Amniotic fluid interleukin 6 in preterm labor: Association with infection

Journal of Clinical Investigation

Volumn 85, Issue 5, 1990, Pages 1392-1400

  Romero, Roberto ^a   Avila, Cecilia ^a   Santhanam, Uma ^b   Sehgal, Pravinkumar B ^b  

^a YALE UNIVERSITY   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Bacterial endotoxins; Cytokines; Decidua; Parturition; Prematurity

Indexed keywords

CYTOKINE; ENDOTOXIN; INTERLEUKIN 6;

ADULT; AMNION FLUID; ARTICLE; CHILDBIRTH; FEMALE; HUMAN; MAJOR CLINICAL STUDY; NEWBORN; PREGNANCY; PREMATURITY; PRIORITY JOURNAL;

ADULT; AMNIOTIC FLUID; BACTERIA; DECIDUA; FEMALE; HUMAN; INTERLEUKIN-6; LABOR, PREMATURE; ORGAN CULTURE; PREGNANCY; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0025369863     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI114583     Document Type: Article

References (44)

1. van den Berg, B. J., and F. W. Oechsli. 1984. Prematurity. In Perinatal Epidemiology. M. Bracken, editor. Oxford University Press, London, UK. 69-85.
2. Romero, R., and M. Mazor. 1988. Infection and preterm labor. Clin. Obstet. Gynecol. 31:553-584.
3. Romero, R., R. Quintero, E. Oyarzun, Y. K. Wu, M. Mazor, V. Sabo. and J. C. Hobbins, 1988. Intraamniotic infection and the onset of labor in preterm rupture of membranes. Am. J. Obstet. Gynecol. 159:661-666.
4. Romero, R., M. Sirtori, E. Oyarzun, C. Avila, M. Mazor, R. Callahan, V. Sabo, A. Athanassiadis, and J. C. Hobbins. 1989. Prevalence, microbiology and clinical significance of intraamniotic infection in women with preterm labor and intact membranes. Am. J Obstet. Gynecol. 161:817-824.
5. Romero, R., D. T. Brody, Y. K. Wu, M. Mazor, E. Oyarzun, J. C. Hobbins, and S. Durum. 1989. Infection and labor. III. Interleukin-1 : a signal for the initiation of parturition. Am. J. Obstet. Gynecol. 160:1117-1123.
6. Romero, R., K. R. Manouge, M. D. Mitchell, Y. K. Wu, E. Oyarzun, J. C. Hobbins, and A. Cerami. 1989. Infection and labor. IV. Cachectin-tumor necrosis factor in the amniotic fluid of women with intraamniotic infection and preterm labor. Am. J. Obstet. Gynecol. 161:336-341.
7. 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte stimulating factor and regulates the major acute phase protein response in liver cells. Proc. Natl. Acad. Sci. USA. 84:7251-7255.
8. 2-interferon/B cell differentiation factor-2-hepatocyte stimulating factor by human fibroblastsand monocytes. J. Biol. Chem. 263:7760-7766.
9. 2-interferon/hepatocyte stimulating factor/interleukin-6. Biochem. Biophys. Res. Commun. 152:1144-1150.
10. 2/IL-6 in serum and body fluids during acute bacterial infection. J. Immunol. 143:948-953.
11. May, L. T., G. Torcia. F. Cozzolino, A. Ray, S. B. Tatter, U. Santhanam, P. B. Sehgal, and D. Stern. 1989. Interleukin-6 gene expression in human endothelial cells: RNA start sites, multiple IL-6 proteins and inhibition of proliferation. Biochem. Biophys. Res. Commun. 159:991-998.
12. 2 as a circulating hormone: induction by cytokine administration in man. J. Immunol. 142:1542-1547.
13. 2-IFN/ IL-6 in man. J. Immunol. 142:2321-2324.
14. 2-interferon gene. Proc. Nail. Acad. Sci. USA. 83:5219-5222.
15. 2/B cell stimulatory factor 2/hepatocyte stimulating factor gene to human chromosome 7p15-p21. Genomics. 2:203-208.
16. 2/B cell stimulating factor/interleukin-6" gene: DNA polymorphism studies and localization to chromosome 7p21. Genomics. 3:8-16.
17. 2-interferon by tumor necrosis factor: a heomeostatic mechanism in the control of cell proliferation. Cell. 45:659-666.
18. Kohase, M., L. T. May, I. Tamm, J. Vilček, and P. B. Sehgal. 1987. A cytokine network in human diploid fibroblasts: interactions of β interferons, tumor necrosis factor, platelet-derived growth factor and interleukin-1. Mol. Cell. Biol. 7:273-280.
19. 2-interferon/B cell differentiation factor BSF-2 gene expression in human fibroblasts by diacylglycerols and the calcium ionophore A23187. Proc. Nutl. Acad. Sci. USA. 84:3663-3667.
20. 2-interferon by human fibroblasts. J. Exp. Med. 166:1300-1307.
21. 2/B cell differentiation factor BSF-2/hepatocyte stimulating factor HSF gene in human fibroblasts by other cytokines. J. Immunol. 140:974-977.
