Selective purging by human interleukin‐2 activated lymphocytes of bone marrows contaminated with a lymphoma line or autologous leukaemic cells

British Journal of Haematology

Volumn 78, Issue 2, 1991, Pages 197-205

  Gambacorti‐Passerini, Carlo ^a,c   Rivoltini, Licia ^a   Fizzotti, Marco ^c   Rodolfo, Monica ^a   Sensi, Maria Luisa ^a   Castelli, Chiara ^a   Orazi, Attilio ^a   Polli, Nicoletta ^a   Bregni, Marco ^a   Siena, Salvatore ^a   Borin, Lorenza ^b   Pogliani, Enrico ^b   Corneo, Gian Marco ^b   Parmiani, Giorgio ^a  

^a NATIONAL CANCER INSTITUTE   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c UNIVERSITY OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1;

ARTICLE; BONE MARROW PURGING; CLINICAL ARTICLE; HUMAN; HUMAN CELL; LEUKEMIA CELL; LYMPHOKINE ACTIVATED KILLER CELL; LYMPHOMA CELL; PRIORITY JOURNAL;

ACUTE DISEASE; ANIMAL; BONE MARROW; BONE MARROW TRANSPLANTATION; BURKITT LYMPHOMA; CYTOTOXICITY, IMMUNOLOGIC; DNA, NEOPLASM; HUMAN; INTERLEUKIN-2; KILLER CELLS, LYMPHOKINE-ACTIVATED; LEUKEMIA; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MICE; MICE, INBRED BALB C; RECOMBINANT PROTEINS; SUPPORT, NON-U.S. GOV'T; TUMOR CELLS, CULTURED; TUMOR STEM CELL ASSAY;

EID: 0025773602     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.1991.tb04416.x     Document Type: Article

References (32)

1. Lymphokine‐activated killer cell lysis of human neuroblastoma cells: a model for purging tumour cells from bone marrow
2. Clonal analysis of cytotoxic T‐lymphocytes response to autologous human metastatic melanoma
3. Inhibition of pluripotent hematopoietic stem cells of bone marrow by large granular lymphocytes
4. Immunoglobulin secretion by cell lines derived from African and American undifferentiated lymphomas of Burkitt's and non Burkitt's type
5. Elimination of clonogenic tumor cells from human bone marrow using a combination of monoclonal antibody:ricin A chain conjugates
6. Minimal residual disease in acute lymphoblastic leukemia detected by immune selection and gene rearrangement analysis
7. The suppressive influence of human tumor necrosis factor on bone marrow hematopoietic progenitor cells from normal donors and patients with leukemia: synergism of TNF and interferon‐gamma
8. The T‐cell CD2 determinant mediates inhibition of erythropoiesis by the lymphokine cascade
9. Autologous bone marrow transplantation. Current status and future directions
10. Inhibition of bone marrow colony formation by human natural killer cells and by natural killer cell‐derived colony‐inhibiting activity
11. Graft versus leukemia effect in man: the relapse of acute leukemia is lower after allogeneic than after syngeneic marrow transplantation
12. A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity
13. Tumor localization of adoptively transferred Indium‐111 labelled tumour infiltrating lymphocytes in patients with metastatic melanoma
14. Induction and persistence of complete remission in a resistant acute myeloid leukemia patient after treatment with recombinant interleukin‐2
15. Differential lysis of melanoma clones by autologous recombinant interleukin 2‐activated lymphocytes. Relationship with spontaneous resistance to doxorubicin (Dx)
16. Susceptibility of human and murine drug‐resistant tumor cells to the lytic activity of rIL2‐activated lymphocytes (LAK)
17. Lymphokine activated killer cell phenomenon. I. Lysis of natural killer‐resistant fresh solid tumor cells by interleukin 2‐activated autologous human peripheral blood lymphocytes
18. Lymphokine‐activated killer cell purging of leukemia cells from bone marrow prior to syngeneic transplantation
19. Induction of NK cell activity against fresh human leukemia in culture with interleukin 2
20. The molecular control of cell division, differentiation commitment and maturation in haematopoietic cells
21. Cytotoxicity of interleukin 2‐activated lymphocytes for leukemia and lymphoma cells
22. Large granular lymphocytes have a promoting activity on human peripheral blood erythroid burst forming units
23. The structure of the human immunoglobulin μ locus: characterization of embryonic and rearranged J and D genes
24. A progress report on the treatment of 157 patients with advanced cancer using lymphokine activater killer cells and interleukin‐2 or high dose interleukin‐2 alone
25. Effects of in vitro purging with 4‐hydroperoxycyclophosphamide on the hematopoietic and microenvironmental elements of human bone marrow
26. Specific recognition of human leukemic cells by allogeneic T cell lines
27. Influence of acute and chronic graft‐versus‐host disease on relapse and survival after bone marrow transplantation from HLA‐identical siblings as treatment of acute and chronic leukemia
28. Lymphokine‐activated killer cells selectively kill tumor cells in bone marrow without compromising bone marrow stem cell function in vitro
29. + lymphocytes
30. Continuous culture of T cells cytotoxic for autologous human leukaemia cells