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Volumn 323, Issue 25, 1990, Pages 1740-1744

The effects of a 5-lipoxygenase inhibitor on asthma induced by cold, dry air

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; LIPOXYGENASE INHIBITOR; PLACEBO; ZILEUTON;

EID: 0025647031     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM199012203232505     Document Type: Article
Times cited : (339)

References (33)
  • 2
    • 0019966111 scopus 로고
    • Bronchoconstrictor effects of leukotriene C in humans
    • Weiss JW, Drazen JM, Coles N, et al. Bronchoconstrictor effects of leukotriene C in humans. Science 1982; 216: 196–8.
    • (1982) Science , vol.216 , pp. 196-198
    • Weiss, J.W.1    Drazen, J.M.2    Coles, N.3
  • 3
    • 0021269295 scopus 로고
    • 4, and histamine in normal human subjects
    • Barnes NC, Piper PJ, Costello JF. Comparative effects of inhaled leukotriene C4, leukotriene D4, and histamine in normal human subjects. Thorax 1984; 39: 500–4.
    • (1984) Thorax , vol.39 , pp. 500-504
    • Barnes, N.C.1    Piper, P.J.2    Costello, J.F.3
  • 5
    • 0022459317 scopus 로고
    • 4 and to methacholine in patients with asthma and normal controls
    • Adelroth E, Morris MM, Hargreave FE, O'Byrne PM. Airway responsiveness to leukotrienes C4 and D4 and to methacholine in patients with asthma and normal controls. N Engl J Med 1986; 315: 480–4.
    • (1986) N Engl J Med , vol.315 , pp. 480-484
    • Adelroth, E.1    Morris, M.M.2    Hargreave, F.E.3    O'Byrne, P.M.4
  • 6
    • 0020618004 scopus 로고
    • Human airway monohydroxyeicosatetraenoic acid generation and mucus release
    • Marom Z, Shelhamer JH, Sun F, Kaliner M. Human airway monohydroxyeicosatetraenoic acid generation and mucus release. J Clin Invest 1983; 72: 122–7.
    • (1983) J Clin Invest , vol.72 , pp. 122-127
    • Marom, Z.1    Shelhamer, J.H.2    Sun, F.3    Kaliner, M.4
  • 7
    • 0019971503 scopus 로고
    • 4, increase the release of mucus from human airways in vitro
    • Marom Z, Shelhamer JH, Bach MK, Morton DR, Kaliner M. Slow-reacting substances, leukotrienes C4 and D4, increase the release of mucus from human airways in vitro. Am Rev Respir Dis 1982; 126: 449–51.
    • (1982) Am Rev Respir Dis , vol.126 , pp. 449-451
    • Marom, Z.1    Shelhamer, J.H.2    Bach, M.K.3    Morton, D.R.4    Kaliner, M.5
  • 8
    • 0021288729 scopus 로고
    • 4 production by the human alveolar macrophage: a potential mechanism for amplifying inflammation in the lung
    • Martin TR, Altman LC, Albert RK, Henderson WR. Leukotriene B4 production by the human alveolar macrophage: a potential mechanism for amplifying inflammation in the lung. Am Rev Respir Dis 1984; 129: 106–11.
    • (1984) Am Rev Respir Dis , vol.129 , pp. 106-111
    • Martin, T.R.1    Altman, L.C.2    Albert, R.K.3    Henderson, W.R.4
  • 9
    • 0019311062 scopus 로고
    • 4, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes
    • Ford-Hutchinson AW, Bray MA, Doig MV, Shipley ME, Smith MJH. Leukotriene B4, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes. Nature 1980; 286: 264–5.
    • (1980) Nature , vol.286 , pp. 264-265
    • Ford-Hutchinson, A.W.1    Bray, M.A.2    Doig, M.V.3    Shipley, M.E.4    Smith, M.J.H.5
  • 11
    • 0023927147 scopus 로고
    • Role of chemical mediators after antigen and exercise challenge in children with asthma
    • Iikura Y, Nagakura T, Walsh GM, et al. Role of chemical mediators after antigen and exercise challenge in children with asthma. J Allergy Clin Immunol 1988; 81: 1050–5.
