The Importance of α‐Adrenergic Stimulation of Cardiac Tissue and its Contribution to Arrhythmogenesis During Ischemia

Journal of Cardiovascular Electrophysiology

Volumn 1, Issue 6, 1990, Pages 529-542

  PRIORI, SILVIA G ^a   CORR, PETER B ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 [2 (4 HYDROXYPHENYL)ETHYLAMINOMETHYL]TETRALONE; 2 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 4,4 DIMETHYL 1,3(2H,4H) ISOQUINOLINEDIONE; 2 [[2 (2,6 DIMETHOXYPHENOXY)ETHYL]AMINOMETHYL] 1,4 BENZODIOXAN; ADRENERGIC RECEPTOR; CHLOROETHYLCLONIDINE; NADOLOL; OXYMETAZOLINE; PHENTOLAMINE; PHENYLEPHRINE; PRAZOSIN;

ANIMAL TISSUE; DOG; HEART MUSCLE ISCHEMIA; HEART RATE; NONHUMAN; REVIEW;

EID: 0025609772     PISSN: 10453873     EISSN: 15408167     Source Type: Journal    
DOI: 10.1111/j.1540-8167.1990.tb01087.x     Document Type: Review

References (75)

1. 1‐adrenoceptor density in the rai left ventricle
2. + currents in rat ventricular myocytes
3. Anti‐arrhythmic effects of prazosin and propranolol during coronary artery occlusion and reperfusion in dogs and pigs
4. Inositol trisphosphate, a novel second messenger in cellular signal transduction
5. Inositol trisphosphate and diacylglycerol: two interacting second messengers
6. 1‐adrenoceptors in the mammalian heart
7. 1 ‐adrenergic stimulation in FRTL5 thyroid cells
8. In creased α‐adrenergic receptors in ischemic cat myocardium: A potential mediator of electrophysiological derangements
9. Amphipathic metabolites and membrane dysfunction in ischemic myocardium
10. Prophylaxis of early ventricular fibrillation by inhibition of acylcarnitine accumulation
11. 1‐adrenergic receptor
12. Amphipathic lipid metabolites and arrhythmias during myocardial ischemia
13. Arrhythmogenic and electrophysiological effects of alpha adrenoceptor stimulation during myocardial ischaemia and reperfusion
14. Relevant features of the pharmacology of prazosin
15. Alpha, adrenocep‐tors in the ischaemic and reperfused myocardium
16. The multiple membrane spanning topography of the β‐adrenergic receptor: Localization of the sites of binding, glycosylation and regulatory phosphorylation by limited proteolysis
17. Differentiation by cholinergic stimulation of positive inotropic actions mediated via α‐ and β‐adrenoceptors in the rabbit heart
18. Regulation of myocardial contractility via adrenoceptors: differential mechanisms of α‐ and β‐adrenoceptor‐mediated actions
19. 2+ mediated through α‐ and β‐adrenoceptors
20. Molecular mechanisms involved in α‐adrenergic responses
21. Mechanisms involved in alpha‐adrenergic phenomena
22. 1‐adrenoceptors
23. Modulation of canine myocardial sarcolemmal membrane fluidity by amphiphilic compounds
24. α‐Adrenergic receptor stimulation during simulated ischemia and reperfusion in canine cardiac Purkinje fibers
25. Nonuniform recovery of excitability in ventricular muscle
26. Effect on α‐ and β‐sympathomimetic agonists on calcium‐dependent slow action potential and force of contraction in the rabbit papillary muscle
27. 1‐adrenergic receptors on adult canine myocytes
28. 1‐adrenergic stimulation in adult cardiac mytxytes
29. The contribution of α‐ and β‐adrenergic mechanisms in the genesis of arrhythmias during myocardial ischemia and reperfusion
30. Sympathetic stimulation selectively increases inositol trisphosphate levels in ischemic myocardium in vivo
31. Anion exchange chromatographic separation of inositol phosphates and their quantification by gas chromatography
32. 1‐adrenergic stimulation in hypoxic cardiac myocytes
33. 2‐adrenergic receptor metabolism in a muscle cell line, BC3H1
34. Coen‐zyme A and carnitine distribution in normal and ischemic heart
35. Results of sympathetic dener‐vation in the canine heart: Supersensitivity that may be arrhythmogenic
36. Flow of “injury” current and patterns of excitation during early ventricular arrhythmias in acute regional myocardial ischemia in isolated porcine and canine hearts. Evidence for 2 different arrhythmogenic mechanisms
37. An investigation into the characteristics of repjerfusion‐induced arrhythmias in the anesthetized ral and their susceptibility to antiarrhythmic agents
38. The dependence of electrophysiological derangements on accumulation of endogenous long‐chain acylcarnitine in hypoxic neonatal rat myocytes
39. 2‐adrenergic receptor
40. Molecular biology of adrenergic receptors
41. Externalization of α‐adrenergic receptors promoted by myocardial ischemia
42. Ischemia‐ and agonist‐induced changes in α‐ and β‐adrenergic receptor traffic in guinea pig heart
43. Sympathetic neural modulation of cardiac impulse initiation and repolarization in the newborn rat
44. 2+
45. Beta‐adrenergic and muscarinic cbolinergic receptors on canine myocardium: Effects of ischemia
46. I‐adrenergic receptors
47. Relationship between beta‐adrenergic receptor numbers and physiological responses during experimental canine myocardial ischemia
48. 1‐Adrenoceptor‐mediated phosphoinositide breakdown and inotropic response in rat left ventricular papillary muscles
49. Reentrant and nonreentrant mechanisms contribute to arrhythmogenesis during early myocardial ischemia: Results using three‐dimensional mapping
50. Delayed afterdepolarizations elicited in vivo by left stellate ganglion stimulation
51. α‐Adrenergic induced delayed afterdepolarizations in hypoxic isolated ventricular canine myocytes
52. Mechanisms underlying early and delayed afterdepolarizations induced by catecholamines
53. Developmental changes in alpha adrenergic effects on canine Purkinje fiber automaticity
54. 2‐adrenergic receptor subtype
55. The regulation of the calcium conductance of cardiac muscle by adrenaline
56. Effects of adrenergic amines on electrophysiologic properties and automaticity of neonatal and adult canine cardiac Purkinje fibers
57. The time course of the effects of beta‐ and alpha‐adrenoceptor stimulation by isoprenaline and methoxamine on the contractile force and cAMP level of the isolated rabbit papillary muscle
58. The effect of antiarrhythmic drugs on life‐threatening arrhythmias induced by the interaction between acute myocardial ischemia and sympathetic hyperactivity
59. k via a pertussis toxin‐sensitive pathway
60. Alpha‐adrenergic mediated accumulation of calcium in reperfused myocardium
61. α‐Adrenergic contributions lo dysrhythmia during myocardial ischemia and reperfusion in cats
62. Changes in tissue levels of carnitine and other metabolites during myocardial ischemia and anoxia
63. Elcctrophysiologic and antiarrhythmic effects of phentolamine in experimental coronary artery occlu‐sion and reperfusion in the dog
64. 1‐Adrenergic receplor‐ l inked guanine nucleotide‐binding protein in muscle and kidney epithelial ceils
65. The effect of alpha‐and beta‐adrcnoceptor antagonist agents on reperfusion ventricular fibrillation and metabolic status in the isolated perfused rat heart
66. 2 cells
67. Inhibitory effect mediated by a|‐adrcnoceptors on transient outward current in isolated rat ventricular cells
68. Cyclic AMP and contractile activity in heart
69. 1‐adrenergic receptors on sarcolem‐ma from normal subjects and patients with idiopathic dilated cardiomyopathy: Characteristics and linkage to GTP‐binding protein
70. Phospholipase C modulates automaticity of canine cardiac Purkinje fibers
71. Kinetics of smooth and skeletal muscle activation by laser pulse photolysis of caged inositol 1,4,5‐trisphosphate
72. 1‐adrenoceptor blockade with prazosin
73. Prevention of reperfusion dysrhythmias by selective coronary alpha‐adrenergic blockade
74. Effects of α‐adrenergic stimulation on intracellular sodium activity and automaticity in canine Purkinje fibers