Effects of psychotropic drugs on the behavior and neurochemistry of olfactory bulbectomized rats

Pharmacology and Therapeutics

Volumn 47, Issue 1, 1990, Pages 21-34

  van Riezen, H ^a   Leonard, B E ^b  

^a CIBA GEIGY LTD   (Switzerland)

^b NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; PSYCHOTROPIC AGENT;

ANIMAL EXPERIMENT; BEHAVIOR; NEUROCHEMISTRY; NONHUMAN; OLFACTORY BULBECTOMY; PRIORITY JOURNAL; PSYCHOLOGICAL ASPECT; RAT; REVIEW;

ANIMAL; BEHAVIOR, ANIMAL; MALE; OLFACTORY BULB; PSYCHOTROPIC DRUGS; RATS;

EID: 0025303501     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/0163-7258(90)90043-2     Document Type: Review

References (108)

1. Structures posterior to the olfactory bulb which are responsible for the mouse killing and hyperactivity following lesions of the olfactory bulb
2. Mouse killing induced by PCPA injections or septal lesions, but not olfactory bulb lesions is similar to that of food deprived spontaneous killers
3. The dexamethasone suppression test: An overview of its current status in psychiatry
4. Etho experimental approaches to the biology of emotions
5. Serotonin-mimetic and antidepressant drugs on passive avoidance learning by olfactory bulbectomized rats
6. Corticosteron, cholineacetyl transferase and noradrenaline levels in olfactory bulbectomised rats in relation to changes in passive avoidance acquisition and open field activity
7. Major tranquilizers can be distinguished from minor tranquilizers on the basis of effects on marble burrying and swim induced grooming in mice
8. Postpartum depression and the effect of nomifensine treatment
9. The chronic effects of desipramine and sertraline on platelet and synaptosomal 5-HT uptake in olfactory bulbectomized rats
10. Olfactory bulbectomy: neural structures involved in irritability and aggression in the male rat
11. Olfactory bulbectomy as a model of depression
12. Facilitation of avoidance learning in anosmic rats by amitriptyline
13. The implication of noradrenaline in avoidance learning in the rat
14. Endogenous brain norepinephrine levels following bilateral olfactory bulb ablation
15. Effects of olfactory bulbectomy and domicile on stress induced corticosterone release in the rat
16. A new model for the detection of antidepressant drugs: olfactory bulbectomy compared with existing models
17. The effects of psychoactive drugs on plasmocorticosterone levels and behavior in the olfactory bulbectomised rat
18. Olfactory projection systems, drugs and behaviour: a review
19. The ability of 5.6.DHT injected into dorsal raphe projections to mimic surgical bulbectomy
20. Basal plasma corticosterone level after bilateral selective lesions of the olfactory pathways in the rat
21. Effects of lesions of the septal area and olfactory bulbs on sodium chloride intake
22. Peripheral serotonergic and adrenergic responses in depression
23. Evidence for inhibition by brain serotonin of mouse killing behaviour in rats
24. Olfactory lesions, emotionality and activity
25. Effects of two specific serotonin re-uptake inhibitors on the behaviour of the olfactory bulbectomised rat in the open field apparatus
26. Non-sensory involvement of the olfactory bulbs in the mediation of social behaviour
27. Olfactory system damage and brain catecholamines in the rat
28. The effect of amitriptyline and mianserin on food motivated behaviour of rats trained in a runway: possible correlation with biogenic amine concentrations in the limbic system
29. Olfactory regulation of maternal behaviour in rats: II. Effects of peripherally induced anosmia and lesions of the lateral olfactory tract in pup-induced killing
30. Effects of olfactory bulbectomy and peripherally induced anosmia on thermoregulation in the rat: susceptibility to antidepressant type drugs
31. Brain mechanisms of conditioned taste aversion learning: a review of the literature
32. Effects of bilateral olfactory bulbectomy in the rat alone or in the combination with antidepressants on the learned immobility model of depression
33. Stereospecificity of behavioural effects of viloxazine in bulbectomised rats does not correlate with its 5HT related action in vitro
34. Olfactory bulbectomy impairs the rat's radial maze behaviour
35. Monoamine related markers of depression changes following treatment
36. Peripheral adrenoceptors and serotonin receptors in depression: Changes associated with response to treatment with trazodone or amitriptyline
37. Minireview: The neurochemical sequella of olfactory bulbectomy
38. The amygdala and depression
39. Changes in brain catecholamine levels following olfactory bulbectomy and the effects of acute and chronic administration of desipramine in rats
40. Effects of some antidepressants and other psychotropic drugs on the behavior of olfactory bulbectomized rats in the open field
41. The effects of antidepressant drugs on conditioned taste aversion learning in the olfactory bulbectomised rat
42. The olfactory bulbectomized rat as a model of depression
43. Changes in neurotransmitter metabolism following olfactory bulbectmy in the rat
44. Animal models of depression: Parallels and correlates to severe depression in humans
45. 3H) imipramine ligand recognition sites in olfactory bulbectomise and sham-lesioned rats
46. Effects of antidepressant drugs on the behavior of olfactory bulbectomised and sham operated rats
47. The effects of Fluoxetine and Zimelidine on the behaviour of olfactory bulbectomised rats
48. Potentiation of pressor and behavioural responses to brain stimulation following bilateral olfactory bulbectomy in freely moving rats
