DNA length polymorphism 5′ to the myelin basic protein gene is associated with multiple sclerosis

Annals of Neurology

Volumn 27, Issue 3, 1990, Pages 291-297

  Boylan, Kevin B ^a   Takahashi, Naoki ^c,d   Paty, Donald W ^b   Sadovnick, Adele D ^b   Diamond, Marc ^a   Hood, Leroy E ^c   Prusiner, Stanley B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MYELIN BASIC PROTEIN;

ADULT; ARTICLE; DNA POLYMORPHISM; FEMALE; HISTOCHEMISTRY; HUMAN; MALE; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; ULTRASTRUCTURE;

ADULT; AGED; FEMALE; HUMAN; MALE; MIDDLE AGE; MULTIPLE SCLEROSIS; MYELIN BASIC PROTEINS; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0025317768     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.410270311     Document Type: Article

References (36)

1. Multiple sclerosis
2. The mystery of the origin of muiltiple sclerosis
3. Epidemiology of multiple sclerosis
4. The familial nature of multiple sclerosis: age‐corrected empiric recurrence risks for children and siblings of patients
5. A population based study of multiple sclerosis in twins
6. The genetics of multiple sclerosis: the HLA system and other genetic markers
7. Familial multiple sclerosis: clinical, histocompatibility, and viral serological studies
8. Genetic markers in neurological diseases
9. Susceptibility to multiple sclerosis associated with an immunoglobulin gamma 3 fragment length polymorphism
10. Assessing the role of HLA‐linked and unlinked determinants of disease
11. Genetic analysis workshop IV: summary of the multiple sclerosis workshop
12. Multiple sclerosis (second of two parts)
13. Mechanisms in multiple sclerosis
14. Autoimmunity in multiple sclerosis: do we have an experimental model?
15. Cellular immunity in multiple sclerosis Br
16. Relevance of experimental allergic encephalomyelitis to multiple sclerosis
17. Immunoregulatory mechanisms in experimental autoimmune encephalomyelitis and multiple sclerosis
18. Immunopathological comparisons between experimental autoimmune encephalomyelitis and multiple sclerosis
19. Multiple sclerosis: evidence for immunopathogenesis
20. CSF antibody to myelin basic protein, measurement in patients with multiple sclerosis and subacute sclerosing panencephalitis
21. The immunology of multiple sclerosis
22. Identity of myelin basic protein from multiple sclerosis and human control brain: discovery of a genetic variant
23. Immune response of Lewis rats to peptide C1 (residues 68‐88) of guinea pig and rat myelin basic proteins
24. Amino acid homology between the encephalitogenic site of myelin basic protein and virus: mechanism for autoimmunity
25. Polymorphism of DNA sequence adjacent to human β‐globin structural gene: relationship to sickle mutation
26. Polymorphism in the 5′ flanking region of the human insulin gene: a genetic marker for non‐insulin‐dependent diabetes
27. DNA polymorphisms of the apolipoprotein AII and AI‐CIII‐AVI genes: a study in men selected for differences in high‐density‐lipoprotein cholesterol concentration
28. The human myelin basic protein gene: chromosomal localization and RFLP analysis
29. DNA length polymorphism located 5′ to the human myelin basic protein gene
30. Region of DNA length polymorphism 5′ to the human myelin basic protein gene is composed of oligonucleotide tetramer repeats
31. New diagnostic criteria for multiple sclerosis, guidelines for research protocols
32. Triggering factors in multiple sclerosis
33. n 5′ to the human myelin basic protein gene: a new form of oligonucleotide repetitive sequence showing length variation
34. Cloning and characterization of the myelin basic protein gene from mouse: one gene can encode both 14 kd and 18.5 kd MPBs by alternate use of exons
35. Localization of the human myelin basic protein gene (MBP) to region 18q22→qter by in situ hybridization