Enhanced binding of lupus sera to the polyamine‐induced left‐handed z‐dna form of polynucleotides

Arthritis & Rheumatism

Volumn 33, Issue 3, 1990, Pages 356-365

  Thomas, T J ^a,b   Meryhew, Nancy L ^a,b   Messner, Ronald P ^a,b  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; POLYAMINE; SPERMIDINE; SPERMINE;

ARTICLE; CLINICAL ARTICLE; HUMAN; METHODOLOGY; PRIORITY JOURNAL; SERUM; SYSTEMIC LUPUS ERYTHEMATOSUS;

AUTOANTIBODIES; DNA; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMAN; IMMUNOGLOBULIN G; LUPUS ERYTHEMATOSUS, SYSTEMIC; POLYAMINES; POLYNUCLEOTIDES; SPERMIDINE; SPERMINE; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0025349433     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.1780330308     Document Type: Article

References (38)

1. DNA sequence and conformation specificity of lupus autoantibodies: preferential binding to the left‐handed Z‐DNA form of synthetic polynucleotides.
2. Multiple serologic reactions and their relationship to clinical activity in systemic lupus erythematosus.
3. Autoantibodies to nuclear antigen (ANA): their immunobiology and medicine.
4. Origin of anti‐DNA autoantibodies.
5. Antibodies crossreactive with DNA and cardiolipin in patients with systemic lupus erythematosus.
6. Polyspecific monoclonal lupus autoantibodies reactive with both polynucleotides and phospholipids.
7. Z‐DNA specific antibodies in human systemic lupus erythematosus.
8. Left‐handed “Z” DNA antibodies in rheumatoid arthritis and systemic lupus erythematosus.
9. A new assay for anti‐DNA antibodies in serum which includes the measurement of anti‐ Z‐DNA.
10. Salt‐induced co‐operative conformational change of a synthetic DNA: equilibrium and kinetic studies with poly(dG‐dC).
11. Molecular structure of a left‐handed helical DNA fragment at atomic resolution.
12. 5DC).
13. Structural specificity of polyamines in left‐handed Z‐DNA formation: immunological and spectroscopic studies.
14. 8‐acetyl spermidines.
15. A left‐handed (Z) conformation of poly(dA‐dC) poly(dG‐dT) induced by polyamines.
16. Polyamines.
17. Recent advances in biochemistry of polyamines in eukaryotes.
18. Serum‐free polyamines in children with systemic lupus erythematosus.
19. Aggregation of DNA by analogs of spermidine: enzymatic and structural studies.
20. DNA condensation with polyamines. I. Spectroscopic studies.
21. Collapse of DNA by trivalent cations: pH and ionic specificity effects.
22. Ionic and structural effects on the thermal helix‐coil transition of DNA complexed with natural and synthetic polyamines.
23. The 1982 revised criteria for the classification of systemic lupus erythematosus.
24. Enzyme immunoassay for antibodies to native DNA: specificity and quality of antibodies.
25. An improved ELISA for anti‐native DNA antibodies by elimination of interference by anti‐histone antibodies.
26. Polyamine oxidation down‐regulates IL‐2 production by human peripheral blood mononuclear cells.
27. Polyamine oxidases and oxidized polyamines
28. Immunological detection of B‐DNA to Z‐DNA transition of polynucleotides by immobilization of the DNA conformation on a solid support.
29. Recognition of Z‐RNA and Z‐DNA determinants by polyamines in solution: experimental and theoretical studies.
30. Facile transition of poly [d(TG) d(CA)] into a left‐handed helix in physiological conditions.
31. The antigenic determinants of denatured DNA reactive with lupus erythematosus serum.
32. Specificity of anti‐nucleoside antibodies in systemic lupus erythematosus.
33. Specificity of monoclonal anti‐Z‐DNA antibodies from unimmunized MRL/Mp‐lpr/lpr mice. J.
34. Murine models of systemic lupus erythematosus.
35. The anatomy of A‐, B‐ and Z‐DNA.
36. The chemistry and biology of left‐handed Z‐DNA.
37. Structural basis for stabilization of Z‐DNA by cobalt hexamine and magnesium cations.