The colony stimulating factors discovery, development, and clinical applications

Cancer

Volumn 65, Issue 10, 1990, Pages 2185-2195

  Metcalf, Donald ^a  

^a ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

COLONY STIMULATING FACTOR 1; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 3;

CONFERENCE PAPER; HUMAN; MYELOID LEUKEMIA; PRIORITY JOURNAL;

ANIMAL; CELL DIVISION; CHEMISTRY; COLONY-STIMULATING FACTORS; HUMAN; LEUKEMIA, MYELOID; RECOMBINANT PROTEINS;

EID: 0025308898     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/1097-0142(19900515)65:10<2185::AID-CNCR2820651005>3.0.CO;2-4     Document Type: Article

References (105)

1. The growth of mouse bone marrow cells in vitro
2. The induction of clones of normal “mast” cells by a substance from conditioned medium
3. Factors from mouse tissues stimulating colony growth of mouse bone marrow cells in vitro
4. Stimulation by normal and leukemic mouse sera of colony formation in vitro by mouse bone marrow cells
5. Human bone marrow colony growth in agar gel
6. In vitro growth of granulocytic and mononuclear cell colonies from blood of normal individuals
7. Induction of colonies of hemoglobin‐synthesizing cells by erythropoietin in vitro
8. Growth of murine megakaryocyte colonies in vitro
9. The presence of mast cells in agar cultures
10. Detection of a new type of mouse eosinophil colony by Luxol‐Fast‐Blue staining
11. Tissue sources of bone marrow colony stimulating factor
12. Bone marrow colony stimulating activity in human sera
13. Bone marrow colony stimulating activity of sera in infectious mononucleosis
14. Hemopoietic colony‐forming cell responses in mice infected with ectromelia virus
15. Granulocyte‐macrophage precursor cell and colony‐stimulating factor responses of mice infected with Salmonella typhimurium
16. Acute antigen‐induced elevation of serum colony stimulating factor (CSF) levels
17. Stimulation of bone marrow colony growth in vitro by human urine
18. Colony stimulating factor and the regulation of granulopoiesis and macrophage production
19. Stimulation by human urine or plasma of granulopoiesis by human marrow cells in agar
20. Factors regulating macrophage production and growth. Purification and some properties of the colony stimulating factor from medium conditioned by mouse L cells
21. A low molecular weight factor in lung‐conditioned medium stimulating granulocyte and monocyte colony formation in vitro
22. Purification and properties of colony‐stimulating factor from mouse lung conditioned medium
23. Purification and partial amino acid sequence of asialo murine granulocyte‐macrophage colony stimulating factor
24. Preparation and neutralization characteristics of an anti‐CSF antibody
25. Characterization of a serum factor stimulating the differentiation of myelomonocytic leukemic cells
26. Purification of a factor inducing differentiation in murine myelomonocytic leukemia cells: Identification as granulocyte colony‐stimulating factor
27. Colony formation in vitro by myelomonocytic leukemic cells
28. Production of colony stimulating factors in mitogen‐stimulated lymphocyte cultures
29. Formation of eosinophilic‐like granulocyte colonies by mouse bone marrow cells in vitro
30. Production by spleen and lymph node cells of conditioned medium with erythroid and other hemopoietic colony‐stimulating activity
31. Pure and mixed erythroid colony formation in vitro stimulated by spleen conditioned medium with no detectable erythropoietin
32. Selective stimulation by mouse spleen cell conditioned medium of human eosinophil colony formation
33. Characterization and partial purification of a haemopoietic growth factor in WEHI‐3 conditioned medium
34. Molecules stimulating early red cell, granulocyte, macrophage and megakaryocyte precursors in culture: Similarity in size, hydrophobicity and charge
35. Purification of a multipotential colony stimulating factor from pokeweed mitogen‐stimulated mouse spleen cell conditioned medium
36. Procedures for the purification of interleukin 3 to homogeneity
37. The molecular cloning of interleukins 4 and 6: Multifunctional hemopoietic growth factors
38. Effect of interleukin‐6 (IL‐6) on the differentiation and proliferation of murine and human hemopoietic progenitors
39. Actions and interactions of G‐CSF, LIF and IL‐6 on normal and leukemic murine cells
40. Purified human granulocyte‐macrophage colony‐stimulating factor: direct action on neutrophils
41. Purification and characterization of human granulocyte colony‐stimulating factor (G‐CSF)
42. Purification and biochemical characterization of human pluripotent hematopoietic colony‐stimulating factor
43. Molecular cloning of a cDNA encoding a murine haematopoietic growth regulator, granulocyte‐macrophage colony‐stimulating factor
44. Isolation and characterization of the cDNA for murine granulocyte colony‐stimulating factor
45. Nucleotide sequence of a cDNA encoding murine CSF‐1 (macrophage CSF)
46. Isolation and characterization of a mouse cDNA clone that expresses mast cell growth factor activity in monkey cells
47. Molecular cloning of cDNA for mouse interleukin‐3
48. Human GM‐CSF: Molecular cloning of the complementary DNA and purification of the natural and recombinant protein
49. Molecular cloning and expression of cDNA for human granulocyte colony‐stimulating factor
50. Recombinant human granulocyte colony‐stimulating factor: Effects on normal and leukemic myeloid cells
51. Molecular cloning of a complementary DNA encoding human macrophage‐specific colony‐stimulating factor (CSF‐1)
52. Human IL‐3 (Multi‐CSF): Identification by expression cloning of a novel hematopoietic growth factor related to murine IL‐3
53. Hemopoietic cell growth factors and their receptors
54. The c‐fms proto‐oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF‐1
55. Expression cloning of a receptor for human granulocyte‐macrophage colony‐stimulating factor
