain allotypes and isotypes in the rabbit cDNA sequences of clones encoding b9 suggest an evolutionary pathways and possible role of the interdomain disulfide bond in quantitative allotype expression
22. Allotypy of rabbit serum proteins. I. Immunochemical analysis leading to the individualization of seven main allotypes
23. DNA sequencing with chain terminating inhibitors
24. Detection of specific sequences among DNA fragments separated by gel electrophoresis
25. Rapid similarity searches of nucleic acid and protein data banks