Mechanism of the inhibition by insulin of the glucagondependent activation of the phosphoe/ol/pyruvate carboxykinase gene in rat hepatocyte cultures action on gene transcription, mrna level and -stability as well as hysteresis effect;Mechanismus der hemmung der glucagonabhängigen aktivierung des phosphoeno\pyruvat-carboxykinase-gens durch insulin in rattenhepatozytenkulturen. wirkung auf die gentranskription, den mrna-gehalt und die mrna-stabilität sowie hysterese-effekt.

Biological Chemistry Hoppe-Seyler

Volumn 371, Issue 1, 1990, Pages 395-402

  Christ, Bruno ^a   Nath, Annegret ^a   Jungermann, Kurt ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

glucagon; hepatocyte cultures; insulin; Mrnalevel; Phosphoeno pyruvate carboxykinase; transcriptional rate

Indexed keywords

GLUCAGON; INSULIN; MESSENGER RNA; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP);

ANIMAL CELL; ARTICLE; CELL CULTURE; DNA TRANSCRIPTION; HYSTERESIS; LIVER CELL; NONHUMAN; RAT; RNA STABILITY;

ANIMAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; GLUCAGON; INSULIN; LIVER; MALE; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); RATS; RATS, INBRED STRAINS; RNA, MESSENGER; SUPPORT, NON-U.S. GOV'T; TIME FACTORS; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 0025316920     PISSN: 01773593     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/bchm3.1990.371.1.395     Document Type: Article

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