22. 2-interferon/hepatocyte stimulating factor/interleukin-6" gene in virus-infected human fibroblasts. J. Exp. Med. 167:1951-1956.
23. 2/B cell stimulatory factor 2) in human fibroblasts is triggered by an increase in intracellular cyclic AMP. J. biol. Chem. 263:6177-6182.
24. 2-interferon/hepatocyte stimulating factor/interleukin-6" promoter by cytokines, viruses and second messengers. Proc. Natl. Acad. Sci. USA. 85:6701-6705.
25. Sehgal, P. B., G. Grieninger, and G. Tosato. 1989. Regulation of the acute phase and immune responses: interleukin-6. Ann. NY Acad. Sci. 557:1-583.
26. Kupper, T., K. Min, P. B. Sehgal, H. Mizutani, N. Birchall, A. Ray. and L. May. 1989. Production of IL-6 by keratinocytes: implications for epidermal inflammation and immunity. Ann. NY Acad. Sci. 557:454-465.
27. 2/interleukin-6 by freshly-explanted human endometrial stromal cells: modulation by estradiol-17β. J. Immunol. 142:3134-3139.
28. Evans, M. I., S. N. Hajj, L. D. Devoe, N. S. Angerman, and A. H. Moawad. 1980. C-reactive protein as a predictor of infectious morbidity with premature rupture of membranes. Am. J. Obstet. Gynecol. 138:628-652.
29. Hawrylyshyn, P., P. Bernstein, J. E. Milligan, S. Soldin, A. Pilard, B. Chir, and F. R. Papsin. 1983. Premature rupture of membranes: the role of C-reactive protein in the prediction of chorioamnionitis. Am. J. Obstet. Gynecol. 147:240-246.
30. Potkul, R. K., A. H. Moawad, and K. L. Ponto. 1985. The association of subclinical infection with preterm labor: the role of C-reactive protein. Am. J. Obstet. Gynecol. 153:642-645.
31. Dodds, W. G., and J. D. lams. 1987. Maternal C-reactive protein and preterm labor. J. Reprod. Med. 32:527-530.
32. Guzick, D. S., and K. Winn. 1985. The association of chorioamnionitis with preterm delivery. Obstet. Gynecol. 65:11-16.
33. Moshage, H. J., H. M. J. Roelofs, J. F. van Pelt, B. P. C. Hazenberg, M. A. van Leeuwen, P. C. Limburg, L. A. Aarden, and S. H. Yap. 1988. The effect of interleukin-1, interleukin-6 and its relationship on the synthesis of serum amyloid A and C-reactive protein in primary cultures of adult human hepatocytes. Biochem. Biophys. Res. Commun. 155:112-117.
34. Ganapathi, M. K., L. T. May, D. Schultz, A. Brabenec, J. Weinstein, P. B. Sehgal, and I. Kushner. 1988. Role of interleukin-6 in regulating synthesis of C-reactive protein and serum amyloid A in human hepatoma cell lines. Biochem. Biophys. Res. Commun. 157:271-277.
35. Caritis, S. N. 1988. A pharmacologic approach to the infusion of ritodrine. Am. J. Obstet. Gynecol. 158:380-384.
36. Romero, R., K. Scharf, M. Mazor, M. Emamian, J. Ryan, and J. C. Hobbins. 1988. The clinical value of gas liquid chromatography in the detection of intra-amniotic microbial invasion. Obstet. Gynecol. 72:44-50.
37. 2 (BSF-2, IL-6). Science (Wash. DC). 239:502-504.
38. 2/interleukin-6 is a costimulant for human T lymphocytes. J. Immunol. 141:1556-1562.
39. Kenney, J. S., M. P. Masada, E. M. Eugui, B. M. Delustro, M. A. Mulkins, and A. C. Allison. 1987. Monoclonal antibodies to human recombinant interleukin-1 (IL-1)β: quantitation of IL-1β and inhibition of biological activity. J. Immunol. 138:4236-4242.
40. Benedetti, T. J. 1983. Maternal complications of parenteral β-sympathomimetic therapy for premature labor. Am. J. Obstet. Gynecol. 145:1-6.
41. Grossman, R. M., J. Krueger, D. Yourish, A. Granelli-Piperno, D. P. Murphy, L. T. May. T. S. Kupper, P. B. Sehgal, and A. B. Gottlieb. 1989. Interleukin-6 (IL-6) is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes. Proc. Nail. Acad. Sci. USA. 86:6367-6371.
42. Philip, A. G. S. 1985. Response of C-reactive protein in neonatal group B streptococcal infection. Pediatr. Infect. Dis. J. 4:145-148.
43. Philip, A. G. S. 1979. The protective effect of acute phase response reactants in neonatal sepsis. Acta Paediatr. Scand. 68:481-483.
44. Romero, R., S. Durum, C. A. Dinarello, E. Oyarzun, J. C. Hobbins, and M. D. Mitchell. 1989. Interleukin-1 stimulates prostaglandin biosynthesis by human amnion. Proslaglandins. 37:13-22.