In vitro and in vivo Release of Soluble erbB‐2 Protein from Human Carcinoma Cells

Japanese Journal of Cancer Research

Volumn 81, Issue 5, 1990, Pages 489-494

  Mori, Shigeo ^a   Mori, Yasuyoshi ^b   Mukaiyama, Taketo ^c   Yamada, Yukinori ^a   Sonobe, Yoshiko ^b   Matsushita, Hirohisa ^b   Sakamoto, Goi ^d   Akiyama, Tetsu ^a   Ogawa, Makoto ^c   Shiraishi, Masato ^b   Toyoshima, Kumao ^a   Yamamoto, Tadashi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b Nichirei Co   (Japan)

^c Cancer Chemotherapy Center ^*

^d CANCER INSTITUTE   (Japan)

Author keywords

Breast; Carcinoma; Membrane protein; Oncogene; Receptor

Indexed keywords

MEMBRANE PROTEIN;

ARTICLE; BLOOD LEVEL; BREAST CARCINOMA; CELL CULTURE; FEMALE; GENE EXPRESSION; HISTOCHEMISTRY; HUMAN; HUMAN CELL; ONCOGENE C ERBB 2; PRIORITY JOURNAL; TISSUE LEVEL; TUMOR CELL;

ADENOCARCINOMA; BREAST NEOPLASMS; HUMAN; PROTO-ONCOGENE PROTEINS; RECEPTOR, ERBB-2; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL;

EID: 0025281021     PISSN: 09105050     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.1990.tb02596.x     Document Type: Article

References (19)

1. A v‐erbB‐related protooncogene, erbB‐2, is distinct from the c‐erbB‐1/epidermal growth factor‐receptor gene and is amplified in human salivary gland adenocarcinoma
2. The neu gene: an erbB‐homologous gene distinct from and unlinked to the gene encoding the EGF receptor
3. Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene
4. The product of human c‐erbB‐2 gene: a 185 kilodalton glycoprotein with tyrosine‐kinase activity
5. The neu oncogene encodes an epidermal growth factor receptor‐related protein
6. Amplification of c‐erbB‐2 oncogene in human adenocarcinomas in vivo
7. Localization of a novel v‐erbB related gene, c‐erbB‐2, on human chromosome 17 and its amplification in a gastric cancer cell line
8. Light and electron‐microscopical demonstration of c‐erbB‐2 gene product‐like immunoreactivity in human malignant tumors
9. Human breast cancer: correlation of relapse and survival with amplification of the HER‐2/neu oncogene
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12. Water‐soluble insulin receptor from human lymphocytes
13. Production of an epidermal growth factor receptor‐related protein
14. Soluble interleukin 2 receptors are released from activated human lymphoid cells in vitro
15. Overexpression of the EGF receptor‐related protooncogene erbB‐2 in human mammary tumor cell lines by different molecular mechanisms
16. A murine monoclonal antibody that recognizes an extracellular domain of the human c‐erbB‐2 protooncogene product
17. neu‐protein overexpression in breast cancer. Association with comedo‐type ductal carcinoma in situ and limited prognostic value in stage II breast cancer
18. C‐erbB‐2 gene product, a membrane protein commonly expressed on human fetal epithelial cells
19. Use of avidinbiotin‐peroxidase complex (ABC) in immunoperoxidase techniques