Elevated P53 expression correlates with a history of heavy smoking in squamous cell carcinoma of the head and neck

British Journal of Cancer

Volumn 64, Issue 3, 1991, Pages 573-577

  Field, J K ^a   Spandidos, D A ^b   Malliri, A ^b   Gosney, J R ^c   Yiagnisis, M ^b   Stell, P M ^c  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b INSTITUTE OF BIOLOGY   (Greece)

^c ROYAL LIVERPOOL UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HEAD AND NECK CANCER; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; SMOKING; SQUAMOUS CELL CARCINOMA; TUMOR SUPPRESSOR GENE;

CARCINOMA, SQUAMOUS CELL; CELL LINE; GENE EXPRESSION; GENES, P53; HEAD AND NECK NEOPLASMS; HUMAN; PROTEIN P53; SMOKING; SMOKING CESSATION; SUPPORT, NON-U.S. GOV'T;

EID: 0025738297     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.1991.352     Document Type: Article

References (39)

1. ARMITAGE, P. & BERRY, G. (1987). In Statistical Methods in Medical Research. 2nd ed. Blackwell Scientific Publications, pp. 436-437
2. BAKER, S.J., FEARON, E.R., NIGRO, J.M. & 9 others (1989). Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science, 244, 217
3. BANKS, L., MATLASHEWSKI, G. & CRAWFORD, L. (1986). Isolation of human-p53-specific monoclonal antibodies and their use in the studies of human p53 expression. Eur. J. Biochem., 159, 529
4. BARTEK, J., IGGO, R., GANNON, J. & LANE, D. (1990). Genetic and immunochemical analysis of mutant p53 in human breast cancer. Oncogene, 5, 893
5. CATTORETTI, G., RILKE, F., ANDREOLA, S., D’AMATO, L. & DELIA, D. (1988). P53 expression in breast cancer. Int. J. Cancer, 41, 178
6. CHIBA, I., TAKAHASHI, T., NAU, M. & 11 others (1990). Mutations in the p53 gene are frequent in primary, resected non-small cell lung cancer. Oncogene, 5, 1603
7. CRAWFORD, L.V., PIM, D C., GURNEY, E G., GOODFELLOW, P. & TAYLOR-PAPADIMITRIOU, J. (1981). Detection of a common feature in several human tumor cell lines -a 53, 000 Dalton protein. Proc. Natl Acad. Sci. USA, 78, 41
8. DIPPOLD, W.G., JAY, G., DELEO, A.B., KHOURY, G. & OLD, L.J. (1981). P53 transformation-related protein: detection by monoclonal antibody in mouse and human cells. Proc. Natl Acad. Sci. USA, 78, 1695
9. DOLL, R. & PETO, R. (1976). Mortality in relation to smoking: 20 years observations on male doctors. Br. Med. J., 2, 1525
10. FIELD, J.K., LAMOTHE, A. & SPANDIDOS, D.A. (1986). Clinical relevance of oncogene expression in head and neck tumours. Anticancer Res., 6, 595
11. FIELD, J.K. & SPANDIDOS, D.A. (1987). Expression of oncogenes in human tumours with special reference to the head and neck region. J. Oral Pathol., 16, 97
12. FIELD, J.K., SPANDIDOS, D.A., STEEL, P.M., VAUGHAN, E.D., EVAN, G.I. & MOORE, J.P. (1989). Elevated expression of the c-myc oncoprotein correlates with poor prognosis in head and neck squamous cell carcinoma. Oncogene, 4, 1463
13. FIELD, J.K. & SPANDIDOS, D.A. (1990). Expression of ras and myc oncogenes in human solid tumours and their relevance in diagnosis and prognosis. A review. Anticancer Res., 10, 1
14. FIELD, J.K. (1991). The Biology of Oncogenes. Oral cancer and detection of patients and lesions at risk. Johnson, N.W. (ed.). pp 257-293, Cambridge University Press
15. FIELD, J.K., YIAGNISIS, M., SPANDIDOS, D.A. & 4 others (1991). Low levels of ras p21 oncogene expression correlates with clincial outcome in head and neck squamous cell carcinoma. Eur. J. Surg. Oncol, (in press)
16. FINLAY, C.A., HINDS, P.W. & LEVINE, A.J. (1989). The p53 ProtoOncogene can act as a suppressor of transformation. Cell, 57, 1083
