Cell-oriented alternatives to dose, quality factor, and dose equivalent for low-level radiation

Health Physics

Volumn 59, Issue 1, 1990, Pages 35-48

  Sondhaus, C A ^a   Bond, V P ^b   Feinendegen, L E ^c  

^a U S ARMY   (United States)

^b BROOKHAVEN NATIONAL LABORATORY   (United States)

^c FORSCHUNGSZENTRUM JÜLICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL; CONFERENCE PAPER; CYTOLOGY; MICRODOSIMETRY; NONBIOLOGICAL MODEL; NONHUMAN; RADIATION DOSE; RADIATION DOSE EQUIVALENT; RADIATION RESPONSE;

CELLS; DOSE-RESPONSE RELATIONSHIP, RADIATION; MODELS, BIOLOGICAL; RADIATION DOSAGE; SUPPORT, U.S. GOV'T, NON-P.H.S.;

EID: 0025367395     PISSN: 00179078     EISSN: 15385159     Source Type: Journal    
DOI: 10.1097/00004032-199007000-00004     Document Type: Article

References (18)

1. Barendsen, G. W. Mechanism of action of different ionizing radiations on the proliferative capacity of mammalian cells. In: Cole, A., ed. Theoretical and experimental biophysics. New York: Marcel Dekker; 1967:168-231.
2. Bond, V. P. The conceptual basis for evaluating risk from low- level radiation exposure. In: Critical issues in setting radiation protection dose limits, Proceedings of a National Council on Radiation Protection and Measurements Conference. Be- thesda, MD: NCRP; NCRP Proceedings No. 3; 1982:25-62.
3. Bond, V. P.; Sondhaus, C. A. Common misinterpretations of the “linear, no-threshold” relationship used in radiation protection. Rad. Env. Biophys. 26:253-261; 1987.
4. Bond, V. P.; Feinendegen, L. E.; Booz, J. What is a “low dose” of radiation? Int. J. Rad. Biol. 53:1-12; 1988.
5. Bond, V. P.; Varma, M. N. Low-level radiation response explained in terms of fluence and cell critical volume dose. In: Eighth Symposium on Microdosimetry. Jttlich, West Germany: Commission of the European Communities; 1983: 423-439.
6. Bond, V. P.; Varma, M. N.; Sondhaus, C. A.; Feinendegen, L. E. An alternative to absorbed dose, quality, and RBE at low exposures. Rad. Res. 104(Suppl. 8):552-557; 1985.
7. Booz, J. Mapping of fast neutron radiation quality. In: Proceedings of the Third Symposium on Neutron Dosimetry in Biology and Medicine. Luxembourg: Commission of the Eu¬ropean Communities; Report No. EUR5848; 1978:499-514.
8. Booz, J.; Feinendegen, L. E. A microdosimetric understanding of low dose radiation effects. Int. J. Rad. Biol. 53:13-21; 1988.
9. Cox, R.; Thacker, J.; Goodhead, D. T.; Munson, R. J. Mutation and inactivation of mammalian cells by various ionizing radiations. Nature 267:425-427; 1977.
10. Feinendegen, L. E.; Booz, J. K.; Bond, V. P.; Sondhaus, C. A. Microdosimetric approach to the analysis of cell responses at low dose and low dose rate. Rad. Prot. Dosim. 13:299-306; 1985.
11. International Commission on Radiation Units and Measurements. Microdosimetry. Bethesda, MD: ICRU; ICRU Report 36; 1983.
12. International Commission on Radiation Units and Measurements. The quality factor in radiation protection. Bethesda, MD: ICRU; ICRU Report 40; 1986.
13. Morstin, K.; Bond, V. P.; Varma, M. N.; Baum, J. W. A probabilistic approach to relate microdosimetry, biological effects and radiation quality. Rad. Res. 120:383-402; 1989.
14. National Council on Radiation Protection and Measurements. Tritium and other radionuclide labeled organic compounds incorporated in genetic material. Bethesda, MD: NCRP; NCRP Report No. 63; 1979.
15. Rossi, H. H.; Rosenzweig, W. A device for the measurement of dose as a function of specific ionization. Radiology 64:404; 1955.
16. Skarsgard, L. D.; Kihlmann, B. A.; Parker, L.; Pujara, C. N.; Richardson, S. Survival, chromosome abnormalities and re-covery in heavy-ion- and x-irradiated cells. Rad. Res. 7:208-221; 1967.
17. Sparrow, A.; Underbrink, A. C.; Rossi, H. H. Mutations induced in Tradescantia by small doses of x rays and neutrons: Analysis of dose in response curves. Science 176:916-921; 1972.
18. Todd, P.; Wood, J. C. S.; Walker, J. T.; Weiss, S. J. Lethal, potentially lethal, and nonlethal damage induction by heavy ions in cultured human cells. Rad. Res. 104(suppl. 8):5-12; 1985