A study of the efficacy of the bradykinin antagonist, NPC 567, in rhinovirus infections in human volunteers

Antiviral Research

Volumn 14, Issue 6, 1990, Pages 339-344

  Higgins, P G ^a   Barrow, G I ^a   Tyrrell, D A J ^a  

^a Harvard Hospital   (United Kingdom)

Author keywords

Bradykinin antagonist (NPC 567); Human volunteer; Rhinovirus

Indexed keywords

BRADYKININ DERIVATIVE; DEXTRO ARGINYLBRADYKININ[3 HYDROXYPROLINE 7 DEXTRO PHENYLALANINE];

ADULT; ARTICLE; COMMON COLD; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HUMAN; HUMAN EXPERIMENT; INTRANASAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RHINOVIRUS;

ADULT; BRADYKININ; COMMON COLD; DOUBLE-BLIND METHOD; FEMALE; HUMAN; MALE; PICORNAVIRIDAE INFECTIONS; RHINOVIRUS;

RHINOVIRUS;

EID: 0025605576     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/0166-3542(90)90052-9     Document Type: Article

References (8)

1. Suppression of colds in human volunteers by a new synthetic drug (R61837)
2. The study of antiviral compounds in volunteers
3. Bradykinin receptor antagonists
4. Influence of atopy on the clinical manifestations of coronavirus infection in adult volunteers
5. Mediators of immediate hypersensitivity in nasal secretions during natural colds and rhinovirus infections
6. Kinins are generated during experimental rhinovirus colds
7. Kinins are general in nasal secretions during natural rhinovirus colds
8. Nasal provocation with bradykinin induces symptoms of rhinitis and a sore throat