17. FURTH, M.E., DAVIS, I.J., FLEURDELYS, B. & SCOLNICK, E.M. (1982). Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family. J. Virol., 43, 294
18. HARLOW, E., CRAWFORD, L.V., PIM, D.C. & WILLIAMSON, N.M. (1981). Monoclonal antibodies specific for simian virus 40 tumour antigens. J. Virol., 39, 861
19. HARLOW, E., WILLIAMSON, N., RALSTON, R., HELFMAN, D. & ADAMS, T. (1985). Molecular cloning and in vitro expression of a cDNA clone for human cellular tumour antigen p53. Mol. Cell Biol., 5, 1601
20. HINDS, P., FINLAY, C. & LEVINE, A.J. (1989). Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation. J. Virol., 63, 739
21. HSU, S.M., RAINE, L. & FANGER, H. (1981). Use of avidin-biotin peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabelled antibody (PAP) procedures. J. Histochem. Cytochem., 29, 577
22. IGGO, R., GATTER, K., BARTER, J., LANE, D. & HARRIS, A.L. (1990). Increased expression of mutant forms of p53 oncogene in primary lung cancer. Lancet, 675
23. KAPLAN, E.L. & MEIER, P. (1958). Nonparametric estimation from complete observation. J. Amer. Stat. Assoc., 53, 457
24. LANE, D.P. & CRAWFORD, L.V. (1979). T antigen is bound to a host protein in SV40-transformed cells. Nature, 278, 261
25. LANE, D.P. & BENCHIMOL, S. (1990). P53: oncogene or anti-oncogene? Genes & Develop., 4, 1
26. MYERS, E.N. & SUEN, J.Y. (1989). Cancer of the Head and Neck. 2nd Edition. Churchill Livingstone Inc: New York
27. MAZUR, M. & GLICKMAN, B. (1988). Sequence specificity of mutations induced by benzy[a]pyrene-7, 8-diol-9, 10-epoxide at endogenous part gene in CHO cells. Com. Cell. Mol. Gen., 14, 393
28. NIGRO, J.M., BAKER, S.J., PREISINGER, A.C. & 13 Others (1989). Mutations in the p53 gene occur in diverse human tumour types. Nature, 342, 705
29. PARADA, L.F., LAND, H., WEINBURGH, R.A., WOLF, D. & ROTTER, V. (1984). Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation. Nature, 312, 649
30. RUMSBY, G., CARTER, R.L. & GUSTERSON, B.A. (1990). Low incidence of ras oncogene activation in human squamous cell carcinomas. Br. J. Cancer, 61, 365
31. SARANATH, D., PANCHAL, R.G., NAIR, R., METHA, A.R. & DES, M.G. (1989). Oncogene amplification in squamous cell carcinoma of the oral cavity. Jpn. J. Cancer Res., 80, 430
32. SCHMIDT, W. & POPHAM, R.E. (1981). The role of drinking and smoking in mortality from cancer and other causes in male alcoholics. Cancer, 47, 1030
33. SHENG, Z.M., BARROIS, M., KLIJANIENKO, J., MICHEAU, C., RICHARD, J.M. & RIOU, G. (1990). Analysis of the c-Ha-ras-l gene for deletion, mutation, amplification and expression in lymph node metastases of human head and neck carcinomas. Br. J. Cancer, 62, 398
34. SILVERMAN, S. & GRIFFITH, M. (1972). Smoking characteristics of patients with oral carcinoma and risk for second oral primary carcinoma. J. Am. Dent. Assoc., 85, 637
35. STELL, P.M. (1972). Smoking and laryngeal cancer. Lancet, 1, 617
36. TAKAHASHI, T., D’AMICO, D., CHIBA, I., BUCHHABEN, D. & MINNA, J. (1989). Identification of intronic mutations as an alternative mechanism for p53 inactivation in lung cancer. J. Clin. Invest., 86, 363
37. UNION INTERNATIONALE CONTRE LE CANCER TNM CLASSIFICATION OF MALIGNANT TUMOURS (1987). Hermanek, P. & Fobin, L. (eds), Sringer Verlag: Heidelberg
38. WADE-EVANS, A. & JENKINS, J.R. (1985). Precise epitope mapping the the murine transformation-associated protein, p53. EMBO J., 4, 699
39. WYNDER, E.L. & STELLMAN, S.D. (1977). Comparative epidemiology of tobacco-related cancers. Cancer Res., 37, 4608