-
1
-
-
0021741593
-
Cyclopentenylur-idine and cyclopentenylcytidine analogues as inhibitors of uridine-cytidine kinase
-
Lim, M.-L., Moyer, J. D., Cysk, R. L., and Marquez, V. D. Cyclopentenylur-idine and cyclopentenylcytidine analogues as inhibitors of uridine-cytidine kinase. J. Med. Chem., 27: 1536–1538, 1984.
-
(1984)
J. Med. Chem.
, vol.27
, pp. 1536-1538
-
-
Moyer, M.-L.1
Cysk, R.L.2
Marquez, V.D.3
-
2
-
-
84965806169
-
Cyclopentenyl cytosine. A neplanocin analogue with preclinical antitumor and antiviral activity
-
Driscoll, J. S., Marquez, V. E., and Treanor, S. P. Cyclopentenyl cytosine. A neplanocin analogue with preclinical antitumor and antiviral activity. Proc. Am. Assoc. Cancer Res., 28: 328, 1987.
-
(1987)
Proc. Am. Assoc. Cancer Res.
, vol.28
, pp. 328
-
-
Driscoll, J.S.1
Marquez, V.E.2
Treanor, S.P.3
-
3
-
-
0023785302
-
Cyclopentenylcytosine: a carbocyclic nucleoside with antitumor and antiviral properties
-
Marquez, V. E., Lim, M.-I., Treanor, S. P., Plowman, J., Priest, M. A., Markovac, A., Khan, M. S., Kaskar, B., and Driscoll, J. S. Cyclopentenylcytosine: a carbocyclic nucleoside with antitumor and antiviral properties. J. Med. Chem., 31: 1687–1694, 1988.
-
(1988)
J. Med. Chem.
, vol.31
, pp. 1687-1694
-
-
Marquez, V.E.1
Lim, M.-I.2
Treanor, S.P.3
Plowman, J.4
Priest, M.A.5
Markovac, A.6
Khan, M.S.7
Kaskar, B.8
Driscoll, J.S.9
-
4
-
-
0022654279
-
Antitumor activity and biochemical effects of cyclopentenyl cytosine in mice
-
Moyer, J. D., Malinowski, N. M., Treanor, S. P., and Marquez, V. E. Antitumor activity and biochemical effects of cyclopentenyl cytosine in mice. Cancer Res., 46: 3325–3329, 1986.
-
(1986)
Cancer Res.
, vol.46
, pp. 3325-3329
-
-
Moyer, J.D.1
Malinowski, N.M.2
Treanor, S.P.3
Marquez, V.E.4
-
5
-
-
0021824470
-
Cyclopentenyl cytidine analogue: an inhibitor of cytidine triphosphate synthesis in human colon carcinoma cells
-
Glazer, R. I., Knode, M. C., Lim, M.-I., and Marquez, V. E. Cyclopentenyl cytidine analogue: an inhibitor of cytidine triphosphate synthesis in human colon carcinoma cells. Biochem. Pharmacol., 34: 2535–2539, 1985.
-
(1985)
Biochem. Pharmacol.
, vol.34
, pp. 2535-2539
-
-
Glazer, R.I.1
Knode, M.C.2
Lim, M.-I.3
Marquez, V.E.4
-
6
-
-
0022523346
-
Induction of differentiation in the human promyelocyte leukemia cell line HL-60 by the cyclopentenyl analogue of cytidine
-
Glazer, R. I., Cohen, M. B., Hartman, K. D., Knode, M. C., Lim, M.-I., and Marquez, V. E. Induction of differentiation in the human promyelocyte leukemia cell line HL-60 by the cyclopentenyl analogue of cytidine. Biochem. Pharmacol., 35: 1841–1848, 1986.
-
(1986)
Biochem. Pharmacol.
, vol.35
, pp. 1841-1848
-
-
Glazer, R.I.1
Cohen, M.B.2
Hartman, K.D.3
Knode, M.C.4
Lim, M.-I.5
Marquez, V.E.6
-
7
-
-
0024570138
-
Cyclopentenylcytosine triphosphate: formation and inhibition of CTP synthetase
-
Kang, G. J., Cooney, D. A., Moyer, J. D., Kelley, J. A., Kim, H.-Y., Marquez, V. E., and Johns, D. G. Cyclopentenylcytosine triphosphate: formation and inhibition of CTP synthetase. J. Biol. Chem., 264: 713–718, 1989.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 713-718
-
-
Kang, G.J.1
Cooney, D.A.2
Moyer, J.D.3
Kelley, J.A.4
Kim, H.-Y.5
Marquez, V.E.6
Johns, D.G.7
-
8
-
-
0026087041
-
Cyclopentenyl cytosine: intraspecies predictions based on rodent plasma and renal kinetics
-
in press
-
Zaharko, D. S., Kelley, J. A., Tomaszewski, J. E., Hegedus, L., and Hartman, N. R. Cyclopentenyl cytosine: intraspecies predictions based on rodent plasma and renal kinetics. Invest. New Drugs, in press, 1990.
