The assessment of hepatic and peripheral insulin sensitivity in hypertriglyceridemia

Metabolism

Volumn 39, Issue 12, 1990, Pages 1240-1245

  McKane, W R ^a,b,c   Stevens, A B ^a,b,c   Woods, R ^a,b,c   Andrews, W J ^a,b,c   Henry, R W ^a,b,c   Bell, P M ^a,b,c  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b ROYAL VICTORIA HOSPITAL   (United Kingdom)

^c Newtownabbey BT37 9RH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; GLUCOSE; INSULIN;

ADULT; ARTICLE; CLINICAL ARTICLE; FEMALE; HUMAN; HYPERTRIGLYCERIDEMIA; INSULIN RESISTANCE; INSULIN SENSITIVITY; MALE; PRIORITY JOURNAL;

ABSORPTION; ADULT; BLOOD GLUCOSE; C-PEPTIDE; FASTING; FEMALE; GLUCOSE; GLUCOSE TOLERANCE TEST; HUMAN; HYPERTRIGLYCERIDEMIA; INSULIN; INSULIN RESISTANCE; LIPIDS; LIVER; MALE; OSMOLAR CONCENTRATION; SUPPORT, NON-U.S. GOV'T;

EID: 0025647503     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/0026-0495(90)90177-E     Document Type: Article

References (31)

1. Reappraisal of the role of insulin in hypertriglyceridemia
2. Relationship between insulin resistance, insulin secretion, very low density lipoprotein kinetics and plasma triglyceride levels in normotriglyceridemic man
3. Effects of weight reduction on obesity. Studies of lipid and carbohydrate metabolism in normal and hyperlipoproteinemic subjects
4. Resistance to insulin but not to glucose in lean human hypertriglyceridemics
5. Diminished insulin receptors on monocytes and erythrocytes in hypertriglyceridemia
6. Hormonal and substrate responses to a standard meal in normal and hypertriglyceridemic subjects
7. The relationship between insulin secretion and triglyceride concentration in endogenous lipemia
8. Plasma glucose and insulin responses to oral glucose in non-obese subjects and patients with endogenous hypertriglyceridemia
9. Inter-relationships among insulin's antilipolytic and glucoregulatory effects and plasma triglycerides in non-diabetic and diabetic patients with endogenous hypertriglyceridemia
10. The immediate effects of insulin and fructose on the metabolism of the perfused liver
11. Effects of in vivo plasma insulin levels on the relationship between perfusate free fatty acid concentration and triglyceride secretion by perfused rat livers
12. 14 C-glucose into lipids released by the liver
13. Increased lipid synthesis by liver slice in a superfusion system following raised glucose or insulin concentration
14. Diabetic hypertriglyceridemia. Evidence for three clinical syndromes
15. Hyperinsulinaemia and in vivo very low density lipoprotein triglyceride kinetics
16. Hepatic insulin responsiveness in patients with endogenous hypertriglyceridemia
17. Second report on diabetes mellitus
18. Dose-response characteristics for effects of insulin on production and utilization of glucose in man
19. Immunoassay of insulin with insulin-antibody precipitate
20. Radioimmunological determination of human C-peptide in serum
21. Measurement of size and turnover rate of body glucose pool by the isotope dilution method
22. 14 glucose
23. Carbohydrate storage in man: Speculation and some quantitative considerations
24. Peripheral metabolism of glucose and free fatty acids during oral glucose tolerance tests
25. 3H] glucose
26. Mechanisms of insulin resistance in human obesity. Evidence for receptor and postreceptor defects
27. Insulin action in non-insulin dependent diabetes mellitus: The relationship between hepatic and extrahepatic insulin resistance and obesity
28. In vivo kinetics of insulin action on peripheral glucose disposal and hepatic glucose output in normal and obese subjects
29. Differential effects of insulin therapy on hepatic and peripheral insulin sensitivity in type 2 (non-insulin dependent) diabetes
30. Receptor and postreceptor defects contribute to the insulin resistance in noninsulin dependent diabetes mellitus
31. Direct and indirect effects of insulin to inhibit hepatic glucose output in obese subjects