49. Changes in blood pressure and heart rate following bilateral olfactory bulbectomy in rats
50. Effects of olfactory tract section on brain noradrenaline corticosterone and conditioning in the rat
51. Olfactory bulb projections to the parahippocampal area of the rat
52. Impaired mating performance in male rats induced peripherally or centrally
53. The olfactory control of meal pattern in rats
54. Neurochemical and neuropharmacological aspects of depression
55. Pharmacology of new antidepressants
56. Animal models of depression and the detection of anti-depressants
57. Some effects of the novel tricyclic antidepressant lofepramine on rodent models of depression
58. From animals to man: Advantages, problems and pitfalls of animal models in psychopharmacology
59. Anatomical, physiological and behavioral aspects of olfactory bulbectomy in the rat
60. Neurochemical and behavioural aspects of olfactory bulbectomy in the rat
61. The action of monoaminergic, cholinergic and gabaergic compounds in the olfactory bulbectomized rat model of depression
62. Fengabine a novel antidepressant gabaergic agent. 1. activity in models for antidepressant drugs and psychopharmacological profile
63. Enhancement of conditioned taste aversion by lesions of the midbrain raphé nuclei that deplete serotonin
64. Olfactory bulb removal decreases androgen receptor binding in amygdala and hypothalamus and disrupts masculine sexual behavior
65. Effects of bilateral lesions of the olfactory bulbs of rats on measures of learning and motivation
66. Human brain receptor alterations in suicide victims
67. Olfactory bulbectomy protects against pilocarpine induced motor limbic seizures in rats
68. Delayed emergence of anti-depressant efficacy following withdrawal in olfactory bulbectomised rats
69. The olfactory bulbectomized rat model of depression: a physiological behavioural and neurochemical investigation
70. Effect of stress on the secretion of corticosterone in the bulbectomized rat model of depression
71. Effect of chronic administration of the 6-aza analogue of mianserin (ORG 3770) and its enantiomers on behaviour and noradrenaline metabolism of olfactory bulbectomised rats in the ‘open field’ apparatus
72. The effect of chronically administered mianserin, 8-hydroxy mianserin and desmethyl mianserin on ‘open field’ behaviour and brain noradrenaline metabolism in the olfactory bulbectomized rats
73. Behavioural and neuropharmacological properties of the dibenzazepines, desipramine and lofepramine: studies on the olfactory bulbectomised rat model of depression
74. Antidepressant properties of the triazolobenzodiazepines alprazolam and adinazolam studies on the olfactory bulbectomised rat model of depression
75. Is there an abnormlity in neutrophil phagocytosis in depression?
76. Depressed neutrophil phagocytosis in the rat following olfactory bulbectomy reversed by chronic desipramine treatment
77. Effects of olfactory bulbablation on visual discrimination
78. Olfactory bulb removal: effects on brain norepinephrine
79. Behavioural despair in mice: a primary screening test for antidepressants
80. An experimental study of the projections of the amygdala to the accessory olfactory bulb and its relationship to the concept of a dual olfactory system
81. Effects of bulbectomisation, strain and gentling on emotionality and exploratory behaviour in rats
82. Effects of p-CPA on sleep in olfactory bulb lesioned rats
83. Sleep wakefulness rhythms in the olfactory bulb lesioned rat
84. Secondary brain changes following lesions a new paradigm for lesions a new paradigm for lesion experimentation
85. Synaptic organisation of the mammalian olfactory bulb
86. The effect of age on the development of hyperemotionality following bilateral olfactory bulbectomy in rats
87. The role of the olfactory system in avoidance learning and activity
88. Selective olfactory bulb lesions: reactivity changes and avoidance learning in rats
89. Changes in spontaneous, odor modulated and shock induced behavioral patterns following direct olfactory lesions
90. Review of the pharmacology of existing antidepressants
91. Gastrointestinal haemorhage, hyperglycaemia, azoteamia, hypercholesteraemia and hypernatraemia following lesions of the frontal lobe in man
92. Comparison of the effects of benzodiazepine and non-benzodiazepine anxiolytics on mouse killing behaviour in rats
93. Some behavioural effects of olfactory bulb damage in the rat
94. The effects of colony differences and olfactory bulb lesions on muricide in rats
95. Effects of olfactory bulb ablation upon emotionality and muricidal behavior in four rat strains
96. Olfactory bulb removal and response suppression in rats
97. Olfactory bulbectomy: emotional behaviour and defence responses in the rat
98. Decreased uptake of 5-hydroxytryptamine in blood platelets from patients with endogenous depression
99. Bulbectomy and sensitivity to estrogen: anatomical and functional specificity
100. Mouse killing behaviour (muricide) in the rat and the effect of antidepressants
101. Behavioural changes following olfactory bulbectomy in rats: a possible model for detection of antidepressant drugs
102. Kinaesthetic and organic sensations: their role in the reactions of the white rat to the maze
103. The validity of animal models of depression
104. Further behavioural and neurochemical studies on the olfactory bulbectomized rat
105. A new animal model for the prediction of antidepressant activity
106. Effects of locus coeruleus stimulation on muricide in olfactory bulbectomized and raphé lesione rats