56. Functional, morphologic and kinetic analysis of the granulocyte‐macrophage progenitor cell
57. Clonal analysis of proliferation and differentiation of paired daughter cells: Action of granulocyte‐macrophage colony‐stimulating factor on granulocyte‐macrophage precursors
58. Multi‐CSF‐dependent colony formation by cells of a murine hemopoietic cell line: Specificity and action of Multi‐CSF
59. Recombinant human macrophage colony stimulating factor (M‐CSF) requires subliminal concentrations of granulocyte/macrophage (GM)‐CSF for optimal stimulation of human macrophage colony formation in vitro
60. Human granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) stimulates immature marrow precursors but no CFU‐GM, CFU‐G or CFU‐M
61. Hierarchical down‐modulation of hemopoietic growth factor receptors
62. The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells
63. Biological activities of recombinant human granulocyte colony stimulating factor (rhG‐CSF) and tumor necrosis factor: In vivo and in vitro analysis
64. Hemopoietic responses in mice injected with purified recombinant murine GM‐CSF
65. Effects of purified bacterially synthesized murine Multi‐CSF (IL‐3) on hematopoiesis in normal adult mice
66. Quantitative responsiveness of murine hemopoietic populations in vitro and in vivo to recombinant Multi‐CSF (IL‐3)
67. Protective effect of human granulocyte colony‐stimulating factor on microbial infection in neutropenic mice
68. Protective, restorative and therapeutic properties of recombinant colony stimulating factors
69. Stimulation of hae‐matopoiesis in primates by continuous infusion of recombinant human GM‐CSF
70. Recombinant human granulocyte colony‐stimulating factor. Effects on hematopoiesis in normal and cyclophosphamide‐treated primates
71. Effects of recombinant human granulocyte‐macrophage colony‐stimulating factor on myelopoiesis in the acquired immunodeficiency syndrome
72. Effect of granulocyte colony‐stimulating factor on neutropenia induced by cytotoxic chemotherapy
73. Effect of granulocyte colony‐stimulating factor on neutropenia and associated morbidity due to chemotherapy for transitional cell carcinoma of the urothelium
74. Phase I/II study of recombinant human granulocyte colony‐stimulating factor in patients receiving intensive chemotherapy for small cell lung cancer
75. Effects of subcutaneously administered bacterially‐synthesized recombinant human granulocyte‐macrophage colony‐stimulating factor in patients with advanced malignancy
76. Effect of recombinant granulocyte‐macrophage colony‐stimulating factor on hematopoietic reconstitution after high‐dose chemotherapy and autologous bone marrow transplantation
77. Recombinant human granulocyte macrophage colony stimulating factor (rhGM‐CSF) given as daily short infusions–a phase I dose/toxicity study
78. Effect of recombinant human granulocyte‐macrophage colony‐stimulating factor on chemotherapy‐induced myelosuppression
79. Hematopoietic responses in patients with advanced malignancy treated with recombinant human granulocyte‐macrophage colony‐stimulating factor
80. Use of recombinant human granulocyte‐macrophage colony‐stimulating factor in autologous marrow transplantation for lymphoid malignancies
81. Effects of recombinant human granulocyte colony stimulating factor on neutropenia in patients with congenital agranulocytosis
82. Effects of recombinant human granulocyte‐macrophage colony‐stimulating factor in patients with myelodysplastic syndromes
83. Subcutaneous granulocyte‐macrophage colony‐stimulating factor in patients with myelodysplastic syndrome: Toxicity, pharmacokinetics and hematological effects
84. Recombinant human granulocyte‐macrophage colony‐stimulating factor in patients with myelodysplastic syndromes–A phase I/II trial
85. Phase I/II study of recombinant human granulocyte‐macrophage colony‐stimulating factor in aplastic anemia and myelodysplastic syndrome
86. Transgenic mice expressing a hemopoietic growth factor gene (GM‐CSF) develop accumulations of macrophages, blindness and a fatal syndrome of tissue damage
87. A lethal myeloproliferative syndrome in mice transplanted with bone marrow cells infected with a retrovirus expressing granulocyte‐macrophage colony stimulating factor
88. Long‐term exposure to retrovirally‐expressed G‐CSF induces a non‐neoplastic gran‐ulocytic and progenitor cell hyperplasia without tissue damage in mice
89. Non‐neoplastic hemopoietic myeloproliferative syndrome induced by dysregulated Multi‐CSF (IL‐3) expression
90. Expression of a hematopoietic growth factor cDNA in a factor‐dependent cell line results in autonomous growth and tumorigenicity
91. Generation of an autocrine leukemia using a retroviral expression vector carrying the interleukin‐3 gene
92. Autocrine stimulation after transfer of the granulocyte/macrophage colony‐stimulating factor gene and autonomous growth are distinct but interdependent steps in the oncogenic pathway
93. The roles of stem cell self‐renewal and autocrine growth factor production in the biology of myeloid leukemia
94. Constitutive expression of the granulocyte‐macrophage colony‐stimulating factor gene in acute myelo‐blastic leukemia
95. Constitutive expression of hematopoietic growth factor genes by acute myeloblastic leukemia cells
96. Regulator‐induced suppression of myelomonocytic leukemic cells: Clonal analysis of early cellular events
97. Prolongation of survival time of leukemic mice by the administration of recombinant human granulocyte colony stimulating factor
98. Purified colony stimulating factors (G‐CSF and GM‐CSF) induce differentiation in HL60 cells with suppression of clonogenicity
99. Clonal suppression of HL60 and U937 cells by recombinant leukemia inhibitory factor in combination with GM‐CSF or G‐CSF
100. Clonal analysis of the actions of murine leukemia inhibitory factor (LIF) on leukemic and normal murine hemopoietic cells
101. The myeloid blood cell differentiation‐inducing protein MGI‐2A is interleukin‐6