Synthesis and Anti-HIV Activity of 2-, 3-, and 4-Substituted Analogues of 1-[(2-Hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT)

Journal of Medicinal Chemistry

Volumn 34, Issue 4, 1991, Pages 1394-1399

  Tanaka, Hirotnichi ^a   Miyasaka, Tadashi ^a   Baba, Masanori ^b   Shigeta, Shiro ^b   Ubasawa, Masaru ^c   Takashima, Hideaki ^c   Sekiya, Kouichi ^c   Nitta, Issei ^c   Walker, Richard T ^d   De Clercq, Erik ^e  

^a SHOWA UNIVERSITY   (Japan)

^b FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^c MITSUBISHI CHEMICAL CORPORATION   (Japan)

^d UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^e REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

1 [(2 HYDROXYETHOXY)METHYL] 6 (PHENYLTHIO)THYMINE; 1 [(2 HYDROXYETHOXY)METHYL] 6 PHENYLTHIO 2 THIOTHYMINE; ANTIVIRUS AGENT; THYMINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL;

ANTIVIRAL AGENTS; CELL LINE; CELLS, CULTURED; COMPARATIVE STUDY; HIV-1; HIV-2; HUMAN; INDICATORS AND REAGENTS; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; THYMINE;

EID: 0025734369     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm00108a023     Document Type: Article

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