DNA intercalation and cleavage of an antitumor antibiotic dynemicin that contains anthracycline and enediyne cores

Proceedings of the National Academy of Sciences of the United States of America

Volumn 87, Issue 10, 1990, Pages 3831-3835

  Sugiura, Y ^a   Shiraki, T ^a   Konishi, M ^a   Oki, T ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

action mechanism; Hybrid antibiotic; minor groove; nucleotide specificity

Indexed keywords

DYNEMICIN A;

ARTICLE; DNA CLEAVAGE; DRUG DNA INTERACTION; INTERCALATION COMPLEX; PRIORITY JOURNAL;

ANTHRAQUINONES; ANTIBIOTICS, ANTINEOPLASTIC; BASE SEQUENCE; DNA; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; PLASMIDS; RESTRICTION MAPPING; SUPPORT, NON-U.S. GOV'T;

EID: 0025368037     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.87.10.3831     Document Type: Article

References (0)