    • (1988) J Allergy Clin Immunol , vol.81 , pp. 1050-1055
    • Iikura, Y.1    Nagakura, T.2    Walsh, G.M.3
  • 12
    • 0024477342 scopus 로고
    • 4 after antigen challenge and in acute asthma and allergic rhinitis
    • Taylor GW, Taylor I, Black P, et al. Urinary leukotriene E4 after antigen challenge and in acute asthma and allergic rhinitis. Lancet 1989; 1: 584–8.
    • (1989) Lancet , vol.1 , pp. 584-588
    • Taylor, G.W.1    Taylor, I.2    Black, P.3
  • 13
    • 0024474984 scopus 로고
    • 4, in bronchoalveolar lavage in bronchial asthma and other respiratory disease
    • Wardlaw AJ, Hay H, Cromwell O, Collins JV, Kay AB. Leukotrienes, LTC4 and LTB4, in bronchoalveolar lavage in bronchial asthma and other respiratory disease. J Allergy Clin Immunol 1989; 84: 19–26.
    • (1989) J Allergy Clin Immunol , vol.84 , pp. 19-26
    • Wardlaw, A.J.1    Hay, H.2    Cromwell, O.3    Collins, J.V.4    Kay, A.B.5
  • 14
    • 0025279184 scopus 로고
    • Assessment of bronchoalveolar cell and mediator response to isocapnic hyperpnea in asthma
    • Pliss LB, Ingenito EP, Ingram RH Jr, Pichurko B. Assessment of bronchoalveolar cell and mediator response to isocapnic hyperpnea in asthma. Am Rev Respir Dis 1990; 142: 73–8.
    • (1990) Am Rev Respir Dis , vol.142 , pp. 73-78
    • Pliss, L.B.1    Ingenito, E.P.2    Ingram, R.H.3    Pichurko, B.4
  • 15
    • 0022387420 scopus 로고
    • A presumptive role for leukotrienes in obstructive airways diseases
    • Lewis RA. A presumptive role for leukotrienes in obstructive airways diseases. Chest 1985; 88: Suppl 2: 98S–102S.
    • (1985) Chest , vol.88 , pp. 98S-102S
    • Lewis, R.A.1
  • 16
    • 0023024261 scopus 로고
    • Effects of a thromboxane synthetase inhibitor (OKY-046) and a lipoxygenase inhibitor (AA-861) on bronchial responsiveness to acetylcholine in asthmatic subjects
    • Fujimura M, Sasaki F, Nakatsumi Y, et al. Effects of a thromboxane synthetase inhibitor (OKY-046) and a lipoxygenase inhibitor (AA-861) on bronchial responsiveness to acetylcholine in asthmatic subjects. Thorax 1986; 41: 955–9.
    • (1986) Thorax , vol.41 , pp. 955-959
    • Fujimura, M.1    Sasaki, F.2    Nakatsumi, Y.3
  • 17
    • 0023269394 scopus 로고
    • Oral nafazatrom in man: effect on inhaled antigen challenge
    • Fuller RW, Maltby N, Richmond R, et al. Oral nafazatrom in man: effect on inhaled antigen challenge. Br J Clin Pharmacol 1987; 23: 677–81.
    • (1987) Br J Clin Pharmacol , vol.23 , pp. 677-681
    • Fuller, R.W.1    Maltby, N.2    Richmond, R.3
  • 18
    • 0022548106 scopus 로고
    • Effect of inhaled piriprost (U-60, 257) a novel leukotriene inhibitor, on allergen and exercise induced bronchoconstriction in asthma
    • Mann JS, Robinson C, Sheridan AQ, Clement P, Bach MK, Holgate ST. Effect of inhaled piriprost (U-60, 257) a novel leukotriene inhibitor, on allergen and exercise induced bronchoconstriction in asthma. Thorax 1986; 41: 746–52.
