Effect of Topical Cyclosporine Rinse on Oral Lichen Planus: A Double-Blind Analysis

New England Journal of Medicine

Volumn 323, Issue 5, 1990, Pages 290-294

  Eisen, Drore ^a   Ellis, Charles N ^a   Duell, Elizabeth A ^a   Griffiths, Christopher E m ^a   Voorhees, John J ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN; CYCLOSPORIN A;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HUMAN; LICHEN PLANUS; MALE; MOUTH DISEASE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; TOPICAL DRUG ADMINISTRATION;

AGED; CYCLOSPORINS; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; HUMAN; LICHEN PLANUS; MALE; MIDDLE AGE; MOUTH DISEASES; MOUTH MUCOSA; MOUTHWASHES; RANDOMIZED CONTROLLED TRIALS; SUPPORT, NON-U.S. GOV'T;

EID: 0025347974     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJM199008023230502     Document Type: Article

References (24)

1. Axell T, Rundquist L. Oral lichen planus — a demographic study. Community Dent Oral Epidemiol 1987; 15: 52–6.
2. Thom JJ, Holmstrup P, Rindum J, Pindborg JJ. Course of various clinical forms of oral lichen planus: a prospective follow-up study of 611 patients. J Oral Pathol 1988; 17: 213–8.
3. Frances C, Boisnic S, Etienne S, Szpirglas H. Effect of the local application of ciclosporine A on chronic erosive lichen planus of the oral cavity. Dermatologica 1988; 177: 194–5.
4. Balato N, De Rosa S, Bordone F, Ayala F. Dermatological application of cyclosporine. Arch Dermatol 1989; 125: 1430–1.
5. Eisen D, Griffiths CEM, Ellis CN, Nickoloff BJ, Voorhees JJ. Cyclosporin wash for oral lichen planus. Lancet 1990; 335: 535–6.
6. Andreasen JO. Oral lichen planus. 1. A clinical evaluation of 115 cases. Oral Surg Oral Mcd Oral Pathol 1968; 25: 31–42.
7. Annesley T, Matz K, Balogh L, Clayton L, Giacherio D. Liquid-chromatographic analysis for cyclosporine with use of a microbore column and small sample volume. Clin Chem 1986; 32: 1407–9.
8. Fisher GJ, Duell EA, Nickoloff BJ, et al. Levels of cyclosporin in epidermis of treated psoriasis patients differentially inhibit growth of keratinocytes cultured in serum free versus serum containing media. J Invest Dermatol 1988; 91: 142–6.
9. Bagan JV, Silvestre FJ, Mestre S, Gisbert C, Bermejo A, Agramunt J. Treatment of lichen planus with griseofulvin: report of seven cases. Oral Surg Oral Med Oral Pathol 1985; 60: 608–10.
10. Beck HI, Brandrup F. Treatment of erosive lichen planus with dapsone. Acta Derm Venereol (Stockh) 1986; 66: 366–7.
11. Bollag W, Ott F. Treatment of lichen planus with temarotene. Lancet 1989; 2: 974.
12. Conklin RJ, Blasberg B. Oral lichen planus. Dermatol Clin 1987; 5: 663–73.
13. Pigatto PD, Chiappino G, Bigardi A, Mozzanica N, Finzi AF. Cyclosporin A for treatment of severe lichen planus. Br J Dermatol 1990; 122: 121–3.
14. Gupta AK, Brown MD, Ellis CN, et al. Cyclosporine in dermatology. J Am Acad Dermatol 1989; 21: 1245–56.
15. Lehtinen R, Happonen RP, Kuusilehto A, Jansen C. A clinical trial of PUVA treatment in oral lichen planus. Proc Finn Dent Soc 1989; 85: 29–33.
16. Takeuchi Y, Tohnai I, Kaneda T, Nagura H. Immunohistochemical analysis of cells in mucosal lesions of oral lichen planus. J Oral Pathol 1988; 17: 367–73.
17. Nickoloff BJ. Role of interferon-gamma in cutaneous trafficking of lymphocytes with emphasis on molecular and cellular adhesion events. Arch Dermatol 1988; 124: 1835–43.
18. Wagner H. Cyclosporin A: mechanism of action. Transplant Proc 1983; 15: 523–6.
19. Abb J, Abb H. Effect of cyclosporine on human leukocyte interferon production: selective inhibition of IFN-gamma synthesis. Transplant Proc 1983; 15: Suppl 1: 2380–2.
20. Gilhar A, Pillar T, Etzioni A. Topical cyclosporine A in alopecia areata. Acta Derm Venereol (Stockh) 1989; 69: 252–3.
21. Gilhar A, Winterstein G, Golan DT. Topical cyclosporine in psoriasis. J Am Acad Dermatol 1988; 18: 378–9.
22. Hermann RC, Taylor RS, Ellis CN, et al. Topical ciclosporin for psoriasis: in vitro skin penetration and clinical study. Skin Pharmacol 1988; 1: 246–9.
23. Grattan CEH, Boon AP, Gregory J. A preliminary open study of topical cyclosporin for hypertrophic lichen planus. J Dermatol Treat 1989; 1: 39–41.
24. Lin SC, Hahn LJ, Kwan HW. Subsets of T lymphocytes in peripheral blood of patients with oral lichen planus. Int J Oral Maxillofac Surg 1988; 17: 84–6.