Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 87, Issue 24, 1990, Pages 10043-10047

  Radomski, M W ^a,b   Palmer, R M J ^a   Moncada, S ^a  

^a WELLCOME RESEARCH LABORATORIES   (United Kingdom)

^b MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

Author keywords

Cytokines; Endotoxin; Steroids

Indexed keywords

CORTODOXONE; DEXAMETHASONE; HYDROCORTISONE; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ARTICLE; ENDOTHELIUM CELL; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; SWINE; VASCULAR ENDOTHELIUM;

AMINO ACID OXIDOREDUCTASES; ANIMAL; AORTA; BRADYKININ; CALCIUM; CELLS, CULTURED; COLLAGEN; CYCLOHEXIMIDE; ENDOTHELIUM, VASCULAR; ENZYME INDUCTION; GLUCOCORTICOIDS; INTERFERON-GAMMA, RECOMBINANT; KINETICS; LIPOPOLYSACCHARIDES; NITRIC OXIDE; NITRIC-OXIDE SYNTHASE; PLATELET AGGREGATION; SWINE;

ANIMALIA; SUS SCROFA;

EID: 0025672648     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.87.24.10043     Document Type: Article

References (17)

1. Palmer, R. M. J., Ferrige, A. G. & Moncada, S. (1987) Nature (London) 327, 524-526.
2. Palmer, R. M. J., Ashton, D. S. & Moncada, S. (1988) Nature (London) 333, 664-666.
3. Hibbs, J. B., Jr., Taintor, R. R., Vavrin, Z. & Rachlin, E. M. (1988) Biochem. Biophys. Res. Commun. 157, 87-94.
4. Marietta, M. A., Yoon, P. S., lyengar, R., Leaf, C. D. & Wishnok, J. S. (1988) Biochemistry 27, 8706-8711.
5. Stuehr, D., Gross, S., Sakuma, I., Levi, R. & Nathan, C. (1989) J. Exp. Med. 169, 1011-1020.
6. Knowles, R. G., Palacios, M., Palmer, R. M. J. & Moncada, S. (1989) Proc. Natl. Acad. Sci. USA 86, 5159-5162.
7. McCall, T. B., Boughton-Smith, N. K., Palmer, R. M. J., Whittle, B. J. R. & Moncada, S. (1989) Biochem. J. 261, 293-296.
8. Palacios, M., Knowles, R. G., Palmer, R. M. J. & Moncada, S. (1989) Biochem. Biophys. Res. Commun. 165, 802-809.
9. Radomski, M. W., Palmer, R. M. J. & Moncada, S. (1990) Proc. Natl. Acad. Sci. USA 87, 5193-5197.
10. Billiar, T. R., Curran, R. D., Stuehr, D. J., West, M. A., Bentz, B. G. & Simmons, R. L. (1989) J. Exp. Med. 169, 1467-1472.
11. Billiar, T. R., Curran, R. D., Stuehr, D. J., Stadler, J., Sim mons, R. L. & Murrary, S. A. (1990) Biochem. Biophys. Res. Commun. 168, 1034-1040.
12. Palmer, R. M. J. & Moncada, S. (1989)Biochem. Biophys. Res. Commun. 158, 348-352.
13. Mayer, B., Schmidt, K., Humbert, P. & Bohme, E. (1989) Biochem. Biophys. Res. Commun. 164, 678-685.
14. Busse, R. & Mulsch, A. (1990) FEBS Lett. 265, 133-136.
15. Amber, I. J., Hibbs, J. B., Jr., Taintor, R. R. & Vavrin, Z. (1988) J. Leukocyte Biol. 43, 187-192.
16. Tayeh, M. A. & Marietta. M. A. (1989) J. Biol. Chem. 264, 19654-19658.
17. Kwon, N. S., Nathan, C. F. & Stuehr, D. J. (1989) J. Biol. Chem. 264, 20496-20501.