    • (1986) Thorax , vol.41 , pp. 746-752
    • Mann, J.S.1    Robinson, C.2    Sheridan, A.Q.3    Clement, P.4    Bach, M.K.5    Holgate, S.T.6
  • 19
    • 5244227745 scopus 로고
    • Propertiesof A-64077, a new potent orally active 5-lipoxygenase inhibitor
    • In: Zor U, Naor Z, Danon A, eds., of New trends in lipid mediators research. Basel, Switzerland: Karger
    • Carter GW, Young PR, Albert D, et al. Propertiesof A-64077, a new potent orally active 5-lipoxygenase inhibitor. In: Zor U, Naor Z, Danon A, eds. Leukotrienes and prostanoids in health and disease. Vol. 3 of New trends in lipid mediators research. Basel, Switzerland: Karger, 1989:50–5.
    • (1989) Leukotrienes and prostanoids in health and disease , vol.3 , pp. 50-55
    • Carter, G.W.1    Young, P.R.2    Albert, D.3
  • 20
    • 0023567409 scopus 로고
    • Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma
    • Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. Am Rev Respir Dis 1987; 136: 225–44.
    • (1987) Am Rev Respir Dis , vol.136 , pp. 225-244
  • 21
    • 0024434799 scopus 로고
    • Effect of a leukotriene antagonist, LY171883, on cold air-induced bronchoconstriction in asthmatics
    • Israel E, Juniper EF, Callaghan J, et al. Effect of a leukotriene antagonist, LY171883, on cold air-induced bronchoconstriction in asthmatics. Am Rev Respir Dis 1989; 140: 1348–53.
    • (1989) Am Rev Respir Dis , vol.140 , pp. 1348-1353
    • Israel, E.1    Juniper, E.F.2    Callaghan, J.3
  • 22
    • 0018380920 scopus 로고
    • Hyperpnea and heat flux: initial reaction sequence in exercise-induced asthma
    • Deal EC Jr, McFadden ER Jr, Ingram RH Jr, Jaeger JJ. Hyperpnea and heat flux: initial reaction sequence in exercise-induced asthma. J Appl Physiol 1979; 46: 476–83.
    • (1979) J Appl Physiol , vol.46 , pp. 476-483
    • Deal, E.C.1    McFadden, E.R.2    Ingram, R.H.3    Jaeger, J.J.4
  • 23
    • 0023235096 scopus 로고
    • Criticall considerations in the development of an assay for sulfidopeptide leukotrienes in plasma
    • Heavey DJ, Soberman RJ, Lewis RA, Spur B, Austen KF. Criticall considerations in the development of an assay for sulfidopeptide leukotrienes in plasma. Prostaglandins 1987; 33: 693–708.
    • (1987) Prostaglandins , vol.33 , pp. 693-708
    • Heavey, D.J.1    Soberman, R.J.2    Lewis, R.A.3    Spur, B.4    Austen, K.F.5
  • 24
    • 0001465756 scopus 로고
    • Leukotriene C: a slow reacting substance from murine mastocytoma cells
    • Murphy RC, Hammarstrom S, Samuelsson B. Leukotriene C: a slow reacting substance from murine mastocytoma cells. Proc Natl Acad Sci U S A 1979; 76: 4275–
    • (1979) Proc Natl Acad Sci U S A , vol.76 , pp. 4275
    • Murphy, R.C.1    Hammarstrom, S.2    Samuelsson, B.3
  • 26
    • 0020608744 scopus 로고
    • Bronchoconstriction stimulated by airway cooling: better protection with combined inhalation of terbutaline sulphate and cromolyn sodium than with either alone
    • Latimer KM, O'Byrne P, Morris MM, Roberts R, Hargreave FE. Bronchoconstriction stimulated by airway cooling: better protection with combined inhalation of terbutaline sulphate and cromolyn sodium than with either alone. Am Rev Respir Dis 1983; 128: 440–3.
