Use of live attenuated bacteria to stimulate immunity

Research in Microbiology

Volumn 141, Issue 7-8, 1990, Pages 769-773

  Fairweather, N F ^a   Chatfield, S N ^a   Charles, I G ^a   Roberts, M ^a   Lipscombe, M ^a   Jing Li, L ^a   Strugnell, D ^a   Comerford, S ^a   Tite, J ^a   Dougan, G ^a  

^a Department of Molecular Biology ^*  (United Kingdom)

Author keywords

Immunity, Antigen, Live bacteria; Salmonella, Oral vaccine, Attenuation

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGENICITY; ATTENUATION; BORDETELLA PERTUSSIS; CONFERENCE PAPER; IMMUNIZATION; MOUSE; MUCOSA; NONHUMAN; PRIORITY JOURNAL; SALMONELLA; YERSINIA ENTEROCOLITICA;

ANIMAL; ANTIGENS, BACTERIAL; BACTERIAL VACCINES; MICE; MUCOUS MEMBRANE; SALMONELLA; VACCINES, ATTENUATED; VACCINES, SYNTHETIC;

ANIMALIA; BORDETELLA PERTUSSIS; SALMONELLA; YERSINIA ENTEROCOLITICA;

EID: 0025608644     PISSN: 09232508     EISSN: 17697123     Source Type: Journal    
DOI: 10.1016/0923-2508(90)90109-4     Document Type: Article

References (17)

1. Virulence, persistence, and immunogenicity of Yersinia enterocolitica 0:8 aroA mutants
2. Molecular cloning and characterization of protective outer membrane protein P.69 from Bordetella pertussis
3. Oral administration of a streptococcal antigen coupled to cholera toxin B subunit evokes strong antibody responses in salivary glands and extramucosal tissues
4. Cistrons encoding Escherichia coli heat-labile toxin
5. Characterization of porin and ompR mutants of a virulent strain of Salmonella typhimurium: ompR mutants are attenuated in vivo
6. Construction and characterization of vaccine strains of Salmonella harboring mutations in two different aro genes
7. Oral vaccination of mice against tetanus by use of a live attenuated Salmonella carrier
8. Structure of tetanus toxin.-I. Breakdown of the toxin molecule and discrimination between polypeptide fragments
9. Action of cholera toxin and the prevention and treatment of cholera
10. Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live oral vaccines
11. Cloning and nucleotide sequence of the aroA gene of Bordetella pertussis
12. Isolation of orally attenuated Salmonella typhimurium following TnphoA mutagenesis
13. Immune response to cholera toxin epitope inserted in Salmonella flagellin
14. Cloning and characterization of the serC and aroA genes of Yersinia enterocolitica, and construction of an aroA mutant
15. Protective immunity evoked by oral administration af attenuated aroA Salmonella typhimurium expressing cloned streptococcal M protein
16. Construction and characterization in vivo of Bordetella pertussis aroA mutants
17. Stable expression of foreign antigens from the chromosome of Salmonella typhimurium vaccine strains