A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting

Nature

Volumn 345, Issue 6270, 1990, Pages 78-80

  DeChiara, Thomas M ^a   Efstratiadis, Argiris ^a   Robertsen, Elizabeth J ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN B;

ANIMAL EXPERIMENT; ARTICLE; EMBRYO; EMBRYO GROWTH; GENE FUNCTION; GROWTH RETARDATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ANIMAL; BASE SEQUENCE; BLASTOCYST; CELLS, CULTURED; CHIMERA; EMBRYO AND FETAL DEVELOPMENT; FEMALE; GROWTH DISORDERS; HETEROZYGOTE; INSULIN-LIKE GROWTH FACTOR II; MALE; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MUTATION; PIGMENTATION; POLYMERASE CHAIN REACTION; SOMATOMEDINS; STEM CELLS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

ANIMALIA; CHIMAERIFORMES; RODENTIA;

EID: 0025320906     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/345078a0     Document Type: Article

References (30)

1. Milner, R. D. G. & Hill, D. J. Clin Endocrinol. 21, 415-433 (1984).
2. Whitman, M. & Melton, D. A. A. Rev. Cell Biol. 5, 93-117 (1989).
3. Zapf, J. & Froesch, E. R. Hormone Res. 24, 121-130 (1986).
4. Daughaday, W. H. & Rotwein, P. Endocr. Rev. 10, 68-91 (1989).
5. Soares, M. B. et al., J. molec. Biol. 192, 737-752 (1986).
6. Sussenbach, J. S. Prog. Growth Factor Res. 1, 33-48 (1989).
7. Gammeltoft, S. in Peptide Hormones as Prohormones (ed. Martinez, J.) 176-210 (Halsted, New York, 1989).
8. Evans, T., DeChiara, T. & Efstratiadis, A. J. molec. Biol. 199, 61-81 (1988).
9. Ueno, T., Takahashi, K., Matsuguchi, T., Endo, H. & Yamamoto, M. Biochem. biophys. Res. Commun. 148, 344-349 (1987).
10. Stylianopoulou, F., Efstratiadis, A., Herbert, J. & Pintar, J. Development 103, 497-506 (1988).
11. Stylianopoulou, F., Herbert, J., Soares, M. B. & Efstratiadis, A. Proc. natn. Acad. Sci. U.S.A. 85, 141-145 (1988).
12. Evans, M. J. & Kaufman, M. H. Nature 292, 154-156 (1981).
13. Martin, G. Proc. natn. Acad. Sci. U.S.A. 78, 7634-7638 (1981).
14. Robertson, E. J. & Bradley, A. in Experimental Approaches to Mammalian Embryonic Development (eds Rossant, J. & Pedersen, R. A.) 475-508 (Cambridge University Press, Cambridge, 1986).
15. Smithies, O., Gregg, R. G., Boggs, S. S., Koralewski, M. A. & Kucherlapati, R. S. Nature 217, 230-234 (1985).
16. Thomas, K. R. & Capecchi, M. R. Cell 51, 503-512 (1987).
17. Mansour, S. L., Thomas, K. R. & Capecchi, M. R. Nature 336, 348-352 (1988).
18. Capecchi, M. Science 244, 1288-1292 (1989).
19. Doetschman, T., Maeda, N. & Smithies, O. Proc. natn. Acad. Sci. U.S.A. 85, 8583-8587 (1988).
20. Zimmer, A. & Gruss, P. Nature 338, 150-153 (1989).
21. Joyner, A. L., Skarnes, W. C. & Rossant, J. Nature 338, 153-156 (1989).
22. Johnson, R. S. et al. Science 245, 1234-1236 (1989).
23. Koller, B. H. & Smithies, O. Proc. natn. Acad. Sci. U.S.A. 86, 8932-8935 (1989).
24. Zijlstra, M., Li, E., Sajjadi, F., Subramani, S. & Jaenisch, R. Nature 342, 435-488 (1989).
25. Schwartzberg, P. L. Goff, S. P. & Robertson, E. J. Science 246, 799-803 (1989).
26. Bradley, A., Evans, M., Kaufman, M. H. & Robertson, E. Nature 309, 255-256 (1984).
27. Robertson, E., Bradley, A., Kuehn, M. & Evans, M. Nature 323, 445-448 (1986).
28. Robertson, E. J. in Teratocarcinomas and Embryonic Stem Cells: A Practical Approach (ed. Robertson, E. J.) 71-112 (IRL, Oxford, 1987).
29. Marsh, J. L., Erfle, M. & Wykes, E. J. Gene 32, 481-485 (1984).
30. Kim, H.-S. & Smithies, O. Nucleic Acids Res. 16, 8887-8903 (1988).