Serotonin as a growth factor

Biochemical Pharmacology

Volumn 39, Issue 6, 1990, Pages 985-990

  Seuwen, Klaus ^a   Pouysségur, Jacques ^a  

^a CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; CLONIDINE; CYCLIC AMP; GROWTH FACTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL PHOSPHATE; RECEPTOR SUBTYPE; SEROTONIN; SEROTONIN RECEPTOR; THROMBIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; DNA SYNTHESIS; FIBROBLAST; HAMSTER; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMAL; CELL DIVISION; CYCLIC AMP; GROWTH SUBSTANCES; GTP-BINDING PROTEINS; HUMAN; ONCOGENES; RECEPTORS, SEROTONIN; SEROTONIN; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T;

EID: 0025329805     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(90)90276-Q     Document Type: Article

References (65)

1. Vasoactive effects of growth factors
2. Stimulation of aortic smooth muscle cell mitogenesis by serotonin
3. Serotonin-induced deoxyribonucleic acid synthesis in vascular smooth muscle cells involves a novel, pertussis toxin-sensitive pathway
4. i-protein
5. endothelium, platelets and vasospasm
6. A role for neuropeptides in the control of cell proliferation
7. Serum, bradykinin and vasopressin stimulate release of inositol phosphates from human fibroblasts
8. Mitogenic activity of blood components. I. Thrombin and prothrombin
9. Growth factor requirements of Chinese hamster lung fibroblasts in serum free media high mitogenic action of thrombin
10. Thrombin as a growth factor: Mechanism of signal transduction
11. i-mediated inhibition of human platelet adenylate cyclase by thrombin
12. Phosphoinositides in mitogenesis: neomycin inhibits thrombin-stimulated phosphoinositide turnover and initiation of cell proliferation
13. + exchange in hamster fibro-blasts
14. Thrombin exerts a dual effect on stimulated adenylate cyclase in hamster fibroblasts: an inhibition via a GTP-binding protein and a potentiation via activation of protein kinase C
15. Phosphatidylinositol metabolism in rat hepatocytes stimulated by vasopressin
16. Vasopressin inhibits the adenylate cyclase activity of human platelet particulate fraction through V1-receptors
17. Reduction of epidermal growth factor receptor affinity by heterologous ligands: evidence for a mechanism involving the breakdown of phosphoinositides and the activation of protein kinase C
18. Receptor-mediated inhibition of adenylate cyclase and stimulation of arachidonic acid release in 3T3 fibroblasts.Selective susceptibility to islet-activating protein, pertussis toxin.
19. Adrenergic receptors. Models for the study of receptors coupled to guanine nucleotide regulatory proteins
20. Functionally distinct G proteins selectively couple different receptors to PI hydrolysis in the same cells
21. p
22. G proteins and dual control of adenylate cyclase
23. Isolation, sequence analysis, and intronexon arrangement of the gene encoding bovine rhodopsin
24. Molecular characterization of a functional cDNA encoding the serotonin 1c receptor
25. 2 receptor
26. 1A receptor
27. Growth factor receptor tyrosine kinases
28. Transmembrane signalling pathways initiating cell growth in fibroblasts
29. 2+ in quiescent 3T3 cells stimulated by platelet-derived growth factor, bombesin and vasopressin
30. The pathway of phospholipase C activation initiated with platelet-derived growth is different from that initiated with vasopressin and bombesin
31. ++ mobilization and cellular responses by leukocytes
32. Pertussis toxin does not inhibit muscarinic-receptor-mediated phosphoinositide hydrolysis or calcium mobilization
33. Islet-activating protein, pertussis toxin: a probe for functions of the inhibitory guanine nucleotide regulatory component of adenylate cyclase
34. Direct modification of the membrane adenylate cyclase system by islet-activating protein due to ADP-ribosylation of a membrane protein
35. Identification of the predominant substrate for ADP-ribosylation by islet activating protein
36. Two growth factor signalling pathways in fibroblasts distinguished by pertussis toxin
37. Pertussis toxin-sensitive pathway in the stimulation of c-myc expression and DNA synthesis by bombesin
38. 4-induced phosphoinositide breakdown in hamster fibroblasts: evidence for positive cross-talk between the two mitogenic signaling pathways
39. 1c receptors
40. Molecular biology of 5-HT receptors
41. 2 receptor binding sites. Binding properties, brain distribution, and functional role
42. 2 receptor sites
43. 1B receptors are negatively coupled with adenylate cyclase in rat substantia nigra
44. Role of cyclic nucleotides in growth control
45. Cyclic AMP: a mitogenic signal for Swiss 3T3 cells
46. The cyclic AMP-mediated stimulation of cell proliferation
47. 1
48. Cyclic AMP inhibits mitogen-induced DNA synthesis in hamster fibroblasts, regardless of the signalling pathway involved
49. Cyclic GMP cascade of vision
50. Inhibition of adenylate cyclase by adenosine analogues in preparations of broken and intact human platelets. Evidence for the unidirectional control of platelet function by cyclic AMP
51. 2-adrenergic inhibition of insulin release
52. i α-subunits
53. 2 activity in bovinc rod outer segments by the βγ subunits of transducin and its inhibition by the α subunit
54. A novel viral oncogene with structural similarity to phospholipase C
55. Species differences in the pharmacology of terminal 5-HT autoreceptors in mammalian brain
56. 1D receptor-mediated inhibition of forskolin-stimulated adenylate cyclase activity in calf substantia nigra
57. Cloning, sequencing, and expression of the gene coding for the human platelet α-adrenergic receptor
58. Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors
59. Serotonin as a major serum factor inducing the phospholipase C-mediated hydrolysis of phosphoinositides in normal rat kidnev cells
60. Stimulation of DNA synthesis by tumour promoter and pure mitogenic factors
61. Isolation and characterization of a new cellular oncogene encoding a protein with multiple transmembrane domains
62. The mas oncogene encodes an angiotensin receptor
63. Ectopic expression of the serotonin 1c receptor and the triggering of malignant transformation
64. Structures of the genes coding for G protein α subunits from mammalian and yeast cells