Milbemycin synthesis: synthesis of 6β-hydroxy-3,4-dihydromilbemycin E

Tetrahedron Letters

Volumn 32, Issue 20, 1991, Pages 2269-2272

  Karim, Sufia ^a   Parmee, Emma R ^a   Thomas, Eric J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

furan oxidation; macrocyclisation; Milbemycin; Robinson annelation; spiroacetal.

Indexed keywords

3,4 DIHYDRO 6BETA HYDROXYMILBEMYCIN E; ANTHELMINTIC AGENT; MILBEMYCIN G; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; PRIORITY JOURNAL;

EID: 0025735747     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)79699-7     Document Type: Article

References (19)

1. A directed aldol approach to (+)-milbemycin ?3
2. Total synthesis of (+)-milbemycin (?3)
3. Progress in natural product chemistry by the chiron and related approaches - synthesis of avermectin B1a
4. Total Synthesis of Avermectin B1a: Final Coupling Reactions and the Total Synthesis of Avermectin B1a Aglycone
5. A total synthesis of milbemycin E
6. Regio- and Stereoselective Oxidation of Ene-Type Chlorinated Olefins
7. Synthesis of a macrocyclic analogue of milbemycin ?1; X-ray structure of (1RS, 4RS, 6SR, 7SR, 19RS)-(10Z, 12E, 16E)-6,16-dimethyl-9-hydroxy-7-methoxy-10-methoxycarbonyl-2-oxatricyclo[17.3.1.04,9]tricosa-10,12,16-trien-3-one