Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor

Cell

Volumn 60, Issue 6, 1990, Pages 953-962

  Fawell, Stephen E ^a   Lees, Jacqueline A ^a   White, Roger ^a   Parker, Malcolm G ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR;

ANIMAL CELL; ARTICLE; DIMERIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMAL; ANTIBODIES; BASE SEQUENCE; BINDING SITES; CHROMOSOME DELETION; COMPARATIVE STUDY; LIGANDS; MACROMOLECULAR SYSTEMS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; OLIGONUCLEOTIDE PROBES; OLIGOPEPTIDES; RECEPTORS, ESTROGEN; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANSCRIPTION, GENETIC; TRANSLATION, GENETIC;

ANIMALIA;

EID: 0025329841     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(90)90343-D     Document Type: Article

References (74)

1. Cloning of human miner-alocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor
2. Cloning and expression of full-length cDNA encoding human vitamin D receptor
3. 1 form of uteroglobin at 1.64 Å resolution
4. Gene regulation by steroid hormones
5. Binding of progesterone to the proteins of the uterine luminal fluid
6. A new retinoic acid receptor identified from a hepatocellular carcinoma
7. Identification of a second human retinoic acid receptor
8. Structural analysis of complementary DNA and amino acid sequences of human and rat androgen receptors
9. α-Helical coiled coils—a wide-spread motif in proteins
10. The mouse glucocorticoid receptor: mapping of functional domains by cloning, sequencing and expression of wild-type and mutant receptor proteins
11. Two amino acids within the knuckle of the first zinc finger specify DNA response element activation by the glucocorticoid receptor
12. The steroid and thyroid hormone receptor superfamily
13. Androgen regulation of specific mRNAs, endoplasmic reticulum and Golgi-system
14. A proposed consensus steroid-binding sequence—a reply
15. A domain containing a leucine-zipper-like motif mediates novel in vivo interactions between the thyroid hormone and retinoic acid receptors
16. The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain
17. Parallel association of Fos and Jun leucine zippers juxtaposes DNA binding domains
18. Functional domains of the human glucocorticoid receptor
19. Identification of a receptor for the morphogen retinoic acid
20. Identification of a new class of steroid hormone receptors
21. Computer modeling of estradiol interactions with the estrogen receptor
22. Oestradiol induction of a glucocorticoid-responsive gene by a chimaeric receptor
23. Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A
24. The chicken progesterone receptor: sequence, expression and functional analysis
25. Mechanisms of nuclear localization of the progesterone receptor: evidence for interaction between monomers
26. Regulation of gene expression by nuclear hormone receptors
27. Characterization of response elements for androgens, glucocorticoids and progestins in mouse mammary tumour virus
28. Identification of cysteine 530 as the covalent attachment site of an affinity-labeling estrogen (ketononestrol aziridine) and antiestrogen (tamoxifen aziridine) in the human estrogen receptor
29. A gene inducible by serum growth factors encodes a member of the steroid and thyroid hormone receptor superfamily
30. Primary structure and expression of a functional human glucocorticoid receptor cDNA
31. Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor
32. Structure of the chromosomal chicken progesterone receptor gene
33. Molecular cloning and characterization of rat estrogen receptor cDNA
34. The role of the leucine zipper in the fos-jun interaction
35. The chicken oestrogen receptor sequence: homology with v-erb A and the human oestrogen and glucocorticoid receptors
36. The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer
37. Functional domains of the human estrogen receptor
38. The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins
39. The DNA binding domain of the rat liver nuclear protein C/EBP is bipartite
40. Identification of two transactivation domains in the mouse oestrogen receptor
41. Analysis of monomeric-dimeric states of the estrogen receptor with monoclonal antiestrophilins
42. Cloning and sequence analysis of rabbit progesterone-receptor complementary DNA
43. Three amino acids of the oestrogen receptor are essential to its ability to distinguish an oestrogen from a glucocorticoid-responsive element
44. Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter
45. Genetic complementation of a glucocorticoid receptor deficiency by expression of cloned receptor cDNA
46. Glucocorticoid receptor mutants that define a small region sufficient for enhancer activation
47. Complete amino acid sequence of the human progesterone receptor deduced from cloned cDNA
48. Identification of two novel members of erbA superfamily by molecular cloning: the gene products of the two are highly related to each other
49. 1 crystal form of oxidized uteroglobin at 1.34 Å resolution
50. X-ray crystallographic analysis of a progesterone-binding protein
51. A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughter-less, MyoD, and myc proteins
52. Evidence that the leucine zipper is a coiled coil
53. A human retinoic acid receptor which belongs to the family of nuclear receptors
54. Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor
55. Genomic organization of the human oestrogen receptor gene
56. Fos-Jun interaction: mutational analysis of the leucine zipper domain of both proteins
57. The interaction site for tamoxifen aziridine with the bovine estrogen receptor
58. Functional dissection of the hormone and DNA binding activities of the glucocorticoid receptor
59. The estrogen-responsive DNA element: structure and interaction with the estrogen receptor
60. The c-erb-A protein is a high-affinity receptor for thyroid hormone
61. Molecular model of the interaction between glucocorticoid receptor and the regulatory elements of inducible genes
62. The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate-modified DNA
63. The N-terminal region of the chicken progesterone receptor specifies target gene activation
64. Identification of a novel thyroid hormone receptor expressed in the mammalian central nervous system
65. Molecular interactions of steroid hormone receptor with its enhancer element: evidence for receptor dimer formation
66. Determinants of target gene specificity for steroid/thyroid hormone receptors
67. COUP transcription factor is a member of the steroid receptor superfamily
68. A single domain of the estrogen receptor confers deoxyribonucleic acid binding and transcriptional activation of the rat prolactin gene
69. The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function
70. The Xenopus laevis estrogen receptor: sequence homology with human and avian receptors and identification of multiple estrogen receptor messenger ribonucleic acids
71. The c-erb-A gene encodes a thyroid hormone receptor
72. Structural organization and expression of the mouse estrogen receptor
73. Steroid receptor regulated transcription of specific genes and gene networks
74. Cloning of murine α and β retinoic acid receptors and a novel receptor γ predominantly expressed in skin