Induction of heat shock (stress) genes in the mammalian brain by hyperthermia and other traumatic events: A current perspective

Journal of Neuroscience Research

Volumn 27, Issue 3, 1990, Pages 247-255

  Brown, I R ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

CNS injury; Heat shock protein; hsp70; hyperthermia; immunocytochemistry; in situ hybridization; metabolic stress; stress protein

Indexed keywords

HEAT SHOCK PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; CENTRAL NERVOUS SYSTEM; HYPERTHERMIA; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; NERVE INJURY; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY; STRESS;

ANIMAL; BRAIN CHEMISTRY; BRAIN INJURIES; BRAIN ISCHEMIA; FEVER; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; HUMAN; INFECTION; KAINIC ACID; MAMMALS; MULTIGENE FAMILY; NERVE TISSUE PROTEINS; RABBITS; RATS; SEIZURES; SUPPORT, NON-U.S. GOV'T;

EID: 0025611307     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.490270302     Document Type: Review

References (110)

1. Coated vesicles and synaptogenesis: A developmental study in the cerebellar cortex of the rat
2. The induction of gene activity in Drosophila by heat shock
3. Hyperthermia protects against light damage in the rat retina
4. Age‐related expression of HSP‐70 mRNA in brain of heat stressed rats
5. Hyperthermia induces the synthesis of a heat shock protein by polysomes isolated from the fetal and neonatal mammalian brain
6. Effect of hyperthermia and LSD on gene expression in the mammalian brain and other organs
7. Modification of gene expression in the mammalian brain after hyperthermia
8. Analysis of protein synthesis in the mammalian brain using LSD and hyperthermia as experimental probes
9. Expression of a heat shock gene in fetal and maternal rabbit brain
10. Expression of heat shock genes (hsp70) in the mammalian brain: Distinguishing constitutively expressed and hyperthermia‐inducible species
11. Induction of a heat shock gene at the site of tissue injury in the rat brain
12. Uncoating ATPase is a member of the 70 kilodalton family of stress proteins
13. 70K heat shock related proteins stimulate protein translocation into microsomes
14. Protein synthesis in the mammalian retina following the intravenous administration of LSD
15. Induction of a heat shock protein in the isolated mammalian retina
16. A retinal heat shock protein is associated with elements of the cytoskeleton and binds to calmodulin
17. Altered expression of a heat shock protein in the mammalian nervous system in the presence of agents which affect microtubule stability
18. Heat shock protein in the mammalian brain and other organs following a physiologically relevant increase in body temperature induced by LSD
19. Effect of intravenous administration of d‐lysergic acid diethylamide on initiation of protein synthesis in a cell‐free system derived from brain
20. Effect of intravenous administration of d‐lysergic acid diethylamide on subsequent protein synthesis in a cell‐free system derived from brain
21. The heat shock response
22. Essential roles of 70 kDa heat inducible proteins
23. Trauma‐induced protein in rat tissues: A physiological role for a “heat shock” protein?
24. The role of stress proteins in membrane biogenesis
25. A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides
26. Axonal transport of a clathrin uncoating ATPase (HSC70): A role for HSC70 in the modulation of coated vesicle assembly in vivo
27. Synthesis of heat shock proteins in rat brain cortex after transient ischemia
28. Synthesis of the major inducible heat shock protein in rat hippocampus after neonatal hypoxia‐ischemia
29. Proteins as molecular chaperones
30. Hypoxia‐ischemia induces heat shock protein‐like (HSP72) immunoreactivity in neonatal rat brain
31. Characterization of a translational inhibitor isolated from rabbit brain following intravenous administration of d‐lysergic acid diethylamide
32. Effects on in vitro brain protein synthesis of a translational inhibitor isolated from rabbit brain following intravenous administration of LSD
33. Peptide binding and release by proteins implicated as catalysts of protein assembly
34. Selective effects of LSD and hyperthermia on the synthesis of synaptic proteins and glycoproteins
35. Heat shock proteins as markers of neural injury
36. Spinal cord injury and the stress protein, response
37. Comparison of labelled heat shock proteins in neuronal and non‐neuronal cells of Aplysia californica
38. Dissociation of clathrin from coated vesicles by the uncoating ATPase
39. Remodelling of neuronal membranes as an early response to deafferentation
40. Protein sorting to mitochondria: Evolutionary conservations of folding and assembly
41. Selective release from cultured mammalian cells of heat‐shock (stress) proteins that resemble glia–axon transfer proteins
42. Selective gene expression in focal cerebral ischemia
43. Competitive inhibition of hsp70 gene expression causes thermosensitivity
44. Protein synthesis in postischemic rat brain: A two dimensional electrophoretic analysis
45. Evidence for the participation of actin rnicrofilaments and bristle coats in the internalizing of gap junction membrane.
46. The relationship of the rat brain 68kDA microtubule‐associated protein with synaptosomal plasma membranes and with the Drosophila70kDa heatshock protein
47. The heat‐shock response