    • (1983) Am Rev Respir Dis , vol.128 , pp. 440-443
    • Latimer, K.M.1    O'Byrne, P.2    Morris, M.M.3    Roberts, R.4    Hargreave, F.E.5
  • 27
    • 0020638329 scopus 로고
    • The protective effect of inhaled chlorpheniramine and atropine on bronchoconstriction induced by airway cooling
    • O'Byrne PM, Thomson NC, Morris M, Roberts RS, Daniel EE, Hargreave FE. The protective effect of inhaled chlorpheniramine and atropine on bronchoconstriction induced by airway cooling. Am Rev Respir Dis 1983; 128: 611–7.
    • (1983) Am Rev Respir Dis , vol.128 , pp. 611-617
    • O'Byrne, P.M.1    Thomson, N.C.2    Morris, M.3    Roberts, R.S.4    Daniel, E.E.5    Hargreave, F.E.6
  • 28
    • 0023948892 scopus 로고
    • Theophylline minimally inhibits bronchoconstriction induced by dry cold air inhalation in asthmatic subjects
    • Merland N, Cartier A, L'Archeveque J, Ghezzo H, Malo JL. Theophylline minimally inhibits bronchoconstriction induced by dry cold air inhalation in asthmatic subjects. Am Rev Respir Dis 1988; 137: 1304–8.
    • (1988) Am Rev Respir Dis , vol.137 , pp. 1304-1308
    • Merland, N.1    Cartier, A.2    L'Archeveque, J.3    Ghezzo, H.4    Malo, J.L.5
  • 29
    • 85023705634 scopus 로고
    • Inhibition of antigen-induced contractions of guinea-pig tracheal strips (GPTS) by lipoxygenase (5-LO) inhibitors
    • abstract
    • Malo PE, Wiley YD, Shaughnessy TK, et al. Inhibition of antigen-induced contractions of guinea-pig tracheal strips (GPTS) by lipoxygenase (5-LO) inhibitors. Am Rev Respir Dis 1989; 139: Suppl: A92. abstract.
    • (1989) Am Rev Respir Dis , vol.139 , pp. A92
    • Malo, P.E.1    Wiley, Y.D.2    Shaughnessy, T.K.3
  • 30
    • 0023729037 scopus 로고
    • Comparative contractile responses to sulfidopeptide leukotrienes in normal and asthmatic human subjects
    • Drazen JM. Comparative contractile responses to sulfidopeptide leukotrienes in normal and asthmatic human subjects. Ann N Y Acad Sci 1988; 524: 289–97.
    • (1988) Ann N Y Acad Sci , vol.524 , pp. 289-297
    • Drazen, J.M.1
  • 31
    • 0020695783 scopus 로고
    • Respiratory heat and water exchange: physiological and clinical implications
    • McFadden ER Jr. Respiratory heat and water exchange: physiological and clinical implications. J Appl Physiol 1983; 54: 331–61.
    • (1983) J Appl Physiol , vol.54 , pp. 331-361
    • McFadden, E.R.1
  • 32
    • 0021676105 scopus 로고
    • A reinterpretation of the effect of temperature and water content of the inspired air in exercise-induced asthma
    • Hahn A, Anderson SD, Morton AR, Black JL, Fitch KD. A reinterpretation of the effect of temperature and water content of the inspired air in exercise-induced asthma. Am Rev Respir Dis 1984; 130: 575–9.
    • (1984) Am Rev Respir Dis , vol.130 , pp. 575-579
    • Hahn, A.1    Anderson, S.D.2    Morton, A.R.3    Black, J.L.4    Fitch, K.D.5
  • 33
    • 0022508630 scopus 로고
    • Postexertional airway rewarming and thermally induced asthma: new insights into pathophysiology and possible pathogenesis
    • McFadden ER Jr, Lenner KA, Strohl KP. Postexertional airway rewarming and thermally induced asthma: new insights into pathophysiology and possible pathogenesis. J Clin Invest 1986; 78: 18–25.
    • (1986) J Clin Invest , vol.78 , pp. 18-25
    • McFadden, E.R.1    Lenner, K.A.2    Strohl, K.P.3


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