NE-19550 and NE-21610, antinociceptive capsaicin analogues: studies on nociceptive fibres of the neonatal rat tail in vitro

European Journal of Pharmacology

Volumn 181, Issue 3, 1990, Pages 289-293

  Dray, A ^a   Bettaney, J ^a   Rueff, A ^a   Walpole, C ^a   Wrigglesworth, R ^a  

^a Sandoz Institute for Medical Research   (United Kingdom)

Author keywords

Antinociception; Capsaicin; NE 19550; NE 21610; Nociceptors

Indexed keywords

BRADYKININ; CAPSAICIN; NUVANIL; OLVANIL;

ANIMAL CELL; ARTICLE; DRUG CONCENTRATION; NEWBORN; NOCICEPTIVE STIMULATION; NONHUMAN; PERIPHERAL NERVE; PRIORITY JOURNAL; RAT; SPINAL CORD; TAIL;

ANIMAL; ANIMALS, NEWBORN; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CAPSAICIN; HEAT; IN VITRO; NEURONS; NOCICEPTORS; PERIPHERAL NERVES; RATS; SPINAL CORD; TAIL;

EID: 0025345294     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(90)90091-J     Document Type: Article

References (10)

1. Pharmacologic profile of NE-12610, a new analgesic
2. Calcium and the effects of capsaicin on afferent fibres in a neonatal rat isolated spinal cord-tail preparation
3. 19550: a novel orally active anti-inflammatory analgesic
4. Comparison of capsaicin and olvanil as antinociceptive agents in vivo and in vitro
5. Capsaicin-induced antinociception: central and peripheral sites of action
6. Capsaicin desentization of peripheral nociceptive fibres does not impair sensitivity to other noxious stimuli
7. The effects of a series of capsaicin analogues on nociception and body temperature
8. Specific binding of resiniferatoxin, an ultrapotent capsaicin analog, to dorsal root ganglion membranes
9. Sensory effects of capsaicin congeners I. Relationship between chemical structure and pain-producing potency of pungent agents
10. Capsaicin-induced ion fluxes in dorsal root ganglion cells in culture