48. The heat shock proteins
49. The pattern of 72kd heat shock protein‐like immunoreactivity in the rat brain following generalized status epilepticus
50. Time course of induction of a heat shock gene (hsp70) in the rabbit cerebellum after LSD in vivo: Involvement of drug‐induced hyperthermia
51. 70‐Kilodalton heat shock protein induction in cerebellar astrocytes and cerebellar granule cells in vitro: Comparison with immunocytochemical localization after hyperthermia in vivo
52. Cellular localization of heat shock gene expression in rabbit cerebellum by in situ hybridization with plastic‐embedded tissue
53. Age‐related declines in anatomical plasticity and axonal sprouting
54. The family of heat shock protein 70 mRNAs are differentially induced in rat cerebellum, cortex, and non‐neuronal tissues
55. The major heat‐shock protein (hsp70) gene family: Related sequences in mouse, Drosophila and yeast
56. Ubiquitin and heat shock proteins in cultured nervous tissue after different stress conditions
57. In situ quantitation of heat shock 70 mRNAs in rat cerebellum after amphetamine‐induced hyperthermia
58. Induction of heat shock protein 70 mRNA in adult hamster facial nuclear groups following axotomy of the facial nerve
59. Induction of the 68/72 kDa heat‐shock protein during hydrogen peroxide toxicity
60. Induction of the major inducible 68‐kDa heat‐shock protein after rapid changes of extracellular pH in cultured rat astrocytes
61. The induction of the major heat‐stress protein in purified rat glial cells
62. Synthesis of a stress protein following transient ischemia in the gerbil
63. Effects of amphetamine on protein synthesis and energy metabolism in mouse brain: Role of drug‐induced hyperthermia
64. Heat shock response in gerbil brain after ischemia—In situ hybridization analysis
65. Heat shock RNA levels in brain and other tissues after hyperthermia and transient ischemia
66. Changes in chromatin and the phosphorylation of nuclear proteins during heat shock of Achlya ambisexualis
67. Speculations on the functions of the major heat shock and glucose‐regulated proteins
68. Heat shock proteins: Coming in from the cold
69. Heat shock and the sorting of luminal proteins
70. A possible mechanism for the resorption of attachment plates in the growing rat brain
71. Morphological changes in the neuritic growth cone and target neuron during synaptic junction development in culture
72. Heat shock is lethal to fibroblasts microinjected with antibodies against hsp 70
73. Enzymatic recycling of clathrin from coated vesicles
74. Heat shock proteins: the search for functions
75. An enzyme that removes clathrin coats: Purification of an uncoating ATPase
76. Cell damage in the brain: A speculative synthesis
77. Selective induction of a heat shock gene in fibre tracts and cerebellar neurons of the rabbit brain detected by in situ hybridization
78. Early stages of synaptogenesis in the cervical spinal cord of the chick embryo
79. Members of the 70‐kilodalton heat shock protein family contain a highly conserved calmodulin‐binding domain
80. Heat stress induces changes in protein synthesis and fast axonal transport in bullfrog sensory neurons
81. Heat stress increases delivery of a unique sub‐population of proteins conveyed by fast axonal transport
82. Stress protein systems of mammalian cells
83. Molecular and cellular effects of heat shock and related treatments of mammalian tissue culture cells
84. Functional aspects of the mammalian heat‐stress protein response
85. Synthesis and axonal transport of heat shock proteins
86. Photoreceptor protection from light damage by hyperthermia
87. Localization of retinal heat shock (stress) protein and mRNA induced by hyperthermia
88. Heat shock‐like protein is transferred from glial to axon
89. Stereotaxic injection of kainic acid into the striatum of rats induces synthesis of mRNA for heat shock protein 70
90. The 70‐kDa mammalian heat shock proteins are structurally and functionally related to the uncoating protein that releases clathrin triskelia from coated vesicles
91. Induction of stress protein hsp70 in nerve cells after status epilepticus in the rat
92. Localization of 70 kDa stress protein induction in gerbil brain after ischemia
93. Heat shock and thermotolerance during early rat embryo development
94. Regulation of the inducible heat‐shock 71 genes in early neural development of cultured rat embryos
95. Complex regulation of heat shock–and glucose‐responsive genes in human cells
96. The mammalian stress response: cell physiology and biochemistry of stress proteins
97. Purification of the major mammalian heat shock proteins
98. Structure and function of mammalian stress proteins
99. Cellular and biochemical events in mammalian cells during and after recovery from physiological stress
100. The brain 68‐kilodalton microtubule‐associated protein is a cognate form of the 70‐kilodalton mammalian heat‐shock protein and is present as a specific isoform in synaptosomal membranes
101. Stress proteins, arthritis, and autoimmunity
102. Structure and expression of the human gene encoding major heat shock protein HSP70
103. RNA splicing is interrupted by heat shock and is rescued by heat shock protein synthesis
104. Translation of unspliced transcripts after heat shock
105. Stress proteins and immunology
106. Stress proteins, infection, and immune surveillance