-
(1990)
Invest. New Drugs
-
-
Zaharko, D.S.1
Kelley, J.A.2
Tomaszewski, J.E.3
Hegedus, L.4
Hartman, N.R.5
-
9
-
-
0013805757
-
Studies of the enzymatic deamination of cytosine arabinoside-I: Enzyme distribution and species specificity
-
Camiener, G. W., and Smith, C. G. Studies of the enzymatic deamination of cytosine arabinoside-I: Enzyme distribution and species specificity. Biochem. Pharmacol. 14: 1405–1416, 1965.
-
(1965)
Biochem. Pharmacol.
, vol.14
, pp. 1405-1416
-
-
Camiener, G.W.1
Smith, C.G.2
-
11
-
-
0017623708
-
Primate model for the chronic study of intraventricularly or intrathecally administered drug and intracranial pressure
-
Wood, J. H., Poplack, D. G., Bleyer, W. A., and Ommaya, A. K. Primate model for the chronic study of intraventricularly or intrathecally administered drug and intracranial pressure. Science (Washington DC), 195: 499–500, 1977.
-
(1977)
Science (Washington DC)
, vol.195
, pp. 499-500
-
-
Wood, J.H.1
Poplack, D.G.2
Bleyer, W.A.3
Ommaya, A.K.4
-
12
-
-
0021233114
-
Cytosine arabinoside cerebrospinal fluid kinetics
-
Zimm, S., Collins, J. M., Miser, J., Chatterji, D., and Poplack, D. Cytosine arabinoside cerebrospinal fluid kinetics. Clin. Pharmacol. Ther., 35: 826–830, 1984.
-
(1984)
Clin. Pharmacol. Ther.
, vol.35
, pp. 826-830
-
-
Zimm, S.1
Collins, J.M.2
Miser, J.3
Chatterji, D.4
Poplack, D.5
-
13
-
-
0018563907
-
MLAB: a mathematical modeling tool
-
Knott, G. D. MLAB: a mathematical modeling tool. Comput. Programs Biomed., 10: 271–280, 1979.
-
(1979)
Comput. Programs Biomed.
, vol.10
, pp. 271-280
-
-
Knott, G.D.1
-
14
-
-
0018091195
-
Application of Akaike's information criterion (AIQ in the evaluation of linear pharmacokinetic equations. J. Pharmacokinet
-
Yamaoka, K., Nakagawa, T., and Uno, T. Application of Akaike's information criterion (AIQ in the evaluation of linear pharmacokinetic equations. J. Pharmacokinet. Biopharm., 6: 165–175, 1978.
-
(1978)
Biopharm.
, vol.6
, pp. 165-175
-
-
Yamaoka, K.1
Nakagawa, T.2
Uno, T.3
-
15
-
-
0004061014
-
Estimation of areas
-
In:, Ed. 2, New York: Marcel Dekker, Inc.
-
Gibaldi, M., and Perrier, D. Estimation of areas. In: Pharmacokinetics, Ed. 2, pp. 445–449. New York: Marcel Dekker, Inc., 1982.
-
(1982)
Pharmacokinetics
, pp. 445-449
-
-
Gibaldi, M.1
Perrier, D.2
-
16
-
-
0019974468
-
Noncompartmental determination of steady state volume of distribution for any mode of administration
-
Perrier, D., and Mayersohn, M. Noncompartmental determination of steady state volume of distribution for any mode of administration. J. Pharm Sci., 77: 372–373, 1982.
-
(1982)
J. Pharm Sci.
, vol.77
, pp. 372-373
-
-
Perrier, D.1
Mayersohn, M.2
-
17
-
-
0017736383
-
A primate model for study of methotrexate pharmacokinetics in the central nervous system
-
Poplack, D. G., Bleyer, W. A., Wood, J. H., Kostolich, M., Savitch, J. L., and Ommaya, A. K. A primate model for study of methotrexate pharmacokinetics in the central nervous system. Cancer Res., 37: 1982–1985, 1977.
-
(1977)
Cancer Res.
, vol.37
, pp. 1982-1985
-
-
Poplack, D.G.1
Bleyer, W.A.2
Wood, J.H.3
Kostolich, M.4
Savitch, J.L.5
Ommaya, A.K.6
-
18
-
-
0023780428
-
Preclinical pharmacology of arabinosyl-5-azacytidine in nonhuman primates
-
Heideman, R. L., Balis, F. M., McCully, C., and Poplack, D. G. Preclinical pharmacology of arabinosyl-5-azacytidine in nonhuman primates. Cancer Res., 48: 4294–4298, 1988.
-
(1988)
Cancer Res.
, vol.48
, pp. 4294-4298
-
-
Heideman, R.L.1
Balis, F.M.2
McCully, C.3
Poplack, D.G.4
-
19
-
-
0022572075
-
Relations of preclinical toxicology to findings in early clinical trials
-
Grieshaber, C. K., and Marsoni, S. Relations of preclinical toxicology to findings in early clinical trials. Cancer Treat. Rep., 70: 65–72, 1986.
-
(1986)
Cancer Treat. Rep.
, vol.70
, pp. 65-72
-
-
Grieshaber, C.K.1
Marsoni, S.2
-
20
-
-
0022542904
-
Pharmacology and toxicity of high-dose cytarabine by 72-hour continuous infusion
-
Donehower, R. C., Karp, J. E., and Burke, P. J. Pharmacology and toxicity of high-dose cytarabine by 72-hour continuous infusion. Cancer Treat. Rep., 70: 1059–1065, 1986.
-
(1986)
Cancer Treat. Rep.
, vol.70
, pp. 1059-1065
-
-
Donehower, R.C.1
Karp, J.E.2
Burke, P.J.3
-
21
-
-
0023518453
-
The disposition and metabolism of 2′, 3′-dideoxycytidine, an in vitro inhibitor of HTLV-III infectivity, in mice and monkeys
-
Kelley, J. A., Litterst, C. L., Roth, J. S., Vistica, D. T., Poplack, D. G., Cooney, D. A., Nadkarni, M., Balis, F. M., Broder, S. B., and Johns, D. G. The disposition and metabolism of 2′, 3′-dideoxycytidine, an in vitro inhibitor of HTLV-III infectivity, in mice and monkeys. Drug Metab. Dispos. 15: 595–601, 1987.
-
(1987)
Drug Metab. Dispos.
, vol.15
, pp. 595-601
-
-
Kelley, J.A.1
Litterst, C.L.2
Roth, J.S.3
Vistica, D.T.4
Poplack, D.G.5
Cooney, D.A.6
Nadkarni, M.7
Balis, F.M.8
Broder, S.B.9
Johns, D.G.10
-
22
-
-
0024265003
-
Pharmacokinetics of 2′, 3′-dideoxycytidine in patients with AIDS and related disorders
-
Klecker, R. W., Collins, J. M., Yarchoan, R. C., Thomas, R., McAtee, N., Broder, S., and Myers, C. E. Pharmacokinetics of 2′, 3′-dideoxycytidine in patients with AIDS and related disorders. J. Clin. Pharmacol., 28: 837–842, 1988.
-
(1988)
, vol.28
, pp. 837-842
-
-
Klecker, R.W.1
Collins, J.M.2
Yarchoan, R.C.3
Thomas, R.4
McAtee, N.5
Broder, S.6
Myers, C.E.7
-
23
-
-
0022569778
-
Potential roles for preclinical pharmacology in phase I clinical trials
-
Collins, J. M., Zaharko, D. S., Dedrick, R. L., and Chabner, B. A. Potential roles for preclinical pharmacology in phase I clinical trials. Cancer Treat. Rep., 70: 73–80, 1986.
-
(1986)
Cancer Treat. Rep.
, vol.70
, pp. 73-80
-
-
Collins, J.M.1
Zaharko, D.S.2
Dedrick, R.L.3
Chabner, B.A.4
-
24
-
-
0023898828
-
Pyrimidine dideoxyribonucleosides: selectivity of penetration into cerebrospinal fluid
-
Collins, J. M., Klecker, R. W., Kelley, J. A., Roth, J. S., McCully, C. L., Balis, F. M., and Poplack, D. G. Pyrimidine dideoxyribonucleosides: selectivity of penetration into cerebrospinal fluid. J. Pharmacol. Exp. Ther., 245: 466–470, 1988.
-
(1988)
J. Pharmacol. Exp. Ther.
, vol.245
, pp. 466-470
-
-
Collins, J.M.1
Klecker, R.W.2
Kelley, J.A.3
Roth, J.S.4
McCully, C.L.5
Balis, F.M.6
Poplack, D.G.7
-
25
-
-
84965839696
-
Mechanism of action of cyclopentenyl cytosine and biochemical modulation of cytosine arabinoside
-
Grem, J. L., and Allegra, C. J. Mechanism of action of cyclopentenyl cytosine and biochemical modulation of cytosine arabinoside. Proc. Am. Assoc. Cancer Res., 31: 421, 1990.
-
(1990)
Proc. Am. Assoc. Cancer Res.
, vol.31
, pp. 421
-
-
Grem, J.L.1
Allegra, C.J.2
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