Properties and functions of ATP-sensitive K-channels

Cellular Signalling

Volumn 2, Issue 3, 1990, Pages 197-214

  Ashcroft, Stephen J H ^a   Ashcroft, Frances M ^b  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

ATP sensitive K+ channel; Ion channel; sulphonylurea

Indexed keywords

ADENOSINE TRIPHOSPHATE; POTASSIUM CHANNEL; SULFONYLUREA;

HUMAN; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY;

ADENOSINE TRIPHOSPHATE; ANIMAL; ELECTRIC CONDUCTIVITY; GTP-BINDING PROTEINS; HUMAN; HYDROGEN-ION CONCENTRATION; POTASSIUM CHANNELS; RECEPTORS, DRUG; SIGNAL TRANSDUCTION; SULFONYLUREA COMPOUNDS; SUPPORT, NON-U.S. GOV'T;

EID: 0025300438     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/0898-6568(90)90048-F     Document Type: Short Survey

References (164)

1. Glucose dependent K+-channels in pancreatic?-cells are regulated by intracellular ATP
2. Glucose-induced excitation of hypothalamic neurones is mediated by ATP-sensitive K+ channels
3. Secretion and Its Control
4. The voltage-dependent block of ATP-sensitive potassium channels of frog skeletal muscle by caesium and barium ions.
5. Inhibition of ATP-regulated K+ channels precedes depolarization-induced increase in cytoplasmic free Ca2+ concentration in pancreatic beta-cells.
6. GTP and GDP activation of K+ channels that can be inhibited by ATP
7. Effects of sulfonamides on a metabolite-regulated ATPi-sensitive K+ channel in rat pancreatic B-cells.
8. Concentration-dependent effects of tolbutamide, meglitinide, glipizide, glibenclamide and diazoxide on ATP-regulated K+ currents in pancreatic B-cells
9. How do sulfonylureas approach their receptor in the B-cell plasma membrane?
10. Comparison of the effects of putative activators of K+ channels on pancreatic B-cell function
11. Molecular Mechanisms in Secretion
12. Effect of glibenclamide, a selective blocker of an ATP-K+ channel, on the anoxic response of hippocampal neurones
13. Changes in arterial K+ and ventilation during exercise in normal subjects and subjects with McArdle's syndrome.
14. Effects of activation of ATP-sensitive K+ channels in mammalian ventricular myocytes.
15. Kinetics of ATP-sensitive K+ channel revealed with oil-gate concentration jump method.