Increases in cytosolic Ca++ down regulate thyrotropin receptor gene expression by a mechanism different from the cAMP signal

Biochemical and Biophysical Research Communications

Volumn 176, Issue 1, 1991, Pages 94-101

  Saji, Motoyasu ^a   Ikuyama, Shoichiro ^a   Akamizu, Takashi ^a   Kohn, Leonard D ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; THYROTROPIN; THYROTROPIN RECEPTOR;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; GENE EXPRESSION REGULATION; NONHUMAN; PRIORITY JOURNAL; RAT; THYROID CELL;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ANIMAL; CALCIUM; CALMODULIN; CELL LINE; CHOLERA TOXIN; CLONING, MOLECULAR; CYCLIC AMP; CYTOSOL; DOWN-REGULATION; EDETIC ACID; EGTAZIC ACID; FORSKOLIN; IONOMYCIN; KINETICS; RATS; RECEPTORS, THYROTROPIN; RNA; SIGNAL TRANSDUCTION; SULFONAMIDES; THYROID GLAND; TRANSFECTION;

ANIMALIA;

EID: 0025772607     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/0006-291X(91)90894-D     Document Type: Article

References (16)

1. 8-Diethylamino-octyl-3,4,5-trimethoxybenzoate, a calcium store blocker, increases calcium influx, inhibits alpha-1 adrenergic receptor calcium mobilization, and alters iodide transport in FRTL-5 rat thyroid cells.
2. Regulation of prostaglandin synthesis by thyrotropin, insulin or insulin-like growth factor-I, and serum in FRTL-5 rat thyroid cells.