Prevention of diabetes in BB/Wor rats treated with monoclonal antibodies to interferon-γ

The Lancet

Volumn 336, Issue 8710, 1990, Pages 319-

  Nicoletti, Ferdinando ^a,b,c   Luigi Meroni, Pier ^a,b,c   Landolfo, Santo ^a,b,c   Gariglio, Marisa ^a,b,c   Guzzardi, Sandra ^a,b,c   Barcellini, Wilma ^a,b,c   Lunetta, Michele ^a,b,c   Mughini, Lanfranco ^a,b,c   Zanussi, Carlo ^a,b,c  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c UNIVERSITY OF CATANIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; DIABETES MELLITUS; LETTER; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMAL; ANTIBODIES, MONOCLONAL; DIABETES MELLITUS, INSULIN-DEPENDENT; INTERFERON TYPE II; RANDOM ALLOCATION; RATS; RATS, INBRED BB;

EID: 0025296156     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/0140-6736(90)91860-D     Document Type: Letter

References (6)

1. Aberrant expression of class II major histocompatibility complex molecules by B-cells and hyperexpression of class I major histocompatibility complex molecules by insulin containing islets in type-1 (insulin-dependent) diabetes mellitus
2. Retrovirus-induced changes in major histocompatibility complex antigen expression influence susceptibility to lysis by cytotoxic T lymphocytes
3. Pre-diabetes in the spontaneously diabetic BB/E rat: lymphocyte subpopulations and expression of rat MHC class II molecules in endocrine cells
4. Beta cell damage in diabetic insulinitis: are we approaching a solution?
5. Destruction of rat islet monolayers by cytokines: synergistic interactions of interferon gamma, tumour necrosis factor, lymphotoxin and interleukin 1
6. Interferon-gamma: pleiotropic effects on a rat pancreatic beta cell line