Evidence for impaired t cell dna methylation in systemic lupus erythematosus and rheumatoid arthritis

Arthritis & Rheumatism

Volumn 33, Issue 11, 1990, Pages 1665-1673

  Richardson, Bruce ^a,b   Scheinbart, Lee ^a,b   Strahler, John ^a,b   Gross, Laura ^a,b   Hanash, Samir ^a,b   Johnson, Marcia ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; METHYLTRANSFERASE;

ADULT; ARTICLE; AUTOIMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE;

ADULT; AGED; ARTHRITIS, RHEUMATOID; AUTOIMMUNITY; COMPARATIVE STUDY; DNA; DNA MODIFICATION METHYLASES; FEMALE; HUMAN; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; METHYLATION; MIDDLE AGE; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES;

EID: 0025666735     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.1780331109     Document Type: Article

References (47)

1. DNA methylation and gene activity.
2. DNA methylation and gene activity.
3. The inheritance of epigenetic defects.
4. DN. methylation and gene expression, DNA Methylation
5. Gen. activation by 5‐azacytidine, DNA Methylation
6. Effect of an inhibitor of DNA methylation on T cells.
7. + T cells.
8. Hydralazine and procainamide inhibit T cell DNA methylation and induce autoreactivity.
9. Drug‐induced lupus: clinical and serological studies.
10. Allosuppressor‐ and allo‐helper‐T cells in acute and chronic graft‐vs.‐host (GVH) disease.
11. Chronic progressive polyarthritis and other symptoms of collagen vascular disease induced by graft‐vs‐host reaction.
12. Rheumatoid arthritis: a disease of T‐lymphocyte/macrophage immunoregulation.
13. Class II major histocompatibility antigens and the etiology of systemic lupus erythematosus.
14. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis.
15. The 1982 revised criteria for the classification of systemic lupus erythematosus.
16. Antibodies to Sm in patients with systemic lupus erythematosus: correlation of Sm antibody titers with disease activity and other laboratory parameters.
17. The Subcommittee for Criteria of Remission in Rheumatoid Arthritis of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee: Preliminary criteria for clinical remission in rheumatoid arthritis.
18. Multiple sclerosis: update in diagnosis and review of prognostic factors.
19. Increased immunoglobulin response to γ‐inter‐feron by lymphocytes from patients with systemic lupus erythematosus.
20. Spontaneous release of a factor with properties of T cell growth factor from a continuous line of primate tumor T cells.
21. CD4+ cells treated with DNA methylation inhibitors induce autologous B cell differentiation.
22. Long term instability and molecular mechanism of 5‐azacytidine‐induced DNA hypomethylation in normal and neoplastic tissues in vivo.
23. Kinetics of homologous and heterologous aminoacylation with yeast phenylalanyl transfer ribonucleic acid synthetase.
24. Protein measurement with the Folin phenol reagent.
25. Reversed‐phase ion‐pair liquid chromatographic procedure for the simultaneous analysis of s‐adenosylmethionine, its metabolites and the natural polyamines.
26. Measurement of s‐adenosyl‐1‐methionine levels of SP‐sephadex chromatography.
27. Th. methylation machinery: the DNA methyltransferases
28. Identification of proliferatively active cells by monoclonal antibodies against DNA‐cytosine‐5‐methyltransferase.
29. Measurements of s‐adenosylmethionine and 1‐homocysteine metabolism in cultured human lymphoid cells.
30. Coexpression of T4 and T8 on peripheral blood T cells demonstrated by two‐color fluorescence flow cytometry.
31. DN. methylation in early mammalian development, DNA Methylation
32. Hypomethylation of DNA from benign and malignant human colon neoplasms.
33. Hematologic aspects of systemic lupus erythematosus.
34. Naturally occurring methylation inhibitor: DNA hypothylation and hemoglobin synthesis in human K562 cells.
35. Ultraviolet radiation‐induced metallothionein‐I gene activation is associated with extensive DNA demethylation.
36. Nuclear DNA degradation in lymphocytes of patients with systemic lupus erythematosus.
37. Accumulation of guanine‐cytosine‐enriched low M.W. DNA fragments in lymphocytes of patients with systemic lupus erythematosus.
38. Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs.
39. Specific protection of methylated CpGs in mammalian nuclei.
40. DNA methylation and the regulation of globin gene expression.
41. A molecular basis for MHC class II‐associated autoimmunity.
42. Othe. Effects of cytosine methylation on DNA structure
43. Characterization of T cells bearing HLA‐DR antigens in rheumatoid arthritis.
44. The autologous mixed‐lymphocyte reaction.
45. Studies of rheumatoid synovial fluid lymphocytes.