Epitope mapping of the HIV-1 gag region with monoclonal antibodies

Molecular Immunology

Volumn 27, Issue 5, 1990, Pages 395-403

  Hinkula, J ^a   Rosen, J ^b   sundqvist, V A ^a   Stigbrand, T ^c   Wahren, B ^a  

^a National Bacteriological Laboratory   (Sweden)

^b JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

^c UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; SYNTHETIC PEPTIDE; VIRUS ANTIGEN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BIOLOGICAL MODEL; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNOGENETICS; MOUSE; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMAL; ANTIBODIES, MONOCLONAL; BINDING, COMPETITIVE; BLOTTING, WESTERN; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; GENE PRODUCTS, GAG; HIV ANTIGENS; HIV-1; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; RECOMBINANT PROTEINS;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0025321139     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/0161-5890(90)90163-T     Document Type: Article

References (27)

1. Fine specificity of IgG subclass response to group antigens in HIV infected patients
2. Rapid characterization of protein epitopes recognized by monoclonal antibodies using direct probing on thin-layer and paper chromatograms
3. Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS
4. Fine structure of human immunodeficiency virus (HIV), immunolocalization of structural proteins and virus-cell relation
5. Strategies for cpitope analysis using peptide synthesis
6. Human T-cell lymphotroplc virus type III (HTLV-III) core antigens: synthesis in Escherichia coli and immunoreactivity with human sera
7. Diagnoses of AIDS by using a 12-amino acid peptide representing an immunodominant epitope of the human immunodeficiency virus
8. Prediction of protein antigenic determinants from amino acid sequences
9. General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen antibody interaction at the level of individual amino acids
10. A simple method for displaying the hydropathic character of a protein
11. Reactivity of an HIV gag gene polypeptide expressed in E. coli with sera from AIDS patients and monoclonal antibodies to gag
12. Prediction of immunodominant helper T cell antigenic sites from the primary sequence
13. Solid phase peptide synthesis. I. The synthesis of a tetrapeptide
14. Comparison of different methods for localizing antigenic regions in histone H2A
15. Guidelines for the production of polypeptide specific antisera using small synthetic oligopeptides as immunogens
16. Complete nucleotide sequence of the AIDS virus, HTLV-III
17. Antibodies to HTLV-III in Swiss patients with AIDS and pre-AIDS and in groups at risk for AIDS
18. Distinction of epitopes by monoclonal antibodies
19. HIV-1 p24 antigen variation in tissue culture of isolates with defined growth characteristics
20. Antibodies that react with predetermined sites on proteins
21. Biochemical and immunological analysis of human immunodeficiency virus gag gene products p17 and p24
22. Characteristics of the specific cell-mediated immune response in human immunodeficiency virus infection
23. HIV-1 peptides inducing a proliferation response in lymphocytes from infected persons
24. Correlation between segmental mobility and the location of antigenic determinants in proteins