A Single Cholesterol Measurement Underestimates the Risk of Coronary Heart Disease: An Empirical Example From the Lipid Research Clinics Mortality Follow-up Study

JAMA: The Journal of the American Medical Association

Volumn 264, Issue 23, 1990, Pages 3044-3046

  Davis, C E ^a   Rifkind, Basil M ^b   Brenner, Hermann ^c   Gordon, David J ^b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c UNIVERSITY OF ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; LIPID;

ADULT; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CHOLESTEROL BLOOD LEVEL; CORONARY ARTERY DISEASE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; RISK FACTOR;

ADULT; CEREBROVASCULAR DISORDERS; CHOLESTEROL; CORONARY DISEASE; FEMALE; FOLLOW-UP STUDIES; HUMAN; MALE; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RISK FACTORS; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0025605695     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.1990.03450230080033     Document Type: Article

References (13)

1. Kannel WB, Gordon T. Some characteristics related to the incidence of cardiovascular disease and death: 18 years’ follow-up (section 30). In: The Framingham Study: An Epidemiologic Investigation of Cardiovascular Disease. Washington, DC: US Dept of Health, Education, and Welfare; 1974. NIH publication 74-599.
2. Prentice RL. Covariate measurement errors and parameter estimation in a failure time regression model. Biometrika. 1982;69:331-332.
3. Kupper LL. Effects of the use of unreliable surrogate variables on the validity of epidemiologic research studies. Am J Epidemiol. 1984;120: 643-648.
4. Fuller WA. Measurement Error Models. New York, NY: John Wiley & Sons Inc; 1987.
5. McMahon S, Peto R, Cutler J, et al. Blood pressure, stroke, and coronary heart disease, I: prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias. Lancet. 1990;335:765-774.
6. Gordon DJ, Ekelund LG, Karon JM, et al. Predictive value of the exercise tolerance test for mortality in North American men: the Lipid Research Clinics Mortality Follow-up Study. Circulation. 1986;74:252-261.
7. Central Patient Registry and Coordinating Center for the Lipid Research Clinics. Reference Manual for the Lipid Research Clinics Program Prevalence Study, I and II. Chapel Hill, NC: Department of Biostatistics, University of North Carolina at Chapel Hill; February 1974.
8. Manual of Operations, Lipid Research Clinics Program, I: Lipid and Lipoprotein Analysis. Bethesda, Md: National Heart, Lung and Blood Institute, National Institutes of Health; 1974. US Dept of Health, Education, and Welfare publication NIH 75-628.
9. Laboratory Methods Committee of the Lipid Research Clinics Program. Cholesterol and triglyceride concentrations in serum/plasma pairs. Clin Chem. 1977;23:60-63.
10. Cox DR. Regression models and life tables (with discussion). J R Stat Soc. 1972;B34:187-220.
11. Martin MJ, Hulley SB, Browner WS, Kuller KH, Wentworth D. Serum cholesterol, blood pressure, and mortality: implications from a cohort of 361662 men. Lancet. 1986;2:933-936.
12. Lipid Research Clinics Program. The Lipid Research Clinics Coronary Primary Prevention Trial results, I: reduction in the incidence of coronary heart disease. JAMA. 1984;251:351-364.
13. Miettinen OS. Proportion of disease caused or prevented by a given exposure, trait, or intervention. Am J Epidemiol. 1